Chinese herbal medicine for subfertile women with polycystic ovarian syndrome - PubMed (original) (raw)

References to studies included in this review

Ainehchi 2019 {published data only}

1. 1. Ainehchi N, Khaki A, Farshbaf-Khalili A, Hammadeh M, Ouladsahebmadarek E. The effectiveness of herbal mixture supplements with and without clomiphene citrate in comparison to clomiphene citrate on serum antioxidants and glycemic biomarkers in women with polycystic ovary syndrome willing to be pregnant: a randomized clinical trial. Biomolecules 2019;9(6):215. - PMC - PubMed

Jin F 2016 {published data only}

1. 1. Jin F. Clinical study on the treatment of the decoction bushenhuoxue yang mo combined with clomifene on patients with kidney deficiency and blood stasis polycystic ovary syndrome infertility [Masters thesis]. Guangxi University of Chinese Medicine, 2016.

Li 2007 {published data only}

1. 1. Li XB, Li LY, Fu F, Hu XD. Clinical research on Lingzhu infusion and Shenqi capsule sequential therapy for polycystic ovarian syndrome. Zhong yi za zhi [Journal of Traditional Chinese Medicine] 2007;48(12):1079-81.

Liang 2008 {published data only}

1. 1. Liang RN, Liu J, Lu J. Treatment of refractory polycystic ovary syndrome by Bushen Huoxue method combined with ultrasound guided follicle aspiration. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2008;28(4):314-7. - PubMed

Liang YM 2017 {published data only}

1. 1. Liang YM. Therapeutic effect of Bushen Huoxue decoction on PCOS infertility patients with kidney deficiency and blood stasis syndrome[Masters thesis]. Hunan (China): Hunan University of Chinese Medicine, 2017.

Li Y 2012 {published data only}

1. 1. Li Y. Clinical observation of compound Xuanju capsule combined with clomiphene for polycystic ovary syndrome. Shanxi Journal of Traditional Chinese Medicine 2012;28(9):21-2.

Ma HX 2009 {published data only}

1. 1. Ma HX, Lai MH, Liu H, Song CX, Pan SY. Clinical observation of integrated therapy of Chinese and western medicine on 85 patients with infertility caused by PCOS. Hunan zhong yi yao da xue xue bao[Journal of Traditional Chinese Medicine University of Hunan] 2009;29(3):47-8, 78.

Ye 2007 {published data only}

1. 1. Ye DM, Xu LM, Lu RL. Clinical observation on laparoscopic ovarian electrocauterization combined with cycle treatment of traditional Chinese medicine for type phlegm-damp refractory polycystic ovary syndrome. Guangzhou zhong yi yao da xue xue bao[Journal of Guangzhou University of traditional Chinese medicine] 2007;24(6):445-8.

References to studies excluded from this review

An 2009 {published data only}

1. 1. An XQ, Liu GJ, Zhang JY, Cai FJ, An XT, Jiao SF. Curative efficacy of letrozole combined with traditional chinese medicine for ovulation dysfunction caused by polycystic ovarian syndrome. Zhong guo yao fang [China Pharmacy] 2009;20(29):2289-91.

An 2012 {published data only}

1. 1. An XQ. Clinical observation of compound XuanJu capsule combine with letrozole tablets treat 36 cases ovulation disorder in polycystic ovary syndrome. Hebei zhong yi [Hebei Journal of Traditional Chinese Medicine] 2012;34(7):1053-4.

Arentz 2014 {published data only}

1. 1. Arentz S, Abbott JA, Smith CA, Bensoussan A. Herbal medicine for the management of polycystic ovary syndrome (PCOS) and associated oligo/amenorrhoea and hyperandrogenism; a review of the laboratory evidence for effects with corroborative clinical findings. BMC Complementary and Alternative Medicine 2014;14:511. - PMC - PubMed

Arentz 2017a {published data only}

1. 1. Arentz S, Smith C A, Abbott J, Fahey P, Cheema BS, Bensoussan A. Combined Lifestyle and Herbal Medicine in Overweight Women with Polycystic Ovary Syndrome (PCOS): A Randomized Controlled Trial. Phytotherapy Research 2017;31(9):1330-40. - PMC - PubMed

Arentz 2017b {published data only}

1. 1. Arentz S, Smith C, Abbott JA, Fahey PP, Cheema BS, Bensoussan A. Randomized controlled trial of combined lifestyle and herbal medicine in women with polycystic ovary syndrome. Human Reproduction 2017;32(Supplement 1):i31-2. - PMC - PubMed

Bablis 2006 {published data only}

1. 1. Bablis P, Pollard H, Monti DA. Resolution of anovulation infertility using neuro emotional technique: a report of 3 cases. Journal Of Chiropractic Medicine 2006;5(1):13-21. - PMC - PubMed

Bai 2011 {published data only}

1. 1. Bai HY. Combine traditional Chinese and western medicine treatment of 94 cases of polycystic ovary syndrome. Qiu yi wen yao [Seek Medical And Ask The Medicine] 2011;9(6):169.

Bao 2009 {published data only}

1. 1. Bao WY. Treatment of polycystic ovary syndrome with nourishing kidney and resolving phlegm combined with blood activating. Tianjin zhong yi yao [Tianjin Journal of Traditional Chinese Medicine] 2009;26(5):375-6.

Bao 2014 {published data only}

1. 1. Bao Y, Bao Y, Piao CL, He Z. The clinical efficacy of polycystic ovarian syndrome insulin resistance and insulin resistance in non-treated control analysis. Maternal & Child Health Care of China 2014;29(30):4913-4.

Bei 2010 {published data only}

1. 1. Bei GZ. Clinical observation of jianpiqushi therapy joint healthy life style treating obesity polycystic ovarian syndrome [Masters thesis]. Guangzhou (China): Guang Zhou University of Chinese Medicine, 2010.

Cai 2006 {published data only}

1. 1. Cai LH. Clinical observation on shugan qingjie decoction in treating adolescent PCOS. Beijing Journal of Traditional Chinese Medicine 2006;25(6):323-6.

Cai 2011 {published data only}

1. 1. Cai XH. The kidney and liver soup treatment kidney empty stomach tone of childbearing age-to clinical observation of polycystic ovarian syndrome[Masters thesis]. Shandong (China): Shandong University of Traditional Chinese Medicine, 2011.

Cai 2012 {published data only}

1. 1. Cai XQ, Chen HJ, Liu Y. Combine traditional Chinese and western medicine treatment of infertility in 35 cases of clinical observation. Zhejiang Journal of Traditional Chinese Medicine 2012;47(6):411.

Cai 2014 {published data only}

1. 1. Cai W. Integrative Medicine 74 cases of polycystic ovary syndrome. World Health Digest 2014;4(15):115-6.

Cao 2010 {published data only}

1. 1. Cao WP. The Kidney and Liver Soup Treatment Kidney Empty Stomach Tone of Childbearing Age-to Clinical Observation of Polycystic Ovarian Syndrome[Masters thesis]. Shandong (China): Shandong Traditional Chinese Medicine University, 2010.

Cao 2012 {published data only}

1. 1. Cao ZY, Zhang XF. The kidney and treatment of kidney Yang deficiency and phlegm wet expectorant method the clinical research of infertility caused by polycystic ovary syndrome. Health Must-Read Magazine 2012;11(7):1.

Chan CC 2006 {published data only}

1. 1. Chan CC, Koo MW, Ng EH, Tang OS, Yeung WS, Ho PC. Effects of Chinese green tea on weight, and hormonal and biochemical profiles in obese patients with polycystic ovary syndrome-a randomized placebo controlled trial. Journal of the Society for Gynecologic Investigation 2006;13(1):63-8. - PubMed

Chan LY 2006 {published data only}

1. 1. Chan LY, Lau TK, Fung TM, Chow KM. Re: Effects of rosiglitazone on hormonal profile and ovulatory function in Chinese women with polycystic ovary syndrome. The Australian & New Zealand Journal Of Obstetrics & Gynaecology 2006;46(2):170-1. - PubMed

Chen 2005 {published data only}

1. 1. Chen LS, Zhou JT. Clinical research on combined therapy of Diane-35 with modified yougui pill on polycystic ovarian syndrome. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2005;25(9):794-6. - PubMed

Chen 2007 {published data only}

1. 1. Chen D, Chen SR, Shi XL, Guo FL, Zhu YK, Li S, et al. Clinical study on needle pricking therapy for treatment of polycystic ovarian syndrome. Zhongguo Zhen Jiu [Chinese Acupuncture & Moxibustion] 2007;27(2):99-102. - PubMed

Chen 2008 {published data only}

1. 1. Chen XP, Xie B, Zheng JP, Chen LF. Effect of nourishing kidney and dispersing stagnated hepatoqi decoction on symptoms and sex hormone of polycystic ovary syndrome patients with renal deficiency and hepatic stagnation. Chinese Journal of Information on Traditional Chinese Medicine 2008;15(5):17-9.

Chen 2009 {published data only}

1. 1. Chen J, Cui W, Li J, Sun W. Investigation on effect of electroacupuncture intervention on in vitro fertilization and embryo transfer of patients with polycystic ovarian syndrome. Maternal and Child Health Care of China 2009;24(30):4262-4.

Chen 2013 {published data only}

1. 1. Chen FL. 41 cases of anovulatory infertility clinical observation of combined Chinese and Western medicine to treat. Chinese and Foreign Medical Research 2013;11(6):38-9.

Chen 2015 {published data only}

1. 1. Chen XY. The efficacy of Huoxue Bushen decoction combined with western medicine treatment of polycystic ovary syndrome. Journal of Clinical Psychosomatic Diseases 2015;X21(1):24-5.

Chen 2016 {published data only}

1. 1. Chen J, Feng S, Zeng J, Wu X, Yang M, Tang H, et al. Effectiveness of electroacupuncture for polycystic ovary syndrome: study protocol for a randomized controlled trial. Trials 2016;17:256. - PMC - PubMed

Chen 2017 {published data only}

1. 1. Chen L, Tan Y, Chen SP. Effect of clomiphene citrate and Dingkun Dan on ovulation induction and clinical pregnancy of polycystic ovary syndrome. China Journal of Chinese Materia Medica 2017;42(20):4035-9. - PubMed

Cheng 2009 {published data only}

1. 1. Cheng MX, Li XL, Tong Q, Xu C. Therapeutic effect of traditional Chinese medicine on polycystic ovary syndrome. Journal of Difficult and Complicated Cases 2009;8(1):26-7.

Cheng 2014 {published data only}

1. 1. Cheng X, Guo J, Xie J. Association between levels of serum leptin and insulin resistance in patients with polycystic ovary syndrome. Zhonghua Liu Xing Bing Xue Za Zhi 2014;35(12):1389-91. - PubMed

Cheng 2015 {published data only}

1. 1. Cheng F, Zhang HL, Cheng L. Clinical research of Xiaonang Tiaojing decoction combined with chloramiphene in the treatment of polycystic ovarian syndrome. China Journal of Chinese Medicine 2015;30(7):1027-9.

Chen H 2010 {published data only}

1. 1. Chen H. Clinical observation of Yang Yin Qing Re Method for insulin resistance in polycystic ovary syndrome [Masters thesis]. SHnaghai (China): Shanghai University of Chinese Medicine, 2010.

Chen JL 2006 {published data only}

1. 1. Chen JL, Yang ZQ, Liu L. Clinical observation on 30 cases of hyperpimelic menostasia treated by Huatan tiaochong decoction. Hunan Journal of Traditional Chinese Medicine 2006;22(6):10-1.

Chen JX 2017 {published data only}

1. 1. Chen JX, Xu ZL, Dong BJ, Gu PL. Effect of Tiaojing Guchong decoction combined with Clomiphene on reproductive hormone, ovarian morphology and ovarian artery hemodynamics in infertile patients with polycystic ovary syndrome. Journal of Chinese Physician 2017;19(11):1707-9.

Chen L 2006 {published data only}

1. 1. Chen L. Comparison of efficacy of two ovulation inducing methods in treating PCOS with infertility. Modern Journal of Integrated Traditional Chinese and Western Medicine 2006;15(8):1035-6.

Chen LS 2012 {published data only}

1. 1. Chen LS, Chen J, Li SM. Combine traditional Chinese and western medicine treatment of refractory polycystic ovary syndrome infertility 31 cases of clinical analysis. Journal of Fujian University of Traditional Chinese Medicine 2012;22(6):10-3.

Chen N 2012 {published data only}

1. 1. Chen N. Huo Xue Li Shi decoction in the treatment of phlegm and blood stasis type of PCOS clinical observation [Masters thesis]. Shandong (China): Shandong University of Traditional Chinese Medicine, 2012.

Chen PL 2011 {published data only}

1. 1. Chen PL. Clinical Research on Treatment of Polycystic Ovary Syndrome (Type of Phlegm Stagnation) with Modified Erchen Decoction [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2011.

Chen QZ 2014 {published data only}

1. 1. Chen QZ. Due to polycystic ovary syndrome diagnosis and treatment of infertility. China Health Care & Nutrition 2014;(6):3863.

Chen R 2014 {published data only}

1. 1. Chen R, Wang C, Yan QY. Observation on therapeutic effect of polycystic ovary syndrome of damp-phlegm constitution treated with embedding therapy on back-shu points and front-mu points combined with needle-pricking therapy on Sifeng (EX-UE 10). Zhongguo Zhen Jiu [Chinese Acupuncture & Moxibustion] 2014;34(4):355-8. - PubMed

Chen RJ 2012 {published data only}

1. 1. Chen RJ. Clinical research about Xiao Nang Tiao Jing1Hao Fang on treatment of PCOS of stagnation of liver-qi type with the disease and to probe into Its mechanism of action [Masters thesis]. Hunan (China): Hunan University of Chinese Medicine, 2012.

Chen RR 2011 {published data only}

1. 1. Chen RR. TKRPM and resolving phlegm, dispelling stasis, combined with LE on treating the PCOS patients with ovulatory dysfunction [Masters thesis]. Nanjing (China): Nanjing University of Traditional Chinese Medicine, 2011.

Chen WY 2012 {published data only}

1. 1. Chen WY. Clinical observation on treating obese women with PCOS infertility in the integrative medicine. Clinical Journal of Chinese Medicine 2012;4(16):96-7.

Chen XF 2011 {published data only}

1. 1. Chen XF. Clinical research on laparoscopic surgery supplemented by Luo's ovulation soup for the treatment of kidney Yang deficiency type polycystic ovary syndrome [Masters thesis]. Fujian (China): Fujian University of Traditional Chinese Medicine, 2011.

Chen XF 2017 {published data only}

1. 1. Chen XF, Wei YH, Lv L, Liu JL. Study on the clinical effect of zuoguishugan decoction in the treatment of polycystic ovarian syndrome infertility. Chinese General Practice 2017;20(22):2796-800.

Chen XH 2010 {published data only}

1. 1. Chen XH, Huang BC, Kui Y. In: Abdominal needle combined with Chinese medicine treatment to insulin in patients with polycystic ovary syndrome.Guangdong institute of acupuncture and moxibustion academic conference;2010;Guangdong(China). Guangdong(China), 2010.

Chen Y 2014 {published data only}

1. 1. Chen Y. Clinical observation of Chinese medicine treatment of polycystic ovary syndrome. Medical Information 2014;6(20):477-8.

ChiCTR1800016219 {published data only}

1. 1. ChiCTR1800016219. Effects of Electroacupuncture and Chinese Herbs on the Female Germline Stem Cells in Granulosa Cells and clinical outcomes of PCOS Women with Kidney Deficiency Syndrome. Http://www.who.int/trialsearch/Trial2.aspx?TrialID=ChiCTR1800016219 (accessed 2 July 2019).

ChiCTR1800016792 {published data only}

1. 1. ChiCTR1800016792. Study on Metabolomic Mechanism of IVF Outcome of Traditional Chinese Medicine Patients with Shen Yang Deficiency PCOS: Prospective, Randomized, Controlled, Double-Blind Trial. apps.who.int/trialsearch/Trial2.aspx?TrialID=ChiCTR1800016792 (accessed 2 July 2019).

ChiCTR1800018597 {published data only}

1. 1. ChiCTR1800018597. Screening for Ovarian granulosa cell markers and experienced prescription of Chinese medicine (Jing Fang) in the treatment of PCOS. apps.who.int/trialsearch/Trial2.aspx?TrialID=ChiCTR1800018597 (accessed 2 July 2019).

ChiCTR‐IOR‐16008557 {published data only}

1. 1. ChiCTR-IOR-16008557. The Qilingwenshenxiaonang recipe in the treatment of patients with Polycystic ovary syndrome (PCOS): a multicenter, randomised, double-blind, placebo controlled trial. http://www.chictr.org.cn/showprojen.aspx?proj=14360 (accessed 9 June 2016). [ChiCTR-IOR-16008557]

ChiCTR‐IOR‐16008557 a {published data only}

1. 1. ChiCTR-IOR-16008557. The Qilingwenshenxiaonang recipe in the treatment of patients with Polycystic ovary syndrome(PCOS): a multicenter, randomised, double-blind, placebo controlled trial. http://apps.who.int/trialsearch/Trial2.aspx?TrialID=ChiCTR-IOR-16008557 (accessed 2 July 2019 ).

ChiCTR‐IPR‐16009166 {published data only}

1. 1. ChiCTR-IPR-16009166. Flavored filling in yiqi decoction phlegmy wet block type polycystic ovary syndrome prospective randomized controlled clinical study. http://www.chictr.org.cn/showprojen.aspx?proj=14956 (accessed 2 July 2019).

Chou 2018 {published data only}

1. 1. Chou L. The Cycle of Chinese Medicine Dialectical Therapy Combined with Clomifene Citrate in the Treatment ofPolycystic Ovary Syndrome and Effect of Comprehensive Safety Evaluation of Infertility. Pharmacy Today 2018;28(7):460-2.

Chu 2013 {published data only}

1. 1. Chu ES, Sze SC, Cheung HP, Liu Q, Ng TB, Tong Y. An in vitro and in vivo investigation of the antimetastatic effects of a Chinese medicinal decoction, Erxian Decoction, on human ovarian cancer models. Integrative Cancer Therapies 2013;12(4):336-46. - PubMed

Craig 2015 {published data only}

1. 1. Craig LB, Peck JD, Zhao D, Hansen KR. Clomid stair-step protocol may shorten the time to ovulation but not to pregnancy: A randomized clinical trial. Fertility and Sterility Conference: 71st Annual Meeting of the American Society for Reproductive Medicine, ASRM 2015 Baltimore, MD United States 2015;104(3):e97.

Cui 2012 {published data only}

1. 1. Cui XF, Mo XY. Kidney and eliminating phlegm method to treat high androgen levels, 50 cases of polycystic ovary syndrome. Jilin Journal of Traditional Chinese Medicine 2012;32(4):378-9.

Cui 2017 {published data only}

1. 1. Cui MH, Li T, Li XX. Analysis of the effect of acupuncture combined with medicine in the treatment of polycystic ovary syndrome with infertility. Journal of Practical Gynecologic Endocrinology 2017;4(32):35-6.

Dang 2012 {published data only}

1. 1. Dang HM, Liu YQ, Liu RX, Chen W. In: "Tiao jing zhu yun fang" combined with letrozole in women with polycystic ovary syndrome follicular development in patients with infertility and ovarian, uterine hemodynamic effects.Eighth National Integrative Medicine Obstetrics and Gynecology Academic Conference;2012. 2012.

Deng 2008 {published data only}

1. 1. Deng AL, Zhou ZM, Jiang HZ. Clinical research of integration of traditional Chinese medicine and western medicine in treating infertility caused by PCOS. Hubei Journal of Traditional Chinese Medicine 2008;30(12):18-9.

Deng 2016 {published data only}

1. 1. Deng CY, Wang Y, Zhang J. [Clinical treatment and effect observation of polycystic ovary syndrome infertility]. Health Guide 2016;(21):64.

Deng 2018 {published data only}

1. 1. Deng CY. The effect of Traditional Chinese Mdeicine plus acupuncture on polycystic ovarian syndrome with infertility. Clinical Journal of Chinese Medicine 2018;10(13):28-9.

Deveci 2015 {published data only}

1. 1. Deveci C, Demir B, Sengul O, Dilbaz B, Goktolga U. Clomiphene citrate 'stair-step' protocol vs. traditional protocol in patients with polycystic ovary syndrome: a randomized controlled trial. Archives of Gynecology & Obstetrics 2015;291(1):179-84. - PubMed

Ding 2015 {published data only}

1. 1. Ding CF, Chen WQ, Zhu YT, Bo YL, Hu HM, Zheng RH. Circulating microRNAs in patients with polycystic ovary syndrome. Human Fertility (Cambridge, England) 2015;18(1):22-9. - PubMed

Dong 2009 {published data only}

1. 1. Dong CY, Tian YM. Clinical observation on Traditional Chinese Medicine combined with Western medicine in treating PCOS. Inner Mongol Journal of Traditional Chinese Medicine 2009;24(7):84-5.

Dong 2010 {published data only}

1. 1. Dong CY, Tian YM. Clinical observation of "sheng ti gan qi fa" treat 30 cases of polycystic ovary syndrome. Hebei Journal of Traditional Chinese Medicine 2010;32(1):38-9.

Du 2012 {published data only}

1. 1. Du GH. Clinical study on the effect of kidney-nourishing and phlegm-resolving method combined with lifestyle adjustment treating obese women with polycystic ovary syndrome[Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2012.

Du 2013 {published data only}

1. 1. Du AZ. Integrative Medicine 28 cases of polycystic ovary syndrome. Chinese Medicine Morden Distance Education of China 2013;11(16):63-4.

Fan 2017 {published data only}

1. 1. Fan HY. Observation on the therapeutic effect of Bushen Zhuyun Decoction on polycystic ovarian syndrome infertility (kidney deficiency type)[Masters thesis]. Shanghai (China): Shanghai University of Traditional Chinese Medicine, 2017.

Fang 2004 {published data only}

1. 1. Fang RD, Li XR. Clinical observation on Chinese herbal medicine combined with western medicine in treating 50 cases of PCOS. Chinese Journal of Traditional Medical Science and Technology 2004;11(4):233-4.

Feng 2009a {published data only}

1. 1. Feng CF. Treating 50 cases of phlegm-damp type polycystic ovarian syndrome with combination of Chinese medicine and western medicine. Acta Chinese Medicine 2009;24(6):60-1.

Feng 2009b {published data only}

1. 1. Feng CF, Qin XJ, Xu JY. Clinical research on Chinese herbal medicine in treating 20 cases with PCOS. Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine 2009;9(2):42-4.

Feng J 2011 {published data only}

1. 1. Feng J, Zhang XF. Clinical observation of combine traditional Chinese and Western medicine treat polycystic ovary syndrome with infertility. Jilin Journal of Traditional Chinese Medicine 2011;31(9):858-60.

Feng X 2011 {published data only}

1. 1. Feng X. The clinical observation of Chinese and Western integrative medicine treating infertility caused by polycystic ovarian syndrome (PCOS) [Masters thesis]. Jilin (China): Jilin University, 2011.

Fu 2012 {published data only}

1. 1. Fu SW. Comprehensive treatment of polycystic ovary syndrome in Traditional Chinese Md. Xinli Yisheng 2012;(7):306-7.

Fu BJ 2019 {published data only}

1. 1. Fu BJ. Clinical Observation on Bailing Tiaogan Decoction in Infertility Due to Polycystic Ovary Syndrome. Guangming Journal of Chinese Medicine 2019;34(8):1202-4.

Fu JR 2019 {published data only}

1. 1. Fu JR. [Clinical observation on the treatment of infertility caused by polycystic ovary syndrome with the combination of traditional Chinese and Western Medicine]. China Health Vision 2019;(6):87.

Gao 2009 {published data only}

1. 1. Gao TY, Wang J, Wang J, Wang WH, Wang WJ, Lun ZJ. Effect of acupuncture assist IUI treatment on the outcome of infertility patients with polycystic ovarian syndrome. Reproduction and Contraception 2009;129(10):680-2.

Gao XL 2011 {published data only}

1. 1. Gao XL. Integrative medicine clinical observation of 90 cases of infertility polycystic ovary syndrome. Harebin Medical Journal 2011;31(2):123-4.

Gao YH 2011 {published data only}

1. 1. Gao YH. Clinical study on treatment of polycystic ovarian syndrome in type of splenic deficiency and phlegm-damp with Wu Ji powder[Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2011.

Ghavi 2015 {published data only}

1. 1. Ghavi F, Shakeri F. Effects of fennel on serum hormone levels in students with polycystic ovary syndrome. Avicenna Journal of Phytomedicine 2015;5:42-3.

Gong 2012 {published data only}

1. 1. Gong XH. Observation on effect of therapy of catgut implantation at acupoint on PCOS. Chinese Archives of Traditional Chinese Medicine 2012;30(9):2001-2.

Grant 2010 {published data only}

1. 1. Grant P. Spearmint herbal tea has significant anti-androgen effects in polycystic ovarian syndrome. A randomized controlled trial. Phytotherapy Research 2010;24(2):186-8. - PubMed

Gu 2015 {published data only}

1. 1. Gu LY, Wang Q, Du L, Zha QS, Gao H. [Metformin self side polycystic ovary syndrome phlegm clinical observation of 72 cases of amenorrhea]. Chinese Journal for Clinicians 2015;43(3):72-4.

Guo 2008 {published data only}

1. 1. Guo LC, Hu B. The study on traditional Chinese medicine in the treatment of 2cases of polycystic ovary syndrome complicated with 2-type diabetes mellitus. Hebei Journal of Traditional Chinese Medicine 2008;30(2):130-1.

Guo 2009 {published data only}

1. 1. Guo XY, Zhong HM, He HL, Liang HF. Clinical research of effect of wenshenhuatan capsule combined Diane-35 on polycystic ovarian syndrome. Modern Medicine & Health 2009;25(11):1606-7.

Guo AP 2011 {published data only}

1. 1. Guo AP. Integrative clinical observation on treatment of polycystic ovary syndrome. Journal of China Traditional Chinese Medicine Information 2011;3(17):395, 410.

Guo SX 2011 {published data only}

1. 1. Guo SX, Wang WJ, Gui SQ. Efficacy of Chinese patent medicine Tian Gui Capsule in patients with polycystic ovary syndrome:a randomized controlled trial. Journal of Chinese Integrative Medicine 2011;9(9):965-72. - PubMed

Haidari 2020 {published data only}

1. 1. Haidari F, Banaei-Jahromi N, Zakerkish M, Ahmadi K. The effects of flaxseed supplementation on metabolic status in women with polycystic ovary syndrome: A randomized open-labeled controlled clinical trial. Nutrition Journal 2020;19(1):8. - PMC - PubMed

Haj‐Husein 2016 {published data only}

1. 1. Haj-Husein I, Tukan S, Alkazaleh F. The effect of marjoram (Origanum majorana) tea on the hormonal profile of women with polycystic ovary syndrome: a randomised controlled pilot study. Journal Of Human Nutrition And Dietetics: The Official Journal Of The British Dietetic Association 2016;29(1):105-11. - PubMed

Han 2008 {published data only}

1. 1. Han YQ. Effective comparison of Traditional Chinese Medicine combined with western medicine ovulation inducing methods in treating PCOS with infertility]. China Practical Medicine 2008;3(9):49-50.

Han 2011 {published data only}

1. 1. Han L, Gong W. Clinical analysis of Guishen pill treat polycystic ovary syndrome. Chinese Journal of Experimental Traditional Medical Formulae 2011;17(24):216-7.

Han 2015 {published data only}

1. 1. Han ZY. Traditional Chinese Medicine therapy clinical observation period infertility polycystic ovary syndrome. Yiayao Qianyan 2015;5(34):317-8.

Han M 2013 {published data only}

1. 1. Han M. Clinical observation of integrative treatment of polycystic ovary syndrome. World Latest Medicine Information 2013;13(31):205-6.

Han SX 2013 {published data only}

1. 1. Han SX. Chinese medicine for reinforcing of kidney combined with diane- 35 for polycystic ovary syndrome. China Medicine and Pharmacy 2013;3(6):84-5.

Hao 2012 {published data only}

1. 1. Hao JJ. Clinical research on treating kidney deficiency and blood stasis type polycystic ovarian syndrome with Chinese medicine installments therapy and clomiphene citrate [masters thesis]. Shandong (China): Shandong Traditional Chinese Medicine University, 2012.

Harman 2001 {published data only}

1. 1. Harman J, Ward M. The role of nutritional therapy in the treatment of equine Cushing's syndrome and laminitis. Alternative Medicine Review: A Journal Of Clinical Therapeutic 2001;6 Suppl:S4-16. - PubMed

Hassanzadeh Bashtian 2013 {published data only}

1. 1. Hassanzadeh Bashtian M, Emami SA, Mousavifar N, Esmaily HA, Mahmoudi M, Mohammad Poor AH. Evaluation of fenugreek (Trigonella foenum-graceum L.), effects seeds extract on insulin resistance in women with polycystic ovarian syndrome. Iranian Journal of Pharmaceutical Research 2013;12(2):475-81. - PMC - PubMed

He 2009 {published data only}

1. 1. He HL, Xiao XF, Guo XY. Study of Wenshenhuatan capsule combined with Diane-35 on kidney asthenia an phlegmatic hygrosis type polycystic ovary syndrome. Modern Journal of Integrated Traditional Chinese and Western Medicine 2009;18(23):2749-50, 2753.

He 2010 {published data only}

1. 1. He P, Ding L. Clinical analysis of the treatment of anovulation patients with polycystic ovary syndrome by letrozole combined with traditional Chinese medicine. Yunnan Journal of Traditional Chinese Medicine and Materia Medical 2010;31(1):8-9.

He 2014 {published data only}

1. 1. He YY. Infertility clinical efficacy in combination therapy with polycystic ovary syndrome. Chinese Journal of Trauma and Disability Medicine 2014;66(17):102-3.

Heshmati 2020 {published data only}

1. 1. Heshmati J, Golab F, Morvaridzadeh M, Potter E, Akbari-Fakhrabadi M, Farsi F, et al. The effects of curcumin supplementation on oxidative stress, Sirtuin-1 and peroxisome proliferator activated receptor gamma coactivator 1alpha gene expression in polycystic ovarian syndrome (PCOS) patients: a randomized placebo-controlled clinical trial. Diabetes and metabolic syndrome: clinical research and reviews 2020;14:77-82. - PubMed

Hou 2000 {published data only}

1. 1. Hou JW, Yu J, Wei MJ. Study on treatment of hyperandrogenism and hyperinsulinism in polycystic ovary syndrome with Chinese herbal formula "tiangui fang". Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2000;20(8):589-92. - PubMed

Hu 2009a {published data only}

1. 1. Hu ZH, Wang Y, Shen HB. Study on impact of inserting Qihai and Sanyinjiao point on the endocrine changes in insulin resisting PCOS. Journal of Clinical Acupuncture & Moxibustion 2009;25(4):1-2.

Hu 2009b {published data only}

1. 1. Hu ZH, Wang Y. Study of the mechanism of acupuncture action on polycystic ovary syndrome of non-insulin resistance type. Shanghai Journal of Acupuncture and Moxibustion 2009;28(4):197-8.

Hu 2014 {published data only}

1. 1. Hu YY. Clinical observation of 35 cases of polycystic ovary syndrome Traditional Chinese Medicine Tiaozhou therapy combined therapy of metformin hydrochloride tablets. World Latest Medicine Information 2014;14(16):132-8.

Hua 2003 {published data only}

1. 1. Hua L, Wu YN, Zhang JM. Clinical study of Yishen jianpi yangxue tongli therapy in treating polycystic ovary syndrome. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2003;23(11):819-22. - PubMed

Huang 2004 {published data only}

1. 1. Huang YB, Gu ZT, Pan JY, Ruan CL, Lin QE. Clinical study on the treatment of clomiphene-resistant polycystic ovarian syndrome with laparoscopic ovarian drilling and drugs. Chinese Journal of Practical Gynecology and Obstetrics 2004;20(8):480-1.

Huang 2007 {published data only}

1. 1. Huang M, Lai H, Lv FB, Pan BQ. Massage, moxibustion combined with western medicine in treating PCOS. Chinese Manipulation and Qi Gong Therapy 2007;23(1):5-6.

Huang 2008 {published data only}

1. 1. Huang S, Chen AP. Traditional Chinese medicine and infertility. Journal of Community Medicine 2008;20(3):211-5. - PubMed

Huang 2010 {published data only}

1. 1. Huang XO. Clinical effect of treatment of Chinese medicine for sterility caused by polycystic ovarian syndrome. Clinical Medical Eengineering 2010;17(4):32-3.

Huang DL 2011 {published data only}

1. 1. Huang DL, Xu F, Wen YL, Xie NX. Acupuncture and Chinese medicine treatment of polycystic ovary syndrome-induced infertility in 30 cases. Journal of New Chinese Medicine 2011;43(8):86-6.

Huang L 2012 {published data only}

1. 1. Huang L. Traditional Chinese medicine of invigorating the kidney and resolving phlegm on the inhibin B level in patients with polycystic ovary syndrome [Masters thesisi]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2012.

Huang LH 2011 {published data only}

1. 1. Huang LH. Kidney and phlegm and dispelling stasis party clinical observation for the treatment of polycystic ovary syndrome with insulin resistance [Masters thesis]. Hubei (China): Hubei University of Chinese Medicine, 2011.

Huang LY 2006 {published data only}

1. 1. Huang LY, Xu CH. Yishen huoxue method in treating 50 cases of PCOS with infertility. Jilin Journal of Traditional Chinese Medicine 2006;26(12):19-20.

Huang XT 2012 {published data only}

1. 1. Huang XT, Luo GL. Clinical observation on combine traditional Chinese and western medicine treat polycystic ovary syndrome infertility. China Medical Engineering 2012;20(1):65-6.

Huang YL 2019 {published data only}

1. 1. Huang YL. Study on the effect of letrozole combined with sequential therapy of traditional Chinese medicine on infertility caused by polycystic ovary syndrome. Contemporary Medicine Forum 2019;17(10):215-6.

Huang YY 2006 {published data only}

1. 1. Huang YY, Yang XW, Deng MD. Clinical research of integration of traditional chinese medicine and western medicine in treating unmarried PCOS. New Journal of Traditional Chinese Medicine 2006;38(4):58-9.

Huang YZ 2019 {published data only}

1. 1. Huang YZ, Chen JL, Wu PW, Li Y. Bushen Yangmo Tang Combined with Clomiphene Has Effect on Reproductive Function of Patients with Polycystic Ovary Syndrome of Kidney Deficiency and Blood Stasis Type. Journal of New Chinese Medicine 2019;51(6):210-3.

Hung 2016 {published data only}

1. 1. Hung YC, Kao CW, Lin CC, Liao YN, Wu BY, Hung IL, et al. Chinese herbal products for female infertility in Taiwan: a population-based cohort study. Medicine 2016;95(11):e3075. - PMC - PubMed

Huo 2008 {published data only}

1. 1. Huo J, Yang SP, Xie BJ, Liao SG, Lin LP, Ding J, et al. Cytotoxic sesquiterpenoids from Vernonia bockiana. Journal of Asian Natural Products Research 2008;10(5-6):571-5. - PubMed

IRCT2017082016911N4 {published data only}

1. 1. IRCT2017082016911N4. Evaluation of the effect of capsule of date palm pollen in infertile women with polycystic ovary syndrome. http://apps.who.int/trialsearch/Trial2.aspx?TrialID=IRCT2017082016911N4 (accessed 2 July 2019).

Jalilian 2013 {published data only}

1. 1. Jalilian N, Modarresi M, Rezaie M, Ghaderi L, Bozorgmanesh M. Phytotherapeutic management of polycystic ovary syndrome: role of aerial parts of wood betony (Stachys lavandulifolia). Phytotherapy Research: PTR 2013;27(11):1708-13. - PubMed

Jamilian 2020 {published data only}

1. 1. Jamilian M, Foroozanfard F, Kavossian E, Aghadavod E, Shafabakhsh R, Hoseini A, et al. Effects of curcumin on body weight, glycemic control and serum lipids in women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. Clinical nutrition ESPEN. 2020;36:128-33. - PubMed

Jia, 2019 {published data only}

1. 1. Jia SL, Chen K, Wang LP, Zhao Y, Yang M. Xiaonang Pill Combined with Xiaonang Decoction in Treatment of Polycystic Ovary Syndrome. China Journal of Chinese Medicine 2019;34(4):839-42.

Jia 2004 {published data only}

1. 1. Jia YJ, Qv AP. Observation on the ultrasonogram of polycystic ovarian syndrome treated with traditional Chinese medicine, a report of 58 cases. Shanxi Journal of Traditional Chinese Medicine 2004;20(6):42-3.

Jia 2008 {published data only}

1. 1. Jia Y, Lu XH. Clinical research of integration of traditional Chinese medicine and western medicine in treating infertility caused by PCOS. Journal of Gansu College of Traditional Chinese Medicine 2008;25(3):37-8.

Jia 2010 {published data only}

1. 1. Jia Y, Jiang CL. "bushen huoxue qinggan fa" clinical studies with clomiphene citrate treatment of polycystic ovary syndrome. Journal of Hubei University of Chinese Medicine 2010;12(1):50-2.

Jia CM 2012 {published data only}

1. 1. Jia CM. Clinical observation on treating 60 cases of spleen deficiency type PCOS infertility in Traditional Chinese Medicine and moxibustion. Clinical Journal of Chinese Medicine 2012;4(16):47-8.

Jian 2011 {published data only}

1. 1. Jian QH. Clinical research on PCOS phlegmatic hygrosis syndrome treatment with kidney-invigoration and sputum-elimination method and liver-clearing and sputum-elimination method [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2011.

Jiang 2007 {published data only}

1. 1. Jiang WH, Xu XQ. Analysis of Yiulin decoction combined with laparoscope on sterility caused by PCOS. World Journal of Integrated Traditional and Western Medicine 2007;2(7):408-9.

Jiang 2014 {published data only}

1. 1. Jiang DS, Wu XQ, Zhang YC. [Effects of warm needling combined with zhangmo decoction on endometrial receptivity in patient with ovulation induction]. Zhongguo Zhen Jiu [Chinese Acupuncture & Moxibustion] 2014;34(2):130-4. - PubMed

Jiang 2015 {published data only}

1. 1. Jiang D, Zhang Y, Wu X, Wu S. Infertility in polycystic ovary syndrome treated with acupuncture and clomiphene: a randomized controlled trial. Zhongguo Zhen Jiu [Chinese Acupuncture & Moxibustion] 2015;35(2):114-8. - PubMed

Jiang JH 2011 {published data only}

1. 1. Jiang JH. Clinical study of nourishing kidney-·yin method on polycystic ovarian syndrome of deficiency of kidney-yin [Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2011.

Jiang MF 2011 {published data only}

1. 1. Jiang MF. Clinical research on polycystic ovarian syndrome's treatment with modified Cang Fu Dao Tan (CFDT) decoction [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2011.

Jia WH 2012 {published data only}

1. 1. Jia WH. Chinese medicine sub-cycle therapy-based treatment of 42 cases of polycystic ovary syndrome. China Practical Medical 2012;7(7):167-8.

Jin 2017 {published data only}

1. 1. Jin X， Liu HJ. Clinical observation on the treatment of infertility caused by polycystic ovary syndrome with the combination of traditional Chinese and Western Medicine. Modern Diagnosis & Treatment 2017;28(2):233-4.

Jin CL 2014 {published data only}

1. 1. Jin CL, Wei LX, Zhao JP, Wu ZC. Efficacy comparison between electroacupuncture and dyne-35 in treatment of polycystic ovary syndrome. Zhongguo Zhen Jiu [Chinese Acupuncture & Moxibustion] 2014;34(12):1174-8. - PubMed

Jing 2017 {published data only}

1. 1. Jing JB. Analysis of the clinical effect of Bushen Huatan Huoxue Method in the treatment of PCOS infertility. Henan Medical Research 2017;26(16):3025-6.

Jin JH 2016 {published data only}

1. 1. Jin JH. Efficacy of integrative medicine obese women with polycystic ovary syndrome. Maternal & Child Health Care of China 2016;31(1):187-8.

Jin XT 2014 {published data only}

1. 1. Jin XT, Ma K, Shan J. Clinical efficacy observation on therapy ovulation failure infertility caused by PCOS with reinforcing kidney, activating blood circulation and ovarian stimulation compound recipe. Zhongguo Zhong Yao Za Zhi [China Journal of Chinese Materia Medica] 2014;39(1):140-3. - PubMed

Johnson 2015 {published data only}

1. 1. Johnson LK, Holven KB, Nordstrand N, Mellembakken JR, Tanbo T, Hjelmesæth J. Fructose content of low calorie diets: effect on cardiometabolic risk factors in obese women with polycystic ovarian syndrome: a randomized controlled trial. Endocrine Connections 2015;4(3):144-54. - PMC - PubMed

Kang 2012 {published data only}

1. 1. Kang F, Kang Q, Zhang Q. Combine traditional Chinese and western medicine in the treatment of polycystic ovary syndrome research. Chinese Community Doctors 2012;14(32):169.

Kawakami 2011 {published data only}

1. 1. Kawakami Z, Ikarashi Y, Kase Y. Isoliquiritigenin is a novel NMDA receptor antagonist in kampo medicine yokukansan. Cellular and Molecular Neurobiology 2011;31(8):1203-12. - PubMed

Kitagawa 2015 {published data only}

1. 1. Kitagawa H, Munekage M, Ichikawa K, Fukudome I, Munekage E, Takezaki Y, et al. Pharmacokinetics of active components of Yokukansan, a traditional Japanese herbal medicine after a single oral administration to healthy Japanese volunteers: a cross-over, randomized study. PLoS One 2015;10(7):e0131165. - PMC - PubMed

Kort 2014 {published data only}

1. 1. Kort DH, Lobo RA. Preliminary evidence that cinnamon improves menstrual cyclicity in women with polycystic ovary syndrome: a randomized controlled trial. American Journal of Obstetrics and Gynecology 2014;211(5):487.e1-6. - PubMed

Kuang 2012 {published data only}

1. 1. Kuang LJ, He B. Efficacy analysis of treating PCOS by clomiphene plus Traditional Chinese Medicine artificial cycle. Clinical Journal of Chinese Medicine 2011;4(20):15-6.

Kuang 2013 {published data only}

1. 1. Kuang H, Li Y, Wu X, Hou L, Wu T, Liu J, et al. Acupuncture and clomiphene citrate for live birth in polycystic ovary syndrome: study design of a randomized controlled trial. Evidence-based Complementary and Alternative Medicine (eCAM) 2013;2013:527303. - PMC - PubMed

Kuang 2015 {published data only}

1. 1. Kuang H, Jin S, Hansen KR, Diamond MP, Coutifaris C, Casson P, et al. Identification and replication of prediction models for ovulation, pregnancy and live birth in infertile women with polycystic ovary syndrome. Human Reproduction 2015;30(9):2222-33. - PMC - PubMed

Kuek 2011 {published data only}

1. 1. Kuek S, Wang WJ, Gui SQ. Efficacy of Chinese patent medicine Tian Gui Capsule in patients with polycystic ovary syndrome: a randomized controlled trial. Zhong Xi Yi Jie He Xue Bao [Journal of Chinese Integrative Medicine] 2011;9(9):965-72. - PubMed

Lai 2006 {published data only}

1. 1. Lai YQ, Chen H, Duan LJ. Integration therapy of Chinese and western medicine in treating PCOS. Journal of Sichuan of Traditional Chinese Medicine 2006;24(3):74-5.

Lai 2011 {published data only}

1. 1. Lai MH, Ma HX, Liu H, Chen YL, Song XH, Ding T, et al. Chinese medicine fumigation for ovulation induction treatment of polycystic ovary syndrome patients with endometrial development. Chinese Journal of Traditional Medical Science and Technology 2011;8(4):335-6.

Lai 2014a {published data only}

1. 1. Lai L, Flower A, Moore M, Lewith G. Chinese herbal medicine and polycystic ovary syndrome: a randomized feasibility and pilot study in the United Kingdom. The Journal of Alternative and Complementary Medicine 2014;20(5):A61-2.

Lai 2014b {published data only}

1. 1. Lai L, Flower A, Moore M, Prescott P, Lewith G. Polycystic Ovary syndrome: a Randomised feasibility and pilot study using Chinese Herbal medicine to explore Impact on Dysfunction (ORCHID)—study protocol. European Journal of Integrative Medicine 2014;6(3):392-9.

Lai 2014c {published data only}

1. 1. Lai L, Li X, Flower A, Moore M, Liu J. Chinese herbal medicine for oligomenorrhoea and amenorrhoea in polycystic ovary syndrome: a systematic review and meta-analysis. Journal of Alternative & Complementary Medicine 2014;20(5):A129.

Lai 2015a {published data only}

1. 1. Lai L, Flower A, Moore M, Lewith G. Developing clinical practice guidelines for Chinese herbal treatment of polycystic ovary syndrome: A mixed-methods modified Delphi study. Complementary Therapies in Medicine 2015;23(3):430-8. - PubMed

Lai 2015b {published data only}

1. 1. Lai L, Flower A, Prescott P, Moore M, Lewith G. Chinese herbal medicine for oligomenorrhoea and amenorrhoea in polycystic ovary syndrome: A randomised feasibility study in the United Kingdom. European Journal of Integrative Medicine 2015;7(6):681-2. - PMC - PubMed

Lai 2015c {published data only}

1. 1. Lai L, Flower A, Prescott P, Moore M, Lewith G. Evaluating practitioner-blinding in Chinese herbal medicine research: Findings from a randomised feasibility study in the United Kingdom. Integrative Medicine Research 2015;4(1, Supplement):10.

Lai 2015d {published data only}

1. 1. Lai L, Flower A, Prescott P, Moore M, Lewith G. Treatment adherence in Chinese herbal medicine: Findings from a randomised feasibility study in the United Kingdom. Integrative Medicine Research 2015;4(1, Supplement):126.

Lai 2017 {published data only}

1. 1. Lai L, Flower A, Prescott P, Wing T, Moore M, Lewith G. Standardised versus individualised multiherb Chinese herbal medicine for oligomenorrhoea and amenorrhoea in polycystic ovary syndrome: a randomised feasibility and pilot study in the UK. BMJ open 2017;7(2):e011709. - PMC - PubMed

León‐Gonzalez 2014 {published data only}

1. 1. León-Gonzalez AJ, Acero N, Muñoz-Mingarro D, López-Lázaro M, Martín-Cordero C. Cytotoxic activity of hirsutanone, a diarylheptanoid isolated from Alnus glutinosa leaves. Phytomedicine: International Journal Of Phytotherapy And Phytopharmacology 2014;21(6):866-70. - PubMed

Li 2000 {published data only}

1. 1. Li XB, Li LY. Daotan Zhongzi formula combined with clomiphene in treating PCOS. Practical Medicine Journal 2000;16(4):330-1.

Li 2002 {published data only}

1. 1. Li XB, Li LY, Huang JL, Liang XF. Effect of operation under celioscopy combined with kidney tonifying and phlegm removing herbal medicine for polycystic ovarian disease syndrome. Traditional Chinese Drug Research & Clinical Pharmacology 2002;13(2):75-6, 131.

Li 2005 {published data only}

1. 1. Li XP. Chinese drugs of reinforcing kidney, clearing liver, and activating blood for treatment of infertility caused by polycystic ovary syndrome. Journal of Fujian College of Traditional Chinese Medicine 2005;15(4):9-11.

Li 2009 {published data only}

1. 1. Li L, Sun WF. Clinical research on kidney-tonifying and blood-activating therapy for the treatment of puberty polycystic ovarian syndrome. Journal of Guangzhou University of Traditional Chinese Medicine 2009;26(3):221-4.

Li 2011a {published data only}

1. 1. Li XP, Lin S, Ye S. Therapeutic efficacy of modified zigui decoction in treatment of polycystic ovary syndrome of gan-shen yin deficiency syndrome. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2011;31(8):1070. - PubMed

Li 2011b {published data only}

1. 1. Li XP, Ye S, Lin S, Zheng CS. Incites the last of the ten Heavenly Stems soup to add and subtract to the hepatorenal Yin deficient multi-pouch ovary syndrome high testosterone hormone blood' s sickness influence research. Guangming Journal of Chinese Medicine 2011;26(2):242-4.

Li 2015 {published data only}

1. 1. Li QG. Clinical study on compound norethindrone tablet combined with metformin in the treatment of polycystic ovary syndrome. Medical Recapitulate 2015;21(2):322-4.

Li 2018a {published data only}

1. 1. Li X, Zhou YY. Efficacy of Butu Yunzhong Decoction in Treatment of Ovulation Disorder Infertility of Polycystic Ovary Syndrome Phlegm and Dampness Syndrome. China Journal of Chinese Medicine 2018;33(5):840-3.

Li 2018b {published data only}

1. 1. Li X, Li QF, Zhou YY. Effects of Xiaonang Tiaojing Decoction on Ovarian Reserve and Follicular Development in Non-obese Polycystic Ovary Syndrome Patients. World Science and Technology-Modernization of Traditional Chinese Medicine 2018;20(5):710-5.

Li 2019a {published data only}

1. 1. Li YM, Huang NN, He SL. Effect of Yangyin Shugan Capsules and Clomiphene Citrate in the treatment of polycystic ovarian syndrome with infertility. China Medical Herald 2019;16(14):71-4.

Li 2019b {published data only}

1. 1. Li YM, Huang NN, He SL. Effect of Yangyin Shugan Capsules and Clomiphene Citrate in the treatment of polycystic ovarian syndrome with infertility. China Medical Herald 2019;16(14):71-4.

Lian 2008 {published data only}

1. 1. Lian F, Zhang YP, Liu YH, Ma FM, Sun ZG. In: Influence of Bushen Tiaochong on PCOS serum, TNF-a and IL-6 in follicle fluid, quality of oocyte.Colloquium of 8th National Traditional Chinese Medicine Gynecological Conference;2008. 2008.

Lian 2012 {published data only}

1. 1. Lian F, Zhao S. Effects of Shen invigorating and Chong-channel regulating method on anti-Müllerian hormone and oocyte quality in polycystic ovarian syndrome patients. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal Of Integrated Traditional And Western Medicine] 2012;32(1):9-12. - PubMed

Liang 2011 {published data only}

1. 1. Liang RW, Wang XY. Combine traditional Chinese and Western medicine treat infertility with Insulin resistance in follicular developmental delays. Medicial Innovation of China 2011;8(18):65-6.

Liang 2017 {published data only}

1. 1. Liang CR. Clinical Research of Traditional Chinese Medicine (TCM) Artificial Cycle Combined with Letrozole and Flexor Progesterone Therapy in Western Medicine on Treating PCOS Sterility. Journal of Liaoning University of Traditional Chinese Medicine 2017;19(3):206-8.

Liang 2019 {published data only}

1. 1. Liang R, Liu Z, Li P, Fan P, Xu L, Sun X, et al. Kuntai capsules improve glucolipid metabolism in patients with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled trial. Medicine 2019;98(39):Article Number: e16788. - PMC - PubMed

Liang HY 2018 {published data only}

1. 1. Liang HY, Nie RJ, Zhou XQ. The clinical effect of the combination of traditional Chinese and Western Medicine on infertility of polycystic ovary syndrome. Chinese Journal of Clinical Rational Drug Use 2018;11(3):92-3.

Liang XQ 2018 {published data only}

1. 1. Liang XQ. Therapeutic effect of Bushen Huoxue Decoction on PCOS infertility patients with kidney deficiency and blood stasis syndrome. Nei Mongol Journal of Traditional Chinese Medicine 2018;37(5):62-3.

Liao 2014 {published data only}

1. 1. Liao Q. Clinical study of combination therapy with polycystic ovary syndrome. Journal of Hei Longjiang Mendicine 2014;(12):1360-2.

Li B 2010 {published data only}

1. 1. Li B, Han JR. Clinical observation of combination of acupuncture with medicine treatment of polycystic ovary syndrome. Journal of Clinical Acupuncture and Moxibustion 2010;26(1):20-1.

Li C 2011 {published data only}

1. 1. Li C, Zhang SB. Acupuncture treatment clinical observation of 30 cases of polycystic ovary syndrome. Beijing Journal of Traditional Chinese Medicine 2011;30(2):128-9.

Li FY 2010 {published data only}

1. 1. Li FY, Wang Q. A warm nest soup treatment of 46 cases of kidney Yang deficiency type polycystic ovary syndrome curative effect. Journal of Shanxi College of Traditional Chinese Medicine 2010;11(4):10-1.

Li FY 2011 {published data only}

1. 1. Li FY. Combine traditional Chinese and Western medicine treatment of kidney Yang deficiency type PCOS clinical studies. Guiyang College of Traditional Chinese Medicine 2011.

Li HC 2011 {published data only}

1. 1. Li HC, Ma YJ, Wang XQ. Combined treatment of traditional Chinese medicine and Western medicine for insulin resistant polycystic ovarian syndrome associated infertility. Medical Journal of Qil 2011;26(1):31-2.

Li HX 2011 {published data only}

1. 1. Li HX, Ma WM, Gao XA, Liu Y. Chinese medicine PCOS patients in vitro fertilization - embryo transfer in assisted reproductive. Acta Chinese Medicine and Pharmacology 2011;39(6):77-8.

Li HX 2012 {published data only}

1. 1. Li HX, Ma WM, Gao XA, Liu Y. Influence of kidney-nourishing and phlegm-resolving drugs on endocrine of polycystic ovarian syndrome. Chinese Archives of Traditional Chinese Medicine 2012;30(3):554-5.

Li J 2012 {published data only}

1. 1. Li J. Combine traditional Chinese and Western medicine treatment of 62 cases of polycystic ovary syndrome combined insulin resistance. Guiding Journal of Traditional Chinese Medicine and Pharmacy 2012;18(7):60-1.

Li JY 2017 {published data only}

1. 1. Li JY, Tang Y, Yao L. Clinical Effect of Chinese Medicine,Moxibustion and Western Medicine in Treatment of Obese Patients with Infertility Caused by Polycystic Ovary Syndrome. World Chinese Medicine 2017;12(2):331-333,337.

Li K 2017 {published data only}

1. 1. Li K. The effect of moxibustion on umbilicus on ovulation and AMH in patients with PCOS ovulatory dysfunctional infertility [Masters thesis]. Shandong (China): Shandong University of Traditional Chinese Medicine, 2017.

Li L 2009 {published data only}

1. 1. Li XL, Wu XQ. [Clinical research on Chinese herbal medicine combined with western medicine in treating 40 cases of PCOS]. Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine 2009;9(2):40-2.

Lim 2011 {published data only}

1. 1. Lim CED, L JP. Traditional Chinese medicine for gynaecological diseases. Journal of the Australian Traditional-Medicine Society 2011;17(1):17-9.

Li M 2016 {published data only}

1. 1. Li M. A Randomized,Double—blind,Controlled,Multicenter ClinicalStudy on Bushen Culuan Recipe in treatment of ovulatorydysfunctional infertility. China Academy Chinese Medical Sciences 2016.

Lin 2005 {published data only}

1. 1. Lin Y. Combinative treatment of Chinese traditional and Western medicine in 48 patients with sterility due to polycystic ovarian syndrome. Maternal and Child Health Care of China 2005;20(13):1642-3.

Lin 2011 {published data only}

1. 1. Lin L, Chen J. Application of therapy of nourishing kidney essence in polycystic ovary syndrome patients with kidney deficiency after laparoscopic surgery. Journal of New Chinese Medicine 2011;43(9):63-5.

Li N 2013 {published data only}

1. 1. Li N. Efficacy and safety evaluation of acupuncture combined with auricular point sticking therapy in the treatment of polycystic ovary syndrome. Zhongguo Zhen Jiu [Chinese Acupuncture & Moxibustion] 2013;33(11):961-4. - PubMed

Lin 2017 {published data only}

1. 1. Lin S. The clinical effect of modified Wuling powder combined with acupuncture on multiple nests syndrome of kidney deficiency and phlegm stasis [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2017.

Lin 2017a {published data only}

1. 1. Lin LL. Chinese MedicineSelf-made Culuanpao Decoction in the Treatment of Polycystic Ovary Infertility 32 cases. Guangming Journal of Chinese Medicine 2017;32(18):2661-3.

Lin BQ 2013 {published data only}

1. 1. Lin BQ, Zhang ZM, Lin ZX, Liu Y, Zhong HZ, Yang Cx, et al. Transvaginal color Doppler monitoring the ovulation value of warm acupuncture combined with Erchen soup treatment in patients with polycystic ovary syndrome. International Medicine and Health Guidance News 2013;19(4):452-4.

Lin H 2013 {published data only}

1. 1. Lin H, Wang P, Huang Q, Zhong MY, Yang Y. [Effects of kidney-tonifying and collateral-activating prescription on sex hormone and ovary in patients with polycystic ovary syndrome]. Hunan Journal of Traditional Chinese Medicine 2013;29(10):11-2, 18.

Lin HM 2009 {published data only}

1. 1. Lin HM, Wu T. Clinical observation on Traditional Chinese Medicine combined with Western medicine in treating PCOS with infertility. Journal of Traditional Chinese Medicine University of Hunan 2009;29(7):55-7.

Lin HM 2013 {published data only}

1. 1. Lin HM, He HZ, Ma PL. Effect of insulin resistance in patients with polycystic ovary syndrome kidney phlegm on. Heilongjiang Journal of Traditional Chinese Medicine 2013;42(3):50-2.

Lin Y 2009 {published data only}

1. 1. Lin Y, Zhen SQ, Liang JL, Kong S. Clinical study on treatment of polycystic ovary syndrome with nuangongzhongzi recipe. Guangdong Medical Journal 2009;30(4):635-7.

Li Q 2016 {published data only}

1. 1. Li Q, Wang CY, Xu CH, Niu YH, Wang ZZ. [Clinical study of self yuan warm tone Yanxuesan treatment of polycystic ovary syndrome]. World Latest Medical Information Digest (continuous electronic journals) 2016;16(17):156-7.

Li SP 2011 {published data only}

1. 1. Li SP. Clinical and empirical study of reproductive hormones and glucose and lipid metabolism with WuJiSan in the treatment of polycystic ovary syndrome with type of stagnation of phlegm-damp [Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2011.

Li SZ 2010 {published data only}

1. 1. Li SZ. "bu shen tiao jing yu zi tang" combine with metformin treat 36 cases of infertility caused by polycystic ovary syndrome. Shanxi Journal of Traditional Chinese Medicine 2010;26(6):26-7.

Liu 2007 {published data only}

1. 1. Liu DM, Li SX. Observation on efficacy of Wuji baifeng pill combined with Diane-35 in treating 40 cases of PCOS with clomiphene resistance. Journal of New Chinese Medicine 2007;39(6):34-5.

Liu 2008 {published data only}

1. 1. Liu QC, Wu WH, Wu DY, Feng XW, Ma YH, Li JY, et al. Clinical observation on the treatment of childhood refractory idiopathic thrombocytopenic purpura with Dihuang Zhixue Capsule. Chinese Journal Of Integrative Medicine 2008;14(2):132-6. - PubMed

Liu 2009 {published data only}

1. 1. Liu X. [Observation on efficacy of herbs combined with clomiphene in treating PCOS]. China Pharmacy Medicine 2009;4(8):157-8.

Liu 2017 {published data only}

1. 1. Liu HM. Observation on the effect of the combination of Chinese and Western medicine in the treatment of infertility caused by polycystic ovary syndrome. Journal Of China Prescription Drug 2017;15(8):100-1.

Liu 2018 {published data only}

1. 1. Liu C, Ji N, Dang HM, Liu RX, Liu YQ. Clinical study on the treatment of polycystic ovary syndrome with kidney deficiency and liver depression by Tiaojing Zhuyun recipe. Chinese Journal of Integrated Traditional and Western Medicine 2018;38(3):316-20.

Liu B 2017 {published data only}

1. 1. Liu B. Clinical study on the treatment of infertility due topolycystic ovary syndrome of kidney deficiency and bloodstasis type by the combination of the periodic therapy oftraditional Chinese medicine with clomiphene citrate [Masters thesis]. Changchun (China): Changchun University of Chinese Medicine, 2017.

Liu CN 2017 {published data only}

1. 1. Liu CN, Liao XB, Zhou LY. Clinical Study on Traditional Chinese Medicine Four-stage Therapy Combined with Diane-35 in the Treatment of Polycystic Ovary Syndrome. Guangming Journal of Chinese Medicine 2017;32(9):1335-8.

Liu DP 2011 {published data only}

1. 1. Liu DP, Yan XJ. Integration of traditional Chinese and Western medicine in the treatment of 30 cases of infertility due to polycystic ovary syndrome. Modern Traditional Chinese Medicine 2011;31(4):14-6.

Liu GY 2010 {published data only}

1. 1. Liu GY, Tao LL, Xin J, Xie PP. The Impact of thread-embedding and Chinese medicine on hyperandrogenism of obese patients with polycystic ovary syndrome. Liaoning Journal of Traditional Chinese Medicine 2010;37(10):2027-8.

Liu HL 2011 {published data only}

1. 1. Liu HL. Integrative traditional and western medicine for 32 cases of polycystic ovary syndrome. Henan Traditional Chinese Medicine 2011;31(12):1420-1. - PubMed

Liu HX 2016 {published data only}

1. 1. Liu HX. Clinical Efficacy Observation of "Reinforcing the Kidney, Regulating the Liver and Stimulating Ovarian Compound" Recipe on Infertility Caused by PCOS. Shenzhen Journal of Integrated Traditional Chinese and Western Medicine 2016;26(12):38-40.

Liu JJ 2016 {published data only}

1. 1. Liu JJ. Observation on the therapeutic effect of Bushen Huoxue Shugan method on infertility caused by polycystic ovary syndrome. Modern Journal of Integrated Traditional Chinese and Western Medicine 2016;25(29):3282-3.

Liu Q 2014 {published data only}

1. 1. Liu Q. Influence the phlegm scattered plot PCOS patients with lipid metabolism and reproductive hormones. Journal of Chinese Medicinal Materials 2014;37(8):1502-4.

Liu RX 2010 {published data only}

1. 1. Liu RX, Shang HY, Liu YQ. In: "tiao jing zhu yun fang" combine with metformin for polycystic ovary syndrome.The Tenth National Gynecological Branch of China Association of Chinese Medicine Gynecology of Traditional Chinese Medicine Academic Conference. 2010:192-4, 202.

Liu XL 2014 {published data only}

1. 1. Liu XL. Clinical patients with polycystic ovary syndrome Integrative Medicine. Medical Information 2014;27(18):454.

Liu XX 2010 {published data only}

1. 1. Liu XX, Li XY, Liu YM, Meng ZM. Clinical observation of combine traditional Chinese and western medicine treat polycystic ovary syndrome with obesity. China Practical Medical 2010;5(34):129-30.

Liu XX 2012 {published data only}

1. 1. Liu XX. The clinical research on the treatment of invigorating the kidney and activating blood and resolving phlegm decoction to polycystic ovary syndrome and insulin resistance patients [Masters thesis]. Nanjing (China): Nanjing University Of Chinese Medicine, 2012.

Liu Y 2013 {published data only}

1. 1. Liu Y, Mao LH. Effect of danzhi xiaoyao pill on ovulation induction of polycystic ovarian syndrome patients of pathogenic fire derived from stagnation of gan-qi. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2013;33(9):1191-5. - PubMed

Liu YH 2010 {published data only}

1. 1. Liu YH, Li Y, Niu YH, Niu YL, Zhang WY. Study of kidney-reinforcing drugs combined with gonadotropin on infertile induced by polycystic ovary syndrome. Modern Journal of Integrated Traditional Chinese and Western Medicine 2010;19(1):13-4, 17.

Liu YP 2012 {published data only}

1. 1. Liu YP, Wang QH, Huang SH. Traditional Chinese Mdeicine and Western medicine treatment of the phlegm polycystic ovary syndrome Infertility 38 cases of clinical observation. Guide of China Medicine 2012;10(22):283-4.

Liu YQ 2012 {published data only}

1. 1. Liu YQ. LiuRunXia treatment of polycystic ovary syndrome, a professor at the academic thoughts and clinical experience in the research of infertility. China Academy of Chinese Medical Sciences 2012.

Li XB 2011 {published data only}

1. 1. Li XB, Zhai JL, Li LY, HU XD. Influence of Lingzhu granules on endocrine and lipid metabolism of polycystic ovary syndrome patients. Journal of Traditional Chinese Medicine 2011;52(1):31-4.

Li XH 2011 {published data only}

1. 1. Li XH. Clinical observation of Integrative Medicine treat 30 cases of polycystic ovary syndrome. Yunnan Journal of Traditional Chinese medicine and Material Medical 2011;32(1):12-4.

Li XL 2009 {published data only}

1. 1. Li L, Sun WF. Clinical research on Traditional Chinese Medicine Bushen huoxue method in treating endocrinological metabolism of adolescent PCOS. Practical Medicine Journal 2009;25(13):2177-9.

Li XP 2011 {published data only}

1. 1. Li XP, Lin S, Ye S, Cai YS, Chen CM, Zheng CS. Therapeutic efficacy of modified zigui decoction in treatment of polycystic ovary syndrome of gan-shen yin deficiency syndrome. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2011;31(8):1070-3. - PubMed

Li XW 2009 {published data only}

1. 1. Li XW, Geng JF. Clinical observation on Chinese herbal medicine combined with Western medicine in treating 95 cases of PCOS. Chinese Journal of Modern Drug Application 2009;3(7):122-3.

Li XY 2017 {published data only}

1. 1. Li XY, Yang Q, Wang Q. Effects of Cangfu Daotan Decoction Combined with Clomiphene on Serum Hormone Level and Endometri-al Receptivity in Patients with Polycystic Ovary Syndrome Combined with Infertility. China Pharmacy 2017;28(26):3698-701.

Li Y 2013 {published data only}

1. 1. Li Y, Ma H, Zhang Y, Kuang H, Ng EH, Hou L, et al. Effect of berberine on insulin resistance in women with polycystic ovary syndrome: study protocol for a randomized multicenter controlled trial. Trials 2013;14:226. - PMC - PubMed

Li YL 2011 {published data only}

1. 1. Li YL, Lian F, Wang RX, Zhang N. Observation of Clomiphene citrate resistant polycystic ovary syndrome treated by combination of acupuncture, Chinese and Western medicine. Hebei Journal of Traditional Chinese Medicine 2011;32(7):244-6.

Li ZZ 2010 {published data only}

1. 1. Li ZZ. The clinical study of using Cang Fu Dao Tan Wan in the treatment of PCOS of the phlegm stagnation syndrome[Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2010.

Lu 2010 {published data only}

1. 1. Lu J, Chen YX, Li FY, Chen Y. Clomiphene joint mountain continued Fu Rong Dao Tan Tang treatment of polycystic ovary syndrome analysis of 48 cases. Maternal and Child Health Care of China 2010;25(1):138-9.

Lu 2012 {published data only}

1. 1. Lu LF. Chinese cycle therapy combined with clomiphene citrate treatment of polycystic ovary syndrome infertility efficacy analysis. Health Must Read Magazine 2012;11(9):91.

Lu 2018 {published data only}

1. 1. Lu T. Effect of Shugan Qutan Sanyu decoction Combined with acupuncture on infertility in patients with polycystic ovary syndrome. Medical Journal of Chinese People's Health 2018;30(23):67-9.

Luo, 2019 {published data only}

1. 1. Luo J, Li ZY, Li Y. Observation on the curative effect of Yangjingzhongyu Decoction combined with moxibustion in the treatment of infertility caused by ovulation disorders in polycystic ovary syndrome. Journal of Sichuan Traditional Chinese Medicine 2019;37(5):147-50.

Luo 2010 {published data only}

1. 1. Luo J, Guo R. Clinical observation on invigorating kidney to remove phlegm and stasis in treating PCOS-IR. Hubei Journal of Traditional Chinese Medicine 2010;32(6):24-5.

Luo 2014 {published data only}

1. 1. Luo L, Chen J. Polycystic ovary syndrome clinical observation type of treatment. Chinese and Foreign Medical Research 2014;12(29):5-7.

Luo 2018 {published data only}

1. 1. Luo R, Yan PX, Zhu XT, Zheng WJ, Zhang L, Sheng JW et al. Effect of acupuncture and medicine on infertility due to polycystic ovary syndrome with kidney deficiency. China Medical Herald 2018;15(30):149-52.

Luo 2019 {published data only}

1. 1. Luo JQ. The effect of Jiangzhi ovulation formula combined with ethinylestradiol and cyproterone on the level of lipid metabolism related factors in patients with polycystic ovary syndrome. Maternal & Child Health Care of China 2019;34(5):1012-5.

Lv 2007 {published data only}

1. 1. Lv XP, Cong HF, Wang XB. Observation on efficacy of acupuncture combined with medication in treating ovulation failure induced by PCOS. Journal of Clinical Acupuncture and Moxibustion 2007;23(8):35-6.

Lv 2009 {published data only}

1. 1. Lv LP, Chen GS. Jiawei buzhong yiqi decoction combined with diane-35 in treating 30 cases of PCOS. Jiangxi Journal of Traditional Chinese Medicine 2009;40(5):42-3.

Lv 2010 {published data only}

1. 1. Lv JW. Clinical study on polycystic ovary syndrome patient’s hyperplasia of mammary gland treated by method of tonifying-kidney and regulating-menstruation [Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2010.

Ma 2009 {published data only}

1. 1. Ma HX, You ZL, Lai MH. Clinical observation of integration of traditional Chinese medicine and Western medicine in treating infertility caused by obese PCOS. Guiding Journal of Traditional Chinese Medicine and Pharmacy 2009;15(7):19-20.

Ma 2010 {published data only}

1. 1. Ma MH, Wang XD. The application of method regulating kidney & clearing lung in the treatment of 26 cases with hyperandrogenism caused by PCOS. Journal of Nanjing University of Traditonal Chinese Medicine 2010;26(4):311-2.

Ma 2017 {published data only}

1. 1. Ma LH. Clinical observation on the treatment of polycystic ovary syndrome in the treatment of polycystic ovary syndrome. Journal of Practical Gynecologic Endocrinology 2017;4(10):64-5.

Ma 2018 {published data only}

1. 1. Ma R, Wang XM, Zhu XL. Clinical Efficacy of Bushen Tiaochong Decoction in Obesity Patients with Polycystic Ovary Syndrome and Effect on Endometrial Receptivity. Chinese Journal of Experimental Traditional Medical Formulae 2018;24(5):188-92.

Madder 2013 {published data only}

1. 1. Madder LS. Treating PCOS naturally. HerbalGram (HERBALGRAM) 2013;Jun-May(98):58-65.

Mao 2003 {published data only}

1. 1. Mao YX. Clinical observation of 3 kinds different ovulation stimulating methods on polycystic ovary syndrome. Heilongjiang Medical Journal 2003;27(7):489-90.

Mao XG 2011 {published data only}

1. 1. Mao XG, Fang SS, Mao AH. Observation research of 80 cases of polycystic ovary syndrome using combination of Chinese traditional and Western medicine. Chinese Journal of Ethnomedicine and Ethnopharmacy 2011;20(24):36-7.

Mao XH 2011 {published data only}

1. 1. Mao XH. Clinical observation of traditional Chinese combine with western medicine treatment of polycystic ovarian syndrome. Shanxi Journal of Traditional Chinese Medicine 2011;27(7):27-8.

Mei 2010 {published data only}

1. 1. Mei JL. Clinical study on the effect of kidney-nourishing and phlegm-resolving method combined with Diane-35 treating kidney-deficiency and phlegm-dampness type of polycystic ovary syndrome accompanied hyperandrogenism [Masters thesis]. Nanjing (China): Nanjing University of Traditional Chinese Medicine, 2010.

Men 2017 {published data only}

1. 1. Men A. Clinical Observation of Treating Patients with RenalDeficiency and Blood Stasis-type PCOS Infertility withBushen Huoxue Zhongzi Recipe [Masters thesis]. Henan (China): Henan University of Chinese Medicine, 2017.

Meng 2011 {published data only}

1. 1. Meng J. Clinical and empirical study on therapeutic effects of Ling-Zhu granule in polycystic ovary syndrome and insulin resistance [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2011.

Miao 2012 {published data only}

1. 1. Miao Y. Clinical analysis of combine traditional Chinese and western medicine treatment of polycystic ovarian syndrome. Guangming Journal of Chinese Medicine 2012;27(8):1619-20.

Ming‐Wei 2011 {published data only}

1. 1. Ming-wei X, Xin-yun L, Jun-qin H. Regulation and control of wenshen yangxue granule combined with clomifene citrate on INH-ACT-FS system in patients with follicular maldevelopment infertility. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2011;31(12):1596-600. - PubMed

Mohammad Hosseinzadeh 2016 {published data only}

1. 1. Mohammad Hosseinzadeh F, Hosseinzadeh-Attar MJ, Yekaninejad MS, Rashidi B. Effects of selenium supplementation on glucose homeostasis and free androgen index in women with polycystic ovary syndrome: A randomized, double blinded, placebo controlled clinical trial. Journal of Trace Elements in Medicine and Biology: organ of the Society for Minerals and Trace Elements (GMS) 2016;34:56-61. - PubMed

Moradan 2012 {published data only}

1. 1. Moradan S. Is there any role for acupuncture in infertility treatment? International Journal of Fertility & Sterility 2012;6:114.

Mosalanejad 2015 {published data only}

1. 1. Mosalanejad L, Shakeri F, Ghavi F. The effect of asafoetida on hormone levels of students with polycystic ovary syndrome. Avicenna Journal of Phytomedicine 2015;5:106-7.

Motoo 2014 {published data only}

1. 1. Motoo Y, Arai I, Tsutani K. Use of Kampo diagnosis in randomized controlled trials of Kampo products in Japan: a systematic review. PLoS One 2014;9(8):e104422. - PMC - PubMed

Musumeci 2006 {published data only}

1. 1. Musumeci ML, Schlecht K, West DP, West LE, Innocenzi D, Micali G. The spectrum of systemic therapy and procedural approaches in the management of moderate to severe acne vulgaris: A review. Giornale Italiano di Dermatologia e Venereologia 2006;141(4):379-91.

Naeimi 2020 {published data only}

1. 1. Naeimi S A, Tansaz M, Hajimehdipoor H, Saber S. Comparing the effect of Nigella sativa oil soft gel and placebo on oligomenorrhea, amenorrhea and laboratory characteristics in patients with polycystic ovarian syndrome, a randomized clinical trial. Research journal of pharmacognosy 2020;7(1):49-58.

NCT01116167 {published data only}

1. 1. Li Y, Kuang H, Shen W, Ma H, Zhang Y, Stener-Victorin E, et al. Letrozole, berberine, or their combination for anovulatory infertility in women with polycystic ovary syndrome: study design of a double-blind randomised controlled trial. BMJ Open 2013;3(11):e003934. - PMC - PubMed

NCT03264638 {published data only}

1. 1. Sun AJ. A Clinical and Biological Research of Combined Chinese and Western Medicine in the Treatment of PCOS. Https://clinicaltrials.gov/show/nct03264638 (accessed 2 July 2019) 2017;NCT03264638.

Nie 2018 {published data only}

1. 1. Nie L, Wang HX, Huang SL, Xiong J. Analysis on the therapeutic effect of Tonifying the kidney, promoting blood circulation and removing phlegm regulating Chinese medicine combined with western medicine on PCOS infertility (Intrinsic Phlegm Dampness Syndrome). China Modern Doctor 2018;56(12):59-62,65.

O'Brien 2010 {published data only}

1. 1. O'Brien PE. Bariatric surgery: mechanisms, indications and outcomes. Journal of Gastroenterology and Hepatology 2010;25(8):1358-65. - PubMed

Pan 2010 {published data only}

1. 1. Pan H. The investigation simplify the assayed of the insulin resistance of polycystic ovary syndrome and interfering in clinical treatment of Chinese medicinal materials [Masters thesis]. Nanjing (China): Nanjing University Of Chinese Medicine, 2010.

Pan 2012 {published data only}

1. 1. Pan LZ, Wang Y, He S. Clinical efficacy on 101 cases of intractable infertility of polycystic ovary syndrome treated with integrative Chinese and Western medicine. World Journal of Integrated Traditional and Western Medicine 2012;7(1):40-2, 65.

Pastore 2011 {published data only}

1. 1. Pastore LM, Williams CD, Jenkins J, Patrie JT. True and sham acupuncture produced similar frequency of ovulation and improved LH to FSH ratios in women with polycystic ovary syndrome. The Journal Of Clinical Endocrinology And Metabolism 2011;96(10):3143-50. - PMC - PubMed

Pazyar 2012 {published data only}

1. 1. Pazyar N, Yaghoobi R. A rationale of ginseng as a novel addition to the antihirsutism armamentarium. Journal Of Alternative And Complementary Medicine (New York, NY) 2012;18(3):210-1. - PubMed

Pei 2012 {published data only}

1. 1. Pei YX, Li JC, Ma YB, Hu LH. [Clinical observation of traditional Chinese and western medicine for polycystic ovary syndrome]. Hebei Journal of Traditional Chinese Medicine 2012;34(5):703-4.

Peng 2012 {published data only}

1. 1. Peng YT. Clinical observation on Gui-zhi-fu-ling-wan with catgut embedding therapy to treat blood stagnation type of PCOS [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2012.

Qiao 2012 {published data only}

1. 1. Qiao SX. The clinical research on Chinese medicine sequential with the acupuncture treat anovulation infertility caused by PCOS [Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2012.

Qin 2016 {published data only}

1. 1. Qin W, Zhao K, Yang H. Effect of acupoint catgut embedding therapy combined with Chinese medicine for nourishing the kidneys and promoting blood circulation and improving blood glucose and lipid levels as well as the pregnancy rate in obese PCOS patients with infertility. Experimental & Therapeutic Medicine 2016;12(5):2909-14. - PMC - PubMed

Qiu 2006 {published data only}

1. 1. Qiu HN, Xu J. Clinical observation on acupuncture in treating 46 cases of obese PCOS patients. Chinese Community Doctors 2006;8(14):86-7.

Qu 2015 {published data only}

1. 1. Qu J, Che Y, Xu P, Xia Y, Wu X, Wang Y. The higher response of vascular endothelial growth factor and angiotensin-II to human chorionic gonadotropin in women with polycystic ovary syndrome. International Journal of Fertility & Sterility 2015;8(4):373-8. - PMC - PubMed

Qv 2011 {published data only}

1. 1. Qv HY, Li MZ, Chen HS. Clinical observation of combining traditional Chinese and Western medicine treatment of polycystic ovarian syndrome. Chinese Journal of Aesthetic Medicine 2011;20(6):390.

Ran 2008 {published data only}

1. 1. Ran MX, Song ZH, Zhang H, Tai GX, Chen Q. An clinical observation and experimental research on the ovulation induction therapy of western medicines combined with Chinese herbs for the anovulatory patients with PCOS. Guangming Journal of Chinese Medicine 2008;23(2):175-6.

Ran MX 2007 {published data only}

1. 1. Ran MX, Zhang H, Qi XJ, Nie XX, Chen Q. An experimental research on endometrial receptivity is affected by bushenhuoxue Chinese herbs. Chinese Journal of Birth Health and Heredity 2007;15(4):56-7, 78.

Ran XM 2007 {published data only}

1. 1. Ran XM, Zhang H, Tai GX, Song ZH, Chen Q. The influence of Yulin formula on CTmRNA expression of endometrium after ovulation inducing. Traditional Chinese Medicinal Research 2007;20(2):29-31.

Rao 2012 {published data only}

1. 1. Rao XH, Zhang Y. A clinical analysis of treating the anovulation type of infertility in the integrative medicine. Clinical Journal of Chinese Medicine 2012;4(22):71-2.

Rashidi 2013 {published data only}

1. 1. Rashidi BH, Tehrani ES, Hamedani NA, Pirzadeh L. Effects of acupuncture on the outcome of in vitro fertilisation and intracytoplasmic sperm injection in women with polycystic ovarian syndrome. Acupuncture in Medicine: Journal of the British Medical Acupuncture Society 2013;31(2):151-6. - PubMed

Ren, 2019 {published data only}

1. 1. Ren XX, Wan YR, Xiao HDZ, Wei AW. Shen Tiaojing Yuzi Decoction Combined with Letrozole Tablets in the Treatment of 46 Cases of Polycystic Ovary Syndrome Infertility. Traditional Chinese Medicinal Research 2019;32(5):14-6.

Ren 2002a {published data only}

1. 1. Ren XQ. Comparison of effect of two ovulation inducing methods in treating refractory PCOS with infertility. Guangxi Medical Journal 2002;24(8):1165-7.

Ren 2002b {published data only}

1. 1. Ren XQ. Comparison of effect of two ovulation inducing methods in treating refractory PCOS with infertility. Journal of Practical Obstetrics and Gynecology 2002;18(6):351-2.

Ren 2006 {published data only}

1. 1. Ren QL, Tan Y. Influence of Ziyin buyang method on serum IGF-1 and sexual hormone in PCOS patients. Jiangsu Journal of Traditional Chinese 2006;27(5):28-9.

Ren 2008 {published data only}

1. 1. Ren QL, Tan Y, Sun LZ. Clinical research of Chinese Ziyin buyang formula sequentially treating 31 cases with PCOS. Jiangsu Journal of Traditional Chinese 2008;40(3):40-2.

Ren 2011 {published data only}

1. 1. Ren WK. Exploration of follicle stimulating prescription and luteotrophic prescription in the co-treatment of polycystic ovarian syndrome with kidney deficiency and blood stasis [Masters thesis]. Shandong (China): Shandong University of Traditional Chinese Medicine, 2011.

Ren 2013 {published data only}

1. 1. Ren MY, Zhu MC. Integrative medicine 150 cases of infertility salpingitic. Guangming Journal of Chinese Medicine 2013;28(11):2266-7.

Ren 2014 {published data only}

1. 1. Ren LN, Guo LH, Ma WZ, Zhang R. A meta-analysis on acupuncture treatment of polycystic ovary syndrome. Zhen Ci Yan Jiu [Acupuncture Research] 2014;39(3):238-46. - PubMed

Ren 2019 {published data only}

1. 1. Ren XX, Wan YR, Xiao HDZ, Wei AW. [46 cases of polycystic ovary syndrome infertility treated with Bushen Tiaojing Yuzi Decoction and letrozole tablets]. Traditional Chinese Medicinal Research 2019;32(5):14-6.

Ried 2015 {published data only}

1. 1. Ried K. Chinese herbal medicine for female infertility: an updated meta-analysis. Complementary Therapies in Medicine 2015;23(1):116-28. - PubMed

Ruan 2016 {published data only}

1. 1. Ruan HB, Wang MZ, Wu TT, Liu X, Mo WW. Clinical Effect of Bushen Quyu Recipe Combined with Acupuncture in Treatment of Clomiphene-resistant Polycystic Ovary Syndrome Infertility Patients after Cold Needle Puncture Drainage Operation. Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi= Chinese journal of integrated traditional and Western medicine 2016;36(9):1038-41. - PubMed

Sadrefozalayi 2014 {published data only}

1. 1. Sadrefozalayi S, Farokhi F. Effect of the aqueous extract of Foeniculum vulgare (fennel) on the kidney in experimental PCOS female rats. Avicenna Journal of Phytomedicine 2014;4(2):110-7. - PMC - PubMed

Salah 2013 {published data only}

1. 1. Salah IM. Office microlaparoscopic ovarian drilling (OMLOD) versus conventional laparoscopic ovarian drilling (LOD) for women with polycystic ovary syndrome. Archives Of Gynecology and Obstetrics 2013;287(2):361-7. - PubMed

See 2011 {published data only}

1. 1. See CJ, McCulloch M, Smikle C, Gao J. Chinese herbal medicine and clomiphene citrate for anovulation: a meta-analysis of randomized controlled trials. The Journal of Alternative and Complementary Medicine 2011;17(5):397-405. - PubMed

Shah 2016 {published data only}

1. 1. Shah KN, Patel SS. Phosphatidylinositide 3-kinase inhibition: A new potential target for the treatment of polycystic ovarian syndrome. Pharmaceutical Biology 2016;54(6):975-83. - PMC - PubMed

Shao 2004 {published data only}

1. 1. Shao RY, Lang FJ, Cai JF. Clinical observation on treatment of Stein-Leventhal syndrome caused sterility by combined use of clomiphene and Chinese nourishing shen and activating blood circulation drugs. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2004;24(1):41-3. - PubMed

Shao 2006 {published data only}

1. 1. Shao MX, Zhang XL, Sun JJ, Yan YF. Clinical observation of integration of traditional Chinese medicine and Western medicine in treating infertility caused by PCOS. Journal of Sichuan of Traditional Chinese Medicine 2006;24(1):90-1.

Shen 2008 {published data only}

1. 1. Shen GH. Quyu tiaojing decoction in treating 150 cases of PCOS. Journal of New Chinese Medicine 2008;40(2):82-3.

Shen 2013 {published data only}

1. 1. Shen W, Zhang Y, Li W, Cong J, Zhou Y, Ng EHY, et al. Effects of tanshinone on hyperandrogenism and the quality of life in women with polycystic ovary syndrome: protocol of a double-blind, placebo-controlled, randomised trial. BMJ Open 2013;3(10):e003646. - PMC - PubMed

Sheng 2010 {published data only}

1. 1. Sheng WZ. Clinical study on cycle treatment of polycystic ovary syndrome with Bu Shen Huo Xue method [Master thesis]. Shandong (China): Shandong University of Traditional Chinese Medicine, 2010.

Sheng 2018 {published data only}

1. 1. Sheng XY, Song ML. Cupai Zhuyun Decoction in treatment of kidney deficiency and liver stagnation type of polycystic ovary syn-drome and abnormal ovulation infertility: a clinical observation. Chinese Remedies & Clinics 2018;18(12):2117-9.

Shi 2009a {published data only}

1. 1. Shi Y, Xu WF, Ying XJ, Zhu D. Clinical study on acupuncture combined with kidney yin tonifying herbs for polycystic ovary syndrome of kidney in deficiency. Shanghai Journal of Traditional Chinese Medicine 2009;43(10):33-5.

Shi 2009b {published data only}

1. 1. Shi Y, Feng HJ, Liu HR, Zhu D. Observation on therapeutic effect of acupuncture combined with Chinese herbs on polycystic ovary syndrome of kidney deficiency and phlegm stasis type. Zhongguo Zhen Jiu [Chinese Acupuncture & Moxibustion] 2009;29(2):99-102. - PubMed

Shi 2011 {published data only}

1. 1. Shi Y. Xiao Chai Hu Jia JianTang Treating polycystic ovary syndrome in 40 patients. Zhejiang Journal of Traditional Chinese Medicine 2011;46(2):120.

Shi 2016 {published data only}

1. 1. Shi GL. Clinical study of Yishenhuoxue decoction combined with clomiphene in the treatment of ovulation dysfunction infertility of polycystic ovary syndrome. Maternal & Child Health Care of China 2016;31(20):4243-5.

Shi 2017 {published data only}

1. 1. Shi DY, Zheng YL, Chen SQ, Zhan MG. Clinical Study on Bushen Tiaojing Decoction in Treatment of Infertility Caused by Polycystic Ovary Syndrome. China Journal of Chinese Medicine 2017;32(11):2193-5.

Shi F 2010 {published data only}

1. 1. Shi F, Chen YF. Clinical observation on the combine traditional Chinese and western medicine treatment of 60 patients with polycystic ovarian syndrome. Journal of Changchun University of Traditional Chinese Medicine 2010;26(6):922-3.

Shi LJ 2010 {published data only}

1. 1. Shi LJ. Observation of treatment of kidney weakness and phlegm blocking polycystic ovary syndrome based on method of tonify the kidney and regulating the period of menses with moxibustion [Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2010.

Shu 2012 {published data only}

1. 1. Shu RM. Clinical study on treating polycystic ovary syndrome of liver depression with adjustment of Jia Jian Xiao Yao San and chloramiphene [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2012.

Si 2016 {published data only}

1. 1. Si Q. Integrative therapy of menstrual disorders caused by polycystic ovary syndrome. Practical Electronics Magazine Gynecological Endocrinology 2016;3(2):113-5.

Sohaei 2019 {published data only}

1. 1. Sohaei S, Amani R, Tarrahi M J, Ghasemi-Tehrani H. The effects of curcumin supplementation on glycemic status, lipid profile and hs-CRP levels in overweight/obese women with polycystic ovary syndrome: a randomized, double-blind, placebo-controlled clinical trial. Complementary therapies in medicine 2019;47:Article Number: 102201. - PubMed

Song 2010 {published data only}

1. 1. Song ZL, Xu J, Wang Y. Clinical observation on "Bushen Ruanjian Formula" in treating polycystic ovary syndrome with anovulation. Shanghai Journal of Traditional Chinese Medicine 2010;44(8):47-50.

Song 2011 {published data only}

1. 1. Song ZH, Zhang HM, Zhang XS. Clinical observation of combining traditional Chinese and Western medicine treatment of polycystic ovary syndrome. Chinese Journal of Rehabilitation 2011;26(4):286-7.

Stone 2009 {published data only}

1. 1. Stone JAM, Yoder KK, Case EA. Delivery of a full-term pregnancy after Traditional Chinese Medicine treatment in a previously infertile patient diagnosed with polycystic ovary syndrome. Alternative Therapies In Health And Medicine 2009;15(1):50-2. - PubMed

Su 2012 {published data only}

1. 1. Su SP, Liu YW, Peng M, Gao BZ. Clinical observation on metformin combine with Bu Shen Huo Xue Hua Tan Methods for polycystic ovary syndrome. China Practical Medicine 2012;17(17):159-60.

Sui 2011 {published data only}

1. 1. Sui MF. Treatment of 96 patients with polycystic ovary syndrome of two methods' comparison. Value Engineering 2011;30(7):192.

Sun 2011 {published data only}

1. 1. Sun WF, Liang J, Zhang XX, Feng SM. Clinical research on kidney-tonifying blood-activating and sputum-eliminating therapy for the treatment of polycystic ovary syndrome (PCOS) with insulin resistance (IR). Chinese Archives of Traditional Chinese Medicine 2011;29(9):2018-20.

Sun 2012 {published data only}

1. 1. Sun H, Peng WJ. Clinical observation on combine traditional Chinese and western medicine treat 51 cases of polycystic ovary syndrome with obesity. Xinjiang Journal of Traditional Chinese Medicine 2012;30(3):47-9.

Sun 2014 {published data only}

1. 1. Sun HL. Clinical study of acupuncture odd ovulation disorders through four veins treatment of polycystic ovary syndrome. Yunnan CHinese Medicine College 2014.

Sun C 2010 {published data only}

1. 1. Sun C. Clinical study on the effect of kidney-nourishing and phlegm-resolving method combined with metformin treating polycystic ovary syndrome with insulin resistance [Masters thesis]. Nanjing (China): Nanjing University Of Chinese Medicine, 2010.

Sun FX 2016 {published data only}

1. 1. Sun FX, Wu Y. A study on treating infertility from polycystic ovary syndrome with the Bushen Huoxue decoction plus clomifene. Clinical Journal of Chinese Medicine 2016;8(35):109-10.

Sun J 2009 {published data only}

1. 1. Sun J. Integrated therapy of Chinese and western medicine on 56 patients with infertility caused by PCOS. Chinese Journal of Practical Medicine 2009;36(3):72.

Sun L 2016 {published data only}

1. 1. Sun L. Clinical Study on the follicular development Effect ofcalming heart and nourishing kidney in late menstruationtreating infertile women with polycystic ovary syndrome [Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2016.

Sun W 2010 {published data only}

1. 1. Sun W, Cui W, Li J. Study of the mechanism of electro-acupuncture treatment on PCOS and asthenia of kidney. Chinese Journal of Birth Health and Heredity 2010;18(1):105-7.

Sun Y 2009 {published data only}

1. 1. Sun Y. Combination of Traditional Chinese Medicine and WM (Western medicine) treat sterility of polycystic ovary syndrome. Journal of Zhejiang College of Traditional Chinese Medicine 2009;33(3):344-5.

Talaat 2018 {published data only}

1. 1. Talaat Bassem, Ammar Islam Mohamed Magdi. The added value of cinnamon to metformin in controlling symptoms of polycystic ovary syndrome, a randomized controlled trial. Middle East Fertility Society Journal 2018;23(4):440-5.

Tan 2005 {published data only}

1. 1. Tan MH. Resistant clomiphene sterility with polycystic ovarian syndrome treated by prescription of Chinese traditional medicine benefiting to gravidity and clomiphene. Maternal and Child Health Care of China 2005;20(7):824-5.

Tan 2012 {published data only}

1. 1. Tan L, Tong Y, Sze SCW, Xu M, Shi Y, Song XY, et al. Chinese herbal medicine for infertility with anovulation: a systematic review. Journal of Alternative & Complementary Medicine 2012;18(12):1087-100. - PubMed

Tang 2012 {published data only}

1. 1. Tang CY, Wu YH. Tonifying kidney and removing blood stasis combined with Western medicine treatment for ovulation induction in patients with polycystic ovary syndrome. Journal of Traditional Chinese Medicine University of Hunan 2012;32(6):46,73.

Tao 2003 {published data only}

1. 1. Tao LL, Chen XP, Gu ZT. Study on treatment of polycystic ovarian syndrome with infertility by combined therapy of Chinese herbal medicine and compound cyproterone acetate. Chinese Journal of Integrative Medicine 2003;9(2):98-103.

Tao 2006 {published data only}

1. 1. Tao LL, Zhang YZ, Sang X, Zeng L, Yu AQ, Chen LF. Effects of modified longdan xiegan decoction on hyperandrogenism in patients with polycystic ovary syndrome of stagnant fire in Gan channel type. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2006;26(9):838-41. - PubMed

Tao 2008 {published data only}

1. 1. Tao LL, Long YL, Sang X, Zhang YZ, Chen XP, Niu XY, et al. Effects of point catgut-embedding therapy combined Chinese medicinal herbs of invigorating spleen to remove phlegm on insulin resistance and serum adiponectin level in obese patients with polycystic ovary syndrome. China Journal of Traditional Chinese Medicine and Pharmacy 2008;23(5):434-7.

Tao 2009 {published data only}

1. 1. Tao LL, Fu YH, Xie PP, Wu T, Sang X, Long YL, et al. Effect of acupoint catgut-embedding therapy combined with spleen strengthening and phlegm removing herbs on insulin resistance and adipocyte factors in patients with obese-type polycystic ovary syndrome. Journal of Guangzhou University of Traditional Chinese Medicine 2009;26(2):134-7.

Tao 2010 {published data only}

1. 1. Tao LL, Wang HY, Chen XP, Sang X, Zeng C, Xin J, et al. Effect of point thread-embedding plus herbal decoction for strengthening the spleen to dissolve phlegm on the glucolipide metabolism of the obese patients with polycystic ovary syndrome. Journal of Traditional Chinese Medicine 2010;51(3):239-42.

Tao 2011 {published data only}

1. 1. Tao JF, Lu XH. Chinese medicine cycle therapy for female college students of 30 cases of polycystic ovary syndrome clinical observation. Journal of New Chinese Medicine 2011;43(7):75-7.

Tao 2017 {published data only}

1. 1. Tao HH. Clinical Effects of Zuogui Soothing Liver Decoction on Polycystic Ovary Syndrome Infertility. Chinese General Practice 2017;33(11):1288-9.

Tian 2017 {published data only}

1. 1. Tian Y, Gao XL. Guizhi Fuling Capsule Combined with western medicine in the treatment of polycystic ovarian syndrome and its effect on endocrine metabolism and ovulation. Shaanxi Journal of Traditional Chinese Medicine 2017;38(4):444-5.

Tong 2017 {published data only}

1. 1. Tong XL, Tan Y, Yin YY, Zhou G. Sequential therapy combined with ovulation induction of PCOS in endometrium of infertile women. Chinese Traditional Patent Medicine 2017;39(12):2491-6.

Ulbricht 2016 {published data only}

1. 1. Ulbricht CE, Natural Standard Research Collaboration. An evidence-based systematic review of Yin Yang Huo (Epimedium spp.) by the Natural Standard Research Collaboration. Journal Of Dietary Supplements 2016;13(2):136-64. - PubMed

Ushiroyama 2001 {published data only}

1. 1. Ushiroyama T, Ikeda A, Sakai M, Hosotani T, Suxuki Y, Tsubokura S, et al. Effects of unkei-to, an herbal medicine, on endocrine function and ovulation in women with high basal levels of luteinizing hormone secretion. The Journal of Reproductive Medicine 2001;46(5):451-6. - PubMed

Ushiroyama 2006 {published data only}

1. 1. Ushiroyama T, Hosotani T, Mori K, Yamashita Y, Ikeda A, Ueki M. Effect of switching to Wen-jing-tang (Unkei-To) from preceding herbal preparations selected by eight-principle pattern identification on endocrinological status and ovulatory induction in women with polycystic ovary syndrome. The American Journal of Chinese Medicine 2006;34(2):177-87. - PubMed

Vajda 2013 {published data only}

1. 1. Vajda FJE, Dodd S, Horgan D. Lamotrigine in epilepsy, pregnancy and psychiatry--a drug for all seasons? Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia 2013;20(1):13-6. - PubMed

van Oppen 2015 {published data only}

1. 1. Oppen JD, Daniel PS, Sovani MP. What is the potential role of transcutaneous carbon dioxide in guiding acute noninvasive ventilation? Respiratory Care 2015;60(4):484-91. - PubMed

Wan 2012 {published data only}

1. 1. Wan PF. The clinical study Intherapies of obesity-PCOS by Chinese herbs combined with different frequency of electroacupuncture [Masters thesis]. Shandong (China): Shandong Traditional Chinese Medicine University, 2012.

Wang 2006a {published data only}

1. 1. Wang J, Zhang DX, Cao JM. Clinical observation on Yishen jianpi method combined with metformin in treating PCOS with insulin resistance. Journal of Sichuan of Traditional Chinese Medicine 2006;24(9):67-8.

Wang 2006b {published data only}

1. 1. Wang J, Chen YF, Xu SQ. Observation of integration of traditional Chinese medicine and western medicine in treating infertility caused by PCOS. Public Medical Forum Magazine 2006;10(8B):717-8.

Wang 2011a {published data only}

1. 1. Wang Y. Clinical observation on 45 cases of polycystic ovarian syndrome accompanied with emotional disturbance treated by Shugan Tiaojing formula. Journal of Traditional Chinese Medicine 2012;52(17):1479-82.

Wang 2011b {published data only}

1. 1. Wang Y, Chen Y, Wang X. The effect of Cang-Fu-Dao-Tan decoction on insulin resistance, adiponectin and leptin levels in patients with obese-type polycystic ovarian syndrome. Chinese Archives of Traditional Chinese Medicine 2011;29(11):2256-7.

Wang 2013 {published data only}

1. 1. Wang YR, Li CR. Clinical observation on acupuncture treatment of polycystic ovary syndrome. China Healthcare & Nutrition 2013;23(4):2112.

Wang 2017 {published data only}

1. 1. Wang Y, Gao J S, Cai W Y, Xie L Z, Ma H L, Zhang Y H, et al. Characteristics and obstetrics outcomes of different traditional Chinese medicine syndromes in women with polycystic ovary syndrome: A secondary analysis. Journal of Obstetrics and Gynaecology Research 2017;43 (Supplement 1):155.

Wang 2019 {published data only}

1. 1. Wang Y. Randomized Controlled Study of Bushen Huoxue Recipe combined with Ethinyl Estradiol Cyproterone in the Treatment of Polycystic Ovary Syndrome. Journal of Practical Traditional Chinese Internal Medicine 2019;33(2):48-51.

Wang CX 2016 {published data only}

1. 1. Wang CX, Li YW. Bailing Tiaogan Decoction in Treating Infertilitas Feminis of Liver Qi Stagnation Type Polycystic Ovary Syndrome. Chinese Journal of Experimental Traditional Medical Formulae 2016;22(13):165-8.

Wang JL 2009 {published data only}

1. 1. Wang JL, Zhang ZC. Observation of acupuncture and acupoint catgut-embedding therapy for PCOS patients of obesity. Liaoning Journal of Traditional Chinese Medicine 2009;36(9):1574-5.

Wang LL 2016 {published data only}

1. 1. Wang LL, Yang HW, Wu XK. Acupuncture treatment of polycystic ovary syndrome RCTs syndrome and myofascial trigger point acupoints. Journal of Chinese Medicine 2016;66(8):673-6.

Wang NS 2011 {published data only}

1. 1. Wang NS. GFW modified act on polycystic ovary syndrome in experimental and clinical efficacy of phlegm and blood stasis type [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2011.

Wang Q 2010 {published data only}

1. 1. Wang Q, Li FY. Clinical research of integrated Chinese and western medicine in treating polycystic ovarian syndrome of kidney yang deficiency. Shanghai Journal of Traditional Chinese Medicine 2010;44(12):66-8.

Wang Q 2011 {published data only}

1. 1. Wang Q. Chinese and Western medicine treatment of 60 cases of polycystic ovary infertility. Beifang Yaoxue 2011;8(9):51.

Wang Q 2012 {published data only}

1. 1. Wang Q, Li FY. Nuan Gong Zhu Yun Tang combine with clomiphene citrate for polycystic ovary syndrome (the kidney yang deficiency type) follicular development. Liaoning Journal of Traditional Chinese Medicine 2012;39(9):1752-4.

Wang QH 2012 {published data only}

1. 1. Wang QH, Liu YP, Xie PP, Yang XP, Huang SH, Chen SW, et al. Clinical research of polycystic ovary syndrome treated with non-surgical integrated Chinese and Western medicine. World Journal of Integrated Traditional and Western Medicine 2012;7(11):968-71.

Wang YH 2005 {published data only}

1. 1. Wang YH, Yang YS, Zhang YL. Clinical study of Ganshao capsule in treating clomiphene resistant polycystic ovarian syndrome. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2005;25(8):704-6. - PubMed

Wang YH 2010 {published data only}

1. 1. Wang YH. Combine traditional Chinese and western medicine treatment of infertility caused by polycystic ovary syndrome. China Modern Medicine 2010;17(20):93-4.

Wang YL 2005 {published data only}

1. 1. Wang YL. Clinical observation on Bushen Huoxue Huatan formula in treating PCOS with infertility. Chinese Archives of Traditional Chinese Medicine 2005;23(8):1519-20.

Wei 2008 {published data only}

1. 1. Wei X. Clinical observation of integration of traditional Chinese medicine and western medicine in treating infertility caused by PCOS. Hebei Journal of Traditional Chinese Medicine 2008;30(7):732-4.

Wei 2018 {published data only}

1. 1. Wei AW, Xiao HDZ, Song YL. Clinical efficacy observation of Dingkun Pills combined with clomiphene in the treatment of polycystic ovary syndrome with infertility. Chinese Journal of Practical Gynecology and Obstetrics 2018;34(4):444-7.

Wei CL 2011 {published data only}

1. 1. Wei CL. Chinese herbal compound joint Diane-35 on sex hormone levels in patients with polycystic ovary syndrome. Chinese Journal of Experimental Traditional Medical Formula 2011;17(5):239.

Wei XX 2011 {published data only}

1. 1. Wei XX. Combine traditional Chinese and western medicine in the treatment of polycystic ovary syndrome curative effect observation. Guide of China Medicine 2011;9(29):152-3.

Wei YQ 2011 {published data only}

1. 1. Wei YQ. Clinical observation on combine traditional Chinese and Western medicine for polycystic ovarian syndrome. Seek Medical and Ask the Medicine 2011;9(11):589.

Wong 2017 {published data only}

1. 1. Wong Charlene HL, Cheung William KW, Chung Vincent CH. Is individualised Chinese herbal formula effective in treating oligomenorrhoea and amenorrhoea among female with polycystic ovary syndrome as compared to standardised Chinese herbal formula? Advances in integrative medicine 2017;4(1):40-1.

Wu 2008 {published data only}

1. 1. Wu N. Clinical study on Bushen Huayu Qutan treatment for PCOS. The Chinese Journal of Modern Applied Pharmacy 2008;25(2):167-70.

Wu 2011 {published data only}

1. 1. Wu KE. Random controlled prospective study of the treatment for PCOS by acupuncture and Chinese medicine combined [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2011.

Wu 2016 {published data only}

1. 1. Wu XK, Wang YY, Liu JP, Liang RN, Xue HY, Ma HX, et al. Randomized controlled trial of letrozole, berberine, or a combination for infertility in the polycystic ovary syndrome. Fertility & Sterility 2016;106(3):(1p). - PubMed

Wu 2017 {published data only}

1. 1. Wu H. Evaluation of the effect of Bushen Huoxue Tiaozhou method combined with Clomiphene on infertility caused by polycystic ovary syndrome. Contemporary Medicine Forum 2017;15(15):128-9.

Wu 2019 {published data only}

1. 1. Wu QY, Jiang HQ. Analysis of the effect of acupuncture combined with medicine in the treatment of ovarian cyst syndrome. Healthful Friend 2019;(8):121.

Wu CC 2012 {published data only}

1. 1. Wu CC, Lei P, Ruan YM, Lin XM, Xiong YL, Yang GY. Effects of oral contraceptive pretreatment on controlled ovarian hyperstimulation and outcomes of IVF-ET. Zhonghua Nan Ke Xue [National Journal Of Andrology] 2012;18(7):623-6. - PubMed

Wu D 2012 {published data only}

1. 1. Wu D. Kidney and spleen france with the clinical research of acupuncture on patients with polycystic ovary syndrome kaohsiung signs intervention [Masters thesis]. Heilongjiang (Chian): Heilongjiang University of Chinese Medicine, 2012.

Wu MY 2010 {published data only}

1. 1. Wu MY. Clinical study of combining traditional Chinese and western medicine treatment of polycystic ovary syndrome. Medical Innovation of China 2010;7(34):47-8.

Wuttke 2015 {published data only}

1. 1. Wuttke W, Seidlova-Wuttke D. Herbal medicines for menopausal symptoms. Maturitas Conference: 10th European Congress on Menopause and Andropause; Madrid, Spain 2015;81(1):120.

Wu XY 2010 {published data only}

1. 1. Wu XY, Liang GY, Yao L. Clinical observation on polycystic ovarian syndrome (PCOS) infertility treatment with Chinese herbs combined with clomiphene. Journal of Hubei University of Chinese Medicine 2010;12(2):15-7.

Wu Y 2013 {published data only}

1. 1. Wu Y, Leonard C, Denz E, Haeberle M. The treatment of luteinised unruptured follicle syndrome with Chinese medicine. Journal of Chinese Medicine 2013;Jun(102):5-19.

Wu YY 2013 {published data only}

1. 1. Wu YY. Efficacy catgut embedding treatment of polycystic ovary syndrome. Medical Information 2013;66(20):422.

Xia 2004 {published data only}

1. 1. Xia XJ, Guo CY. Clinical observation of integrated therapy of Chinese and western medicine on 86 patients with infertility caused by PCOS. The Chinese Journal of Human Sexuality 2004;13(7):16-7, 19.

Xia 2007 {published data only}

1. 1. Xia XJ. Treatment on anovulatory infertility induced by polycystic ovary syndrome through supplementing kidney and promoting blood circulation. The Chinese Journal of Human Sexuality 2007;16(10):23-6, 30.

Xia 2011 {published data only}

1. 1. Xia FL, Si YR, Wen YN. Clinical research on Wen Shen Jian Pi Xiao Tan Zhu Yun particles combined clomiphene treatment of polycystic ovary infertility. Shanxi Journal of Traditional Chinese Medicine 2011;32(3):265-7.

Xiao 2014 {published data only}

1. 1. Xiao SF, Xu YY, Zhu LJ, Hu JL. Catgut embedding joint Diane and metformin in obese women with polycystic ovary syndrome in 36 cases. Jiangxi Journal of Traditional Chinese Medicine 2014;45(4):53-5.

Xie 2005 {published data only}

1. 1. Xie GZ, Zhou ZX, Sun QH, Yang MC, Chen WY, Yang J, et al. Tiao jing gu chong tang and clomiphene treats the PCOS with the result that clinical observation of the sterility. Chinese Journal of the Practical Chinese with Modern Medicine 2005;18(10):1538-9.

Xie 2010 {published data only}

1. 1. Xie XY. Clinical observation of combining traditional Chinese and western medicine treatment of polycystic ovary syndrome. Guide of China Medicine 2010;8(34):103-4.

Xie 2012 {published data only}

1. 1. Xie JH, Gao YM, Han R, Zhang Y. Yin-nourishing and heat-clearing therapy for 30 cases of polycystic ovary syndrome. World Chinese Medicine 2012;7(5):410-2.

Xin, 2019 {published data only}

1. 1. Xin XL, Yuan SF, Guan JZ. Clinical Observation on Bushen Tiaojing Decoction Combined with Letrozole in the Treatment of Infertility Caused by Kidney Deficiency and Liver Depression Type Polycystic Ovarian Syndrome. Chinese Medicine Modern Distance Education of China 2019;17(12):101-3.

Xiong 2012 {published data only}

1. 1. Xiong XL. Treatment effect observation 115 cases patients with polycystic ovary syndrome. Chinese Journal of Clinical Rational Drug Use 2012;5(13):59-60.

Xiong 2018 {published data only}

1. 1. Xiong W, Xiao XY. Analysis of the effect of the combination of traditional Chinese and Western Medicine on infertility caused by polycystic ovary syndrome. Modern Diagnosis & Treatment 2018;29(18):2872-3.

Xu, 2019 {published data only}

1. 1. Xu JH, Cai PP, Sha J. Effect of modified Jiawei Qigong pill and drospirone ethynestradiol tablets pretreatment on endometrial receptivity of infertile patients with kidney deficiency and phlegm-dampness polycystic ovarian syndrome. Hebei Journal of Traditional Chinese Medicine 2019;41(1):36-41.

Xu 2009 {published data only}

1. 1. Xu F. The efficacy of Guishen pill in treating 40 cases of PCOS. Jiangxi Journal of Traditional Chinese Medicine 2009;40(7):36-7.

Xu 2012 {published data only}

1. 1. Xu LF. The clinical research of two Chentang traditional Chinese medicine combined cycle therapy treatment for obese type polycystic ovarian syndrome [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2012.

Xu 2018 {published data only}

1. 1. Xu YJ, Jin XN, Xue YD. Effects of different Chinese medicine prescriptions treating at different stages of menstrual cycle on ovarian function and pregnancy in infertile women with polycystic ovary syndrome. Chinese Journal of General Practice 2018;16(4):626-9.

Xu 2019 {published data only}

1. 1. Xu JH, Cai PP, Sha J. Effect of modified Jiawei Qigong pill and drospirone ethynestradiol tablets pretreatment on endometrial receptivity of infertile patients with kidney deficiency and phlegm-dampness polycystic ovarian syndrome. Hebei Journal of Traditional Chinese Medicine 2019;41(1):36-41.

Xu BH 2016 {published data only}

1. 1. Xu BH, Li MQ, Chen CL, Luo YJ. Effects of Traditional Chinese Medicine periodic therapy on sex hormone, glucose and lipid metabolism of patients with polycystic ovary syndrome. Chinese Journal of Information on Traditional Chinese Medicine 2016;23(1):35-8.

Xu DW 2010 {published data only}

1. 1. Xu DW. Observation on clinical efficacy of Chinese and Western medicine combined with acupuncture in treating PCOS with infertility. Journal of Sichuan of Traditional Chinese Medicine 2010;28(1):93-4.

Xue 2004 {published data only}

1. 1. Xue XW, Wang N. Observation on efficacy of Traditional Chinese Medicine combined with ultrasound in treating 56 cases of PCOS. Chinese General Practice 2004;7(11):828.

Xu HO 2008 {published data only}

1. 1. Xu HO, Luo YL. The application of Zishen yutai pill in ovulation inducing of PCOS. Chinese Journal of Information on Traditional Chinese Medicine 2008;15(5):68.

Xu JH 2008 {published data only}

1. 1. Xu JH. 30 cases of polycystic ovary syndrome treated in Chinese medicine combined with Diane-35. Journal of Henan University of Chinese Medicine 2008;23(2):46-7.

Xu QZ 2016 {published data only}

1. 1. Xu QZ. Observation on therapeutic effect of kidney Activating Blood Herbs on polycystic ovary syndrome of kidney deficiency and blood stasis type. Chinese Journal of Modern Drug Application 2016;10(10):249-50.

Xu RQ 2017 {published data only}

1. 1. Xu RQ, Lin S. Danzhi Xiaoyao Pill in the treatment of 30 cases of polycystic ovary syndrome. Fujian Journal of Traditional Chinese Medicine 2017;48(2):23-4.

Xu SQ 2010 {published data only}

1. 1. Xu SQ. Effects of Bushenshugan method on hyperandrogenism and hyperinsulinemia in poIycystic ovary syndrome [Masters thesis]. Hubei (China): Hubei University of Chinese Mdeicine, 2010.

Xu ZZ 2017 {published data only}

1. 1. Xu ZZ. Observation on curative effect of integrated traditional Chinese and western medicine on infertility of polycystic ovary syndrome. China Medical Engineering 2017;25(6):71-3.

Yan 2003 {published data only}

1. 1. Yan YF, Feng XS, Jiang MF. Clinical observation on Bushen Huoxue herbal medicine in treating 32 cases of PCOS with infertility. Journal of Traditional Chinese Medicine 2003;44(1):39-40.

Yan 2005 {published data only}

1. 1. Yan YF, Yan L. Clinical observation on 30 cases of polycystic ovarian syndrome treated by Bushen Huoxue oral liquid plus metformin. Journal of Traditional Chinese Medicine 2005;46(9):480-2.

Yan 2012 {published data only}

1. 1. Yan XJ. Clinical observation on combine traditional Chinese and western medicine treat 30 cases of polycystic ovary syndrome with infertility. Guiding Journal of Traditional Chinese Medicine and Pharmacology 2012;18(5):53-4.

Yang 2005 {published data only}

1. 1. Yang YH, Hong JY, Wei DY, Chen XM, Lin J. Acupuncture on polycystic ovarian syndrome-induced infertility. Journal of Guangdong Medical College 2005;23(4):377-8.

Yang 2008 {published data only}

1. 1. Yang L, Qi B, Song JX, Hou LH, Wu XK. Detection and analysis of apoptosis related genes of insulin resistance granular cells induced by the traditional Chinese medicine by DNA microarray. Science & Technology Review 2008;26(16):42-6.

Yang 2011 {published data only}

1. 1. Yang ZC. Clinical observation on Zi Ni Wen Shen Tiao Jing Tang treatment of polycystic ovary syndrome. Chinese Journal of Misdiagnostics 2011;11(34):8377.

Yang 2015 {published data only}

1. 1. Yang B-Z, Cui W, Li J. Effects of electroacupuncture intervention on changes of quality of ovum and pregnancy out- come in patients with polycystic ovarian syndrome. Zhen Ci Yan Jiu [Acupuncture Research] 2015;40(2):151-6. - PubMed

Yang 2017a {published data only}

1. 1. Yang HP, Li WL. Study on effect of Yishen Cupai Decoction combined with clomiphene in treating infertility of polycystic ovary syndrome. Laboratory Medicine and Clinic 2017;14(5):645-7.

Yang 2017b {published data only}

1. 1. Yang HP. Clinical observation on the treatment of infertility caused by polycystic ovary syndrome with kidney deficiency and liver depression by the combination of traditional Chinese and Western Medicine [Masters thesis]. Anhui (China): Anhui University of Chinese Medicine, 2017.

Yang D 2014 {published data only}

1. 1. Yang D. Effect of acupuncture and clomiphene citrate for kidney deficiency PCOS infertile women ovulation rate and pregnancy rate. Hunan University of Traditional Chinese Medicine.

Yang GM 2010 {published data only}

1. 1. Yang GM. Clinical observation of combining traditional Chinese and Western medicine treatment of polycystic ovary syndrome. Journal of Clinical and Experimental Medicine 2010;9(17):1331-2.

Yang H 2014 {published data only}

1. 1. Yang H. Traditional Chinese medicine for the treatment of kidney and blood stasis 35 cases of polycystic ovary syndrome. Global Chinese Medicine 2014;7(5):382-4.

Yang JB 2010 {published data only}

1. 1. Yang JB, Xu PL, Yao F, Yang XY. In: Combine traditional Chinese and western medicine clinical observation for the treatment of ovulation disorder polycystic ovary syndrome. Association of Chinese Medicine Gynecology Branch of the Tenth National Gynecologic Academic Conference. 2010.

Yang LF 2017 {published data only}

1. 1. Yang LF. Clinical observation on the treatment of infertility with polycystic ovary syndrome by promoting the discharge of traditional Chinese Medicine. Journal of Practical Gynecologic Endocrinology 2017;4(22):103.

Yang P 2010 {published data only}

1. 1. Yang P. Curative effect observation of combining traditional Chinese and Western medicine treatment of polycystic ovary syndrome. Journal of Guiyang College of Traditional Chinese Medicine 2010;32(5):43-4.

Yang Y 2016 {published data only}

1. 1. Yang Y, Huang FX. Clinical effect of kuntai capsule and letrozole tablets in the internal secretion and ovulation for patients with polycystic ovarian syndrome. China Modern Doctor 2016;54(26):1-3,8.

Yang YQ 2016 {published data only}

1. 1. Yang YQ. Clinical observation on the treatment of polycystic ovarian syndrome infertility by acupoint application combined with traditional Chinese Medicine [Masters thesis]. Shanghai (China): Shanghai University of Traditional Chinese Medicine, 2016.

Yao 2011 {published data only}

1. 1. Yao FW. Clinical Research on the method of kidney-nourishing and phlegm-resolving method combined with Diane-35 on the effects of polycystic ovary syndrome with the high testosterone [Masters thesis]. Heilongjiang (China): Heilongjiang University of Chinese Medicine, 2011.

Yao XY 2012 {published data only}

1. 1. Yao XY, Feng YL, Tang S. Combine traditional Chinese and Western medicine treatment the clinical effect of the treatment of infertility caused by polycystic ovary syndrome. Health Must Read Magazine 2012;11(10):31-2.

Yao Y 2012 {published data only}

1. 1. Yao Y. Clinical study on polycystic ovary syndrome accompanied anovulation by invigorating kidney and activating blood circulation and regulating chong drink [Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2012.

Ye 2004 {published data only}

1. 1. Ye LQ. Chinese periodical therapy combined with metformin in treating 62 cases with PCOS. Jiangxi Journal of Traditional Chinese Medicine 2004;35(5):22-3.

Ye 2010 {published data only}

1. 1. Ye TZ, Cao LQ, Ye CC, Zhang QR, Shen XL, Guo M, et al. Combine traditional Chinese and Western medicine treatment of insulin resistance of 40 cases of polycystic ovary syndrome were observed. Zhejiang Journal of Traditonal Chinese Mdecine 2010;45(4):287.

Ye 2015 {published data only}

1. 1. Ye LQ. Traditional Chinese Mdeicine periodic therapy with metformin efficacy of 120 cases of pubertal polycystic ovary syndrome. Journal of Heilongjiang Traditional Chinese Medicine 2015;44(6):17-8.

Ye 2017 {published data only}

1. 1. Ye WT. Treatment mechanism of infertility of polycystic ovary syndrome by traditional Chinese medicine under morphology. Nei Mongol Journal of Traditional Chinese Medicine 2017;36(3):6-7.

Ye 2018 {published data only}

1. 1. Ye QF. Clinical Study of Acupuncture Combined with Yishen Huatan Huoxue Formula in the Treatment of PCOS. Information on Traditional Chinese Medicine 2018;35(1):104-7.

Ye HJ 2012 {published data only}

1. 1. Ye HJ, Jiang TJ, Li AP, Yv Y. Clinical observation on treating polycystic ovary syndrome with sterility with Guizhifulin capsule and Diane-35 and clomiphene citrate. Chinese Journal of Clinical Pharmacology and Therapeutics 2012;17(6):691-5.

Ye YY 2012 {published data only}

1. 1. Ye YY. Combine traditional Chinese and western medicine treatment of polycystic ovary syndrome curative effect analysis. The Journal of Medical Theory and Practice 2012;25(5):560-2.

Yi 2012 {published data only}

1. 1. Yi LL. Clinical research of gubenquyu decoction in treating PCOS of Qi deficiency and phlegm and blood stasis type [Masters thesis]. Hubei (China): Hubei University of Chinese Medicine, 2012.

Yi 2017 {published data only}

1. 1. Yi HL. Observation on the therapeutic effect of wenshenhuatantiaojing recipe combined with dianing-35 on PCOS of kidney deficiency and phlegm dampness type. Guiyang College of Chinese Meicine 2017.

Yin 2007 {published data only}

1. 1. Yin XP. Laparoscopy combined with Traditional Chinese Medicine in treating PCOS. Reproduction and Contraception 2007;27(7):484-5.

Ying L 2016 {published data only}

1. 1. Ying L, Ying XY, Shi L, Jin Y. Effect of Guashi dectoction combined with letrozole on LH, FSH and E2 in infertile women with polycystic ovary syndrome. Chinese Journal of Biochemical Pharmaceutics 2016;36(3):113-5.

Ying Z 2016 {published data only}

1. 1. Ying Zhang, Jin Sun, Yun-Jiao Zhang, Qian-Yun Chai, Kang Zhang, Hong-Li Ma, et al. The effect of berberine on insulin resistance in women with polycystic ovary syndrome: detailed statistical analysis plan (SAP) for a multicenter randomized controlled trial. Trials 2016;17:(5p). - PMC - PubMed

Yu 2013 {published data only}

1. 1. Yu L, Liao Y, Wu H, Zhao J, Wu L, Shi Y, et al. Effects of electroacupuncture and Chinese kidney-nourishing medicine on polycystic ovary syndrome in obese patients. Chung i Tsah Chih Ying Wen Pan [Journal of Traditional Chinese Medicine] 2013;33(3):287-93. - PubMed

Yu 2015 {published data only}

1. 1. Yu LJ. Traditional Chinese Medicine (yi xu huo wang) versus western medicine to treat women with polycystic ovary syndrome. Modern Journal of Integrated Traditional Chinese and Western Medicine 2015;24(11):1206-8.

Yu 2018 {published data only}

1. 1. Yu LX, Liu N. Clinical treatment of infertility caused by polycystic ovary syndrome. China Health Care & Nutrition 2018;28(29):152-3.

Yu 2019 {published data only}

1. 1. Yu F, Qin XY, Zhang XM, Fu C. Clinical Observation on the Treatment of 52 Cases of Polycystic Ovary Syndrome with Zishen Huatan Zhuyun Decoction and Kuntai Capsule. Journal of Clinical Research 2019;36(6):1162-4.

Yuan 2011 {published data only}

1. 1. Yuan Q. Clinical research of AMH during the process of stimulation period of PCOS as well as the kidney sand sequential Chinese medicine [Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2011.

Yuan 2016 {published data only}

1. 1. Yuan YH, Han YM, Li JX, Hai X. Clinical study on 60 cases of infertility of polycystic ovary syndrome treated with acupuncture and medicine. Chinese Journal of Basic Medicine in Traditional Chinese Medicine 2016;22(7):962-4.

Yuan 2018 {published data only}

1. 1. Yuan QQ. Effect of traditional Chinese medicine combined with Clomiphene on patients with polycystic ovary syndrome. Diet Health 2018;5(12):81-2.

Yv 2011 {published data only}

1. 1. Yv W. Clinical research on combination Chinese medicine and acupuncture in treating polycystic ovarian syndrome [Masters thesis]. Heilongjiang (China): Heilongjiang University of Chinese Medicine, 2011.

Zeng 2007 {published data only}

1. 1. Zeng BF, Xu AF. Clinical observation on pregnancy prompting decoction combined with clomiphene in treating infertility induced by PCOS. China Medical Herald 2007;4(12):68-9.

Zeng 2012 {published data only}

1. 1. Zeng L, Zeng C, Tao LL. Comparative study on Chinese medical syndrome typing and treatment combined different surgical methods for treating clomiphene-resistant polycystic ovary syndrome. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2012;32(11):1492-5. - PubMed

Zhang 2007a {published data only}

1. 1. Zhang H, Ran MX, Chen Q, Tai GX, Song ZH. An experimental research on the expression of endometrial calcitonin affected by Bushen huoxue Chinese herbs. Chinese Journal of Family Planning 2007;15(3):171-3.

Zhang 2009 {published data only}

1. 1. Zhang QM, Sun ZY, Chen X, Yuan JL. Clinical effect observation on treatment to 52 polycystic ovarian syndromes by YUAN-clan zishen huoxue decoction. Journal of Liaoning University of Traditional Chinese Medicine 2009;11(6):151-2.

Zhang 2011a {published data only}

1. 1. Zhang N. Effect of invigorating kidney and removing phlegm herbs on women with polycystic ovary syndrome undergoing in vitro fertilization and embryo transplantation treatment. Journal of Liaoning University of Traditional Chinese Medicine 2011;13(7):56-8.

Zhang 2011b {published data only}

1. 1. Zhang N. Clinical observation of infertile patients with polycystic ovary syndrome treating with Qigongwan and immature follicle puncture technique through ultrasound. Chinese Imaging Journal of Integrated Traditional and Western Medicine 2011;9(3):202-3.

Zhang 2015a {published data only}

1. 1. Zhang T. Effect of Qingre Yangyin recipe on endocrine and metabolism of polycystic ovary syndrome patients. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal Of Integrated Traditional And Western Medicine] 2015;35(10):1175-80. - PubMed

Zhang 2015b {published data only}

1. 1. Zhang T. Affect the patient's endocrine and metabolic heat and nourishing on polycystic ovary syndrome. Journal of Chinese Medicine 2015;(10):1175-80. - PubMed

Zhang 2015c {published data only}

1. 1. Zhang T, Guo JY. Effects of Lycii Cortex on express of PI3K/PKB in PCOS rats. Zhongguo Zhong Yao Za Zhi [China Journal Of Chinese Materia Medica] 2015;40(10):2004-8. - PubMed

Zhang 2016 {published data only}

1. 1. Zhang YL. Clinical observation on treatment of PCOScaused sterility by combined ClomipheneCitrate and Bushenhuayufang [Masters thesis]. Gansu (China): Gansu University of Chinese Medicine, 2016.

Zhang 2019a {published data only}

1. 1. Zhang CL, Liu ZJ. Effects of Multi-phase Administration of Bushen Tiaojing Decoction on Ovulation Outcomes, Symptoms and Sex Hormone Levels in Patients with Polycystic Ovary Syndrome. World Chinese Medicine 2019;14(4):970-3.

Zhang 2019b {published data only}

1. 1. Zhang CL, Liu ZJ. Effects of Multi-phase Administration of Bushen Tiaojing Decoction on Ovulation Outcomes, Symptoms and Sex Hormone Levels in Patients with Polycystic Ovary Syndrome. World Chinese Medicine 2019;14(4):970-3.

Zhang FC 2007 {published data only}

1. 1. Zhang FC. Effect of qingfei jianpi xiaocuo decoction for the treatment of acne in polycystic ovary syndrome: an observation of 46 cases. Journal of New Chinese Medicine 2007;39(9):34-5.

Zhang H 2007b {published data only}

1. 1. Zhang H. Research on Chinese herbal medicine combined with Western medicine in treating 40 cases of PCOS. Journal of Changchun University of Traditional Chinese Medicine 2007;23(5):68-9.

Zhang H 2010 {published data only}

1. 1. Zhang H. Clinical observation on traditional Chinese and western medicine for polycystic ovary combine. Asia-Pacific Traditional Medicine 2010;6(9):126-7.

Zhang H 2014 {published data only}

1. 1. Zhang H, Ma Y, Wang ZL, Gao QQ. Treating 35 cases of polycystic ovary syndrome infertility in the integrative medicine. Clinical Journal of Chinese Medicine 2014;6(7):33-4, 6.

Zhang HH 2011 {published data only}

1. 1. Zhang HH, Cui XP. Combine traditional Chinese and western medicine treatment of 20 patients with polycystic ovary syndrome. Modern Traditional Chinese Medicine 2011;31(4):12-3.

Zhang HM 2011 {published data only}

1. 1. Zhang HM, Tan Y. Clinical study on therapy of nourishing yin and supplementing yang in decreasing androgen level of polycystic ovary syndrome patients with kidney asthenia. Journal of New Chinese Medicine 2011;43(1):50-2.

Zhang J 2011 {published data only}

1. 1. Zhang J, Qin JQ. Combine traditional Chinese and Western medicine in the treatment of infertility caused by polycystic ovary syndrome. Journal of Qiqihae University of Medicine 2011;32(5):320.

Zhang JH 2018 {published data only}

1. 1. Zhang JH, Xia HQ, Wang P. Observation on the effect of traditional Chinese medicine combined with acupuncture on infertility of polycystic ovary syndrome. Bao Jian Wen Hui 2018;(4):42.

Zhang JJ 2012 {published data only}

1. 1. Zhang JJ. Clinical observation of traditional Chinese medicine combined with dyne - 35 for polycystic ovary syndrome. Journal of Guangxi Traditional Chinese Medical University 2012;15(2):16-7.

Zhang JX 2015 {published data only}

1. 1. Zhang JX. Efficacy of integrative medicine polycystic ovarian syndrome. Modern Journal of Integrated Traditional Chinese and Western Medicine 2015;24(14):1562-3.

Zhang L 2010 {published data only}

1. 1. Zhang L, Liu ZD, Ren YM. From the traditional Chinese medicine ovulation decoction in treatment of polycystic ovary syndrome, 96 cases of clinical observation. Inner Mongol Journal of Traditional Chinese medicine 2010;29(18):19-20.

Zhang LM 2003 {published data only}

1. 1. Zhang LM, Hou LH. Clinical observation on Bushen decoction combined with acupuncture in treating PCOS. Journal of Clinical Acupuncture and Moxibustion 2003;19(4):23-4.

Zhang LX 2012 {published data only}

1. 1. Zhang LX. The influence of Cang Fu Dao Tan Tang Jia Jian decoction on endocrine and glucose metabolism of polycystic ovary syndrome patients with insulin resistance [Masters thesis]. Zhejiang (China): Zhejiang Chinese Medical University, 2012.

Zhang M 2010 {published data only}

1. 1. Zhang M. Clinical study on the "JiaJian Wu Ji San" effect of phlegm-dampness type of polycystic ovary syndrome [Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2010.

Zhang MM 2003 {published data only}

1. 1. Zhang MM, Huang GY, Lu FE, Paulus WE, Sterzik K. Treatment of polycystic ovary syndrome with clomiphene resistance patients by herbs combined with clomiphene. Chinese Journal of the Practical Chinese with Modern Medicine 2003;3(16):157-9.

Zhang Q 2010 {published data only}

1. 1. Zhang Q. A clinic study of health-related quality-of-life in polycystic ovary syndrome and the impact of Traditional Chinese Medicine method with invigorating kidney, dissipating phlegm and promoting blood flow [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2010.

Zhang SM 2018 {published data only}

1. 1. Zhang SM, Han YF. Effects of Quyu Huatan Decoction Combined with Ovulation Promotion Scheme on Proteins Related to Insulin Signaling Pathway in Patients with Polycystic Ovarian Syndrome. World Chinese Medicine 2018;13(10):2417-20.

Zhang T 2010 {published data only}

1. 1. Zhang T. Polycystic ovary syndrome treated with Chinese medicine "Culuan Pill". Journal of Zhejiang University of Traditional Chinese Medicine 2010;34(4):515-6.

Zhang TH 2011 {published data only}

1. 1. Zhang TH. Clinical analysis of diagnosis and treatment of 118 cases of patients with polycystic ovary syndrome. Journal of China Traditional Chinese Medicine Information 2011;3(20):230.

Zhang TY 2012 {published data only}

1. 1. Zhang TY, Wang Q. Phlegm, blood stasis by method of clinical trials for the treatment of ovulation disorder polycystic ovary syndrome. Modern Traditional Chinese Medicine 2012;32(2):28-9.

Zhang XY 2014 {published data only}

1. 1. Zhang XY. Traditional Chinese Mdeicine and Western medicine treatment of insulin resistance in polycystic ovary syndrome patients with clinical observation. Health Digest 2014;66(8):189-90.

Zhang Y 2007 {published data only}

1. 1. Zhang Y, Tu RQ, Tu DJ. The clinical effects of Diane-35 with Chinese traditional medicine in polycystic ovary syndrome therapy. Clinical Medical Journal of China 2007;14(5):711-2.

Zhang YH 2012 {published data only}

1. 1. Zhang YH, Peng X, Liu XF, Zhang YL, Zhang JS, Xu DJ, et al. Chinese medicine internal and external washing treatment late onset acne with high androgen hematic disease related analysis. Practical Clinical Journal of Integrated Traditional Chinese and Western Medicine 2012;12(6):1-2.

Zhao 2006a {published data only}

1. 1. Zhao Y, Wang YP, Ding QL, Guan HY, Chen M. [Clinical research of acupoint injection of HMG in treating PCOS with infertility]. Clinical Medicine of China 2006;22(8):748-9.

Zhao 2006b {published data only}

1. 1. Zhao Y. Clinical observation on acupoint injection in treating PCOS with infertility. Liaoning Journal of Traditional Chinese Medicine 2006;33(1):101-2.

Zhao 2007 {published data only}

1. 1. Zhao YL, Li XH, Wen LJ. Observation the effect of polycystic ovarian syndrome by combination treatment of Chinese traditional and western medicine by ultrasonogram. China Practical Medicine 2007;2(17):22-3.

Zhao 2009 {published data only}

1. 1. Zhao H, Bao WF, Zhang T. Advantages of Chinese medicine for treatment of blood sugar and lipid metabolic disorders in patients with polycystic ovarian syndrome. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2009;29(7):595-8. - PubMed

Zhao 2014 {published data only}

1. 1. Zhao Y, Du B, Jiang X, Ma M, Shi L, Zhang Q, et al. Effects of combining lowdose aspirin with a Chinese patent medicine on follicular blood flow and pregnancy outcome. Molecular Medicine Reports 2014;10(5):2372-6. - PubMed

Zhao 2016 {published data only}

1. 1. Zhao CJ, Jiang H, Zhuang CX. Efficacy of polycystic ovary syndrome new BREE Dodder pills. Journal of New Chinese Medicine 2016;66(02):148-51.

Zhao 2019 {published data only}

1. 1. Zhao AL. Clinical observation on 39 cases of infertility with polycystic ovary syndrome of phlegm dampness type treated by combination of traditional Chinese and Western Medicine. Chinese Journal of Ethnomedicine and Ethnopharmacy 2019;28(4):101-3.

Zhao CP 2006 {published data only}

1. 1. Zhao CP. Chinese herbal medicine combined with Western medicine in treating PCOS. Journal of Shanxi College of Traditional Chinese Medicine 2006;7(6):44-5.

Zhao H 2008 {published data only}

1. 1. Zhao H, Wang XE, Bao WF. The effect of metabolic status of blood sugar and lipid and reproductive endocrine of Chinese traditional medicine. Journal of Zhejiang University of Traditional Chinese Medicine 2008;32(4):458-60.

Zhao HB 2008 {published data only}

1. 1. Zhao HB, He YR. Clinical observation of effect of clomiphene citrate combined with cassia tuckahoe capsule on infertile polycystic ovary syndrome patient. China Tropical Medicine 2008;8(11):1942-3.

Zhao J 2010 {published data only}

1. 1. Zhao J. The clinical observation of the effects of ovulation induction in stimulation cycles of PCOS by sequential therapy of nourishing-yin and supplementing-yang [Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2010.

Zhao XL 2010 {published data only}

1. 1. Zhao XL, Wang X. Combine traditional Chinese and Western medicine treatment of polycystic ovary syndrome clinical observation to infertility. Journal of Changzhi Medical College 2010;24(2):136-8.

Zhao Y 2008 {published data only}

1. 1. Zhao Y, Huang CL, Ding QL, Wang YP, Chen M. [Influence and efficacy of acupoint injection on endometrium and sexual hormone in PCOS patients]. Lishizhen Medicine and Materia Medica Research 2008;19(10):2400-1.

Zheng 2011 {published data only}

1. 1. Zheng CC. Phlegm act joint metformin treatment of kidney phlegm type PCOS with IR clinical observation [Masters thesis]. Hubei (China): Hubei University of Chinese Medicine, 2011.

Zheng 2011a {published data only}

1. 1. Zheng YX. Therapeutic effects on renal deficiency type of polycystic ovary syndrome with the periodic therapy of traditional Chinese medicine [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2011.

Zheng 2011b {published data only}

1. 1. Zheng YX. The observation of Clinical Efficacy in treating polycystic ovary syndrome by traditional Chinese medicine and Western medicine. Journal of Traditional Chinese Medicine University of Hunan 2011;31(12):23-4.

Zheng 2014a {published data only}

1. 1. Zheng YX. Clinical observation of Longdan Xiegan decoction and Bushen Huatan decoction in the treatment of polycystic ovary syndrome. Chinese Journal Of Family Planning & Gynecotokology 2014;6(6):40-3.

Zheng 2014b {published data only}

1. 1. Zheng YX. [Integrative medicine clinical observation ovulatory disorder infertility]. Journal of Inner Mongolia Traditional Chinese Medicine 2014;66(22):67-8.

Zheng 2018 {published data only}

1. 1. Zheng SJ, Xu Y. Effect of Bushen Tiaojing Decoction assisted in treating infertility caused by polycystic ovary syndrome with kidney deficiency and blood stasis and its effect on hormone level. Chinese Journal Of Family Planning & Gynecotokology 2018;10(1):63-6.

Zheng GJ 2011 {published data only}

1. 1. Zheng GJ, Pan P. Curative effect observation of combining traditional Chinese and Western medicine treatment of polycystic ovary syndrome. Guangming Journal of Chinese Medicine 2011;26(12):2518-9.

Zheng SJ 2015 {published data only}

1. 1. Zheng SJ, Ding JZ, Li Y. Integrative treatment of polycystic ovary syndrome efficacy. Practical Electronics Journal Gynecological Endocrinology 2015;(9):86, 91.

Zheng XH 2015 {published data only}

1. 1. Zheng XH, Zhao XD. Observation of infertility with polycystic ovarian syndrome treated by combination of Pailuan decoction and Clomifene citrate. Hebei Journal of Traditional Chinese Medicine 2015;37(1):58-60.

Zhi 2012 {published data only}

1. 1. Zhi J. Clinical observation of Diane-35, metformin combined with Chinese "Bushen Huoxue Tiaozhou therapy" in treatment of polycystic ovary syndrome [Masters thesis]. Hubei (China): Hubei University of Chinese Medicine, 2012.

Zhong 2006 {published data only}

1. 1. Zhong XL, Zhuo XY, Zhang FC, Zhang Z. Effective observation on nourishing kidney herbal medicine in treating 72 PCOS. China and Foreign Medical Journal 2006;4(7):55-7.

Zhong 2008 {published data only}

1. 1. Zhong XL, Cao DN, Lin WX, Zhang Z, Zheng QY. [Clinical research of Chinese herbal medicine in treating 82 cases with PCOS]. Journal of New Chinese Medicine 2008;40(11):58-9.

Zhong 2012 {published data only}

1. 1. Zhong GT. The curative effect of Bushen Huoxue decoction to stimulate ovulation in treating polycystic ovary syndrome. Medical Recapitulate 2012;18(2):306-7.

Zhong 2016 {published data only}

1. 1. Zhong CH, Liang BZ. Clinical effect of traditional Chinese medicine combined with acupuncture and moxibustion on polycystic ovary syndrome with infertility. Strait Pharmaceutical Journal 2016;28(7):180-1.

Zhong XC 2009 {published data only}

1. 1. Zhong XC, Chen QX, Zhang J, Li XB. Clinical observation of shenqi capsule in treating polycystic ovary syndrome. Journal of Liaoning University of Traditional Chinese Medicine 2009;11(3):118-20.

Zhong XL2009 {published data only}

1. 1. Zhong XL, Cao DN, Lin WX, Zheng QY, Zhang Z. [Clinical research of Yugui pill in treating PCOS with insulin resistance]. Traditional Chinese Medicine Journal 2009;8(3):50-2.

Zhou 1996 {published data only}

1. 1. Zhou P, Zhou XC, Liu ML. Analysis of result of western medicine combined with or without Traditional Chinese Medicine in treating PCOS. Practical Woman and Child Health 1996;7(4):30-1.

Zhou 2010a {published data only}

1. 1. Zhou YH, Huang YJ, Liu W, Yv H. Clinical research on combined therapy of traditional Chinese and Western medicine on polycystic ovarian syndrome. Liaoning Journal of Traditional Chinese Medicine 2010;37(7):1328-30.

Zhou 2010b {published data only}

1. 1. Zhou YH, Tan Y. Clinical study on treatment of 21 cases of Stein-Leventhal syndrome with laparoscopic ovarian drilling combined with Chinese medications. Jiangsu Journal of Traditional Chinese Medcine 2010;42(9):27-8.

Zhou 2016 {published data only}

1. 1. Zhou J. Clinical Study of Using Bushen Huoxue Chinese Herbs in the Treatment of Poly Cystic Ovary Syndrome Lead to Ovulation Dysfunction Infertility. Journal of Sichuan Traditional Chinese Medicine 2016;34(10):88-90.

Zhou F 2015 {published data only}

1. 1. Zhou F. 40 patients in the combination therapy of polycystic ovary syndrome. Journal Of Medicine Information 2015;(13):219-20.

Zhou FB 2014 {published data only}

1. 1. Zhou FB, Xu YL, Du CC. Self prescription treatment of infertility polycystic ovary syndrome phlegm observation of 40 cases. Chinese Journal of Convalescent Medicine 2014;(6):519-20.

Zhou JH 2012 {published data only}

1. 1. Zhou JH, Wang ZJ, Wang DJ, Gao WL. Clinical observation of combined acupuncture and herbs in treating polycystic ovary syndrome. Shanghai Journal of Traditional Chinese Medicine 2012;46(5):72-4.

Zhou LL 2012 {published data only}

1. 1. Zhou LL. The spleen for eliminating dampness treatments for wet filled the spleen deficiency polycystic ovarian syndrome clinical observation [Masters thesis]. Heilongjiang (China): Heilongjiang University of Chinese Medicine, 2012.

Zhou M 2015 {published data only}

1. 1. Zhou M, Zheng L. Hyperandrogenism clinical observation on 54 cases of integrative medicine polycystic ovary syndrome. Journal of Traditional Chinese Medicine 2015;66(02):75-6.

Zhou MS 2018 {published data only}

1. 1. Zhou MS, Zhou SH. Clinical Observation on of Chinese Herbal Medicine Combined with Acupuncture in Treating Polycystic Ovary Syndrome Complicated with Infertility. Guangming Journal of Chinese Medicine 2018;33(7):966-8.

Zhou WQ 2018 {published data only}

1. 1. Zhou WQ, Fang DZ. Clinical observation of Tiaojing Cuyun Pills combined with clomifene in treatment of obesity polycystic ovarian syndrome infertility. Drugs & Clinic 2018;33(4):926-9.

Zhou XL 2012 {published data only}

1. 1. Zhou XL. The sterility of polycystic ovary syndrome treatment analysis. Chinese Manipulation & Rehabilitation Medicine 2012;3(12):177-8.

Zhou XY 2012 {published data only}

1. 1. Zhou XY. Clinical study on treatment of polycystic ovary syndrome with Yi-Jing-Bu-Shen decoction [Masters thesis]. Shandong (China): Shandong University of Traditional Chinese Medicine, 2012.

Zhou YX 2014 {published data only}

1. 1. Zhou YX. Clinical research on combined traditional Chinese and Western medicine treatment of infertility with polycystic ovary syndrome. China Journal of Chinese Medicine 2014;29(7):1032-3.

Zhou Z 2014 {published data only}

1. 1. Zhou Z, Dang YM. [Wenjing decoction observation deficiency polycystic ovary syndrome patients]. Traditional Chinese Medicine Journal 2014;(2):56-8.

Zhu 2009 {published data only}

1. 1. Zhu Y, Wang XG. Clinical observation on polycystic ovary syndrome treated with integrated medicine. Zhejiang Journal of Integrated Traditional Chinese and Western Medicine 2009;19(11):665-7.

Zhu 2014 {published data only}

1. 1. Zhu XN, Zong LL, Hao S, Guan YC. [Integrative medicine 32 cases of infertility polycystic ovary syndrome]. Henan Traditional Chinese Medicine 2014;34(7):1355-6.

Zhu 2019 {published data only}

1. 1. Zhu YS. Clinical observation on the treatment of dysovulation infertility of polycystic ovary syndrome with Jiajianwenjing Decoction. Guangming Journal of Chinese Medicine 2019;34(5):742-4.

Zhu 2020 {published data only}

1. 1. Zhu LN, Zhang ZH, Liu LN. Zuogui Shugan Decoction Combined with Clomiphene in Treating 46 Cases of Polycystic Ovary Syndrome Infertility. Forum On Traditional Chinese Medicine 2020;35(2):42-4.

Zhuang 2008 {published data only}

1. 1. Zhuang XY, Chen MF. Clinical research on Chinese herbal medicine combined with clomiphene in treating PCOS. Journal of New Chinese Medicine 2008;40(9):61-2.

Zhu JQ 2012 {published data only}

1. 1. Zhu JQ. Clinical study on the effect of polycystic ovary syndrome with insulin resistance by the method of invigorating the kidney and regulating menstruation cycles [Masters thesis]. Nanjing (China): Nanjing University of Traditional Chinese Medicine, 2012.

Zhu M 2012 {published data only}

1. 1. Zhu M. Clinical research on combination Ling-zhu granule and acupoint catgut embedding in treating polycystic ovary syndrome with insulin resistance [Masters thesis]. Guangzhou (China): Guangzhou University of Chinese Medicine, 2012.

Zhu TC 2013 {published data only}

1. 1. Zhu TC. Integrative medicine 18 cases of polycystic ovary syndrome. Guangming Journal of Chinese Medicine 2013;28(7):1427-8.

Zhu Y 2013 {published data only}

1. 1. Zhu Y, Wang XG. Infertility treatment in polycystic ovary syndrome with traditional Chinese medicine combined with Western medicine. Zhejiang Journal of Integrated Traditional Chinese and Western Medicine 2013;23(11):872-5, 85.

Zou 2012 {published data only}

1. 1. Zou XQ. The curative effect of nursing intervention combined with traditional Chinese and Western medicine treatment for polycystic ovary syndrome. Health Must Read Magazine 2012;(4):54.

Zou L 2014 {published data only}

1. 1. Zou L, Tan AH. Polycystic ovary syndrome in combination therapy effectiveness analysis. Journal of Medical Information 2014;(21):611-2.

Zou Y 2014 {published data only}

1. 1. Zou Y. Integrative medicine 33 cases of polycystic ovary syndrome. Journal of Community Medicine 2014;12(3):34-5.

Zuo 2011 {published data only}

1. 1. Zuo J. The clinical study on the "jiajian fang fen tong shen san" effect of overweight type of polycystic ovarian syndrome [Masters thesis]. Nanjing (China): Nanjing University of Chinese Medicine, 2011.

References to ongoing studies

Xu 2020 {published data only}

1. 1. Xu W, Tang M, Wang J, Wang L. Clinical effects of Shou-Wu Jiang-Qi Decoction combined acupuncture on the treatment of Polycystic Ovarian Syndrome with kidney deficiency, phlegm and blood stasisness: Study protocol clinical trial (SPIRIT Compliant). Medicine 2020;99(12):e19045. - PMC - PubMed

Additional references

Ali 2015

1. 1. Ali A T. Polycystic ovary syndrome and metabolic syndrome. Ceska Gynekol 2015;80(4):279-89. - PubMed

Alvarez‐Blasco 2006

1. 1. Alvarez-Blasco F, Botella-Carretero JI, San Millán JL, Escobar-Morreale HF. Prevalence and characteristics of the polycystic ovary syndrome in overweight and obese women. Archives of Internal Medicine 2006;166(19):2081-6. - PubMed

ASRM 2017

1. 1. Practice Committee of the American Society for Reproductive Medicine. Role of metformin for ovulation induction in infertile patients with polycystic ovary syndrome (PCOS): a guideline. Fertil Steril 2017;108(3):426-41. - PubMed

Bani 2017

1. 1. Bani MM, Majdi SA. Polycystic Ovary Syndrome (PCOS), Diagnostic Criteria, and AMH. Asian Pac J Cancer Prev 2017;18(1):17-21. - PMC - PubMed

Berneis 2007

1. 1. Berneis K, Rizzo M, Lazzaroni V, Fruzzetti F, Carmina E. Atherogenic lipoprotein phenotype and low-density lipoproteins size and subclasses in women with polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 2007;92(1):186-9. - PubMed

Boomsma 2006

1. 1. Boomsma CM, Eijkemans MJ, Hughes EG, Visser GH, Fauser BC, Macklon NS. A meta-analysis of pregnancy outcomes in women with polycystic ovary syndrome. Human Reproduction Update 2006;12(6):673-83. - PubMed

Bordewijk 2020

1. 1. Bordewijk EM, Ng KYB, Rakic L, Mol BWJ, Brown J, Crawford TJ et al. Laparoscopic ovarian drilling for ovulation induction in women with anovulatory polycystic ovary syndrome. Cochrane Database of Systematic Reviews 2020, Issue 2. Art. No: CD001122. [DOI: 10.1002/14651858.CD001122.pub5] - DOI - PMC - PubMed

Bozdag 2016

1. 1. Bozdag G, Mumusoglu S, Zengin D, Karabulut E, Yildiz B O. The prevalence and phenotypic features of polycystic ovary syndrome: a systematic review and meta-analysis. Hum Reprod 2016;31(12):2841-55. - PubMed

Carmina 1999

1. 1. Carmina E, Lobo RA. Polycystic ovary syndrome (PCOS): arguably the most common endocrinopathies associated with significant morbidity in women. Journal of Clinical Endocrinology and Metabolism 1999;84(6):1897-9. - PubMed

Chen 2018

1. 1. Chen H, Wang C, Lin T. WANG CuixiaTonifying the Kidney and Benefiting the Essence-Activate Blood Circulation and Remove Blood Stasis DialecticalTreatment by Stages of Polycystic Ovary Syndrome (Kidney Deficiency and Blood Stasis). Journal of Practical Traditional Chinese Internal Medicine 2018;32(8):15-7.

Cong 2006

1. 1. Cong LX. [Observation of Tiaojin Zhuyun Pellet combined with clomiphene in treating infertility caused by PCOS]. Journal of Practical Traditional Chinese Medicine 2006;22(5):290-1.

Costello 2007

1. 1. Costello M, Shrestha B, Eden J, Sjoblom P, Johnson N. Insulin-sensitising drugs versus the combined oral contraceptive pill for hirsutism, acne and risk of diabetes, cardiovascular disease, and endometrial cancer in polycystic ovary syndrome. Cochrane Database of Systematic Reviews 2007, Issue 1. Art. No: CD005552. [DOI: 10.1002/14651858.CD005552.pub2] - DOI - PubMed

Cui 2004

1. 1. Cui FY, Liu XM. Gaoshao soup in treating 60 cases of PCOS. Journal of Practical Traditional Chinese Medicine 2004;20(12):686-7.

Dunaif 1997

1. 1. Dunaif A. Insulin resistance and the polycystic ovary syndrome mechanism and implications for pathogenesis. Endocrine Reviews 1997;18(6):774-800. - PubMed

Egger 1997

1. 1. Egger M, Smith GD, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997;315(7109):629-34. - PMC - PubMed

Ehrmann 1999

1. 1. Ehrmann DA, Barnes RB, Rosenfield RL, Cavaghan MK, Imperial J. Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care 1999;22(1):141-6. - PubMed

Escobar‐Morreale 2005

1. 1. Escobar-Morreale HF, Luque-Ramírez M, San Millán JL. The molecular genetic basis of functional hyperandrogenism and polycystic ovary syndrome. Endocrine Reviews 2005;26(2):251-82. - PubMed

ESHRE/ASRM 2004

1. 1. The Rotterdam ESHRE/ASRM Sponsored PCOS consensus workshop group. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Human Reproduction 2004;19(1):41-7. - PubMed

Filippou 2017

1. 1. Filippou P, Homburg R. Is foetal hyperexposure to androgens a cause of PCOS? Hum Reprod Update 2017;23(4):421-32. - PubMed

Gambineri 2006

1. 1. Gambineri A, Pasquali R. Insulin resistance, obesity and metabolic syndrome in polycystic ovary syndrome. Endocrinología y Nutrición 2006;53(S1):49-55.

GRADEpro GDT [Computer program]

1. 1. GRADEpro GDT. Version accessed 15 August 2019. Hamilton (ON): McMaster University (developed by Evidence Prime). Available at gradepro.org.

He 2020

1. 1. He S, Ning Y, Jiang SY, Liu DY, Wu FT, Hou HR. Network Pharmacology Research of Huanglian in Treatment of Polycystic Ovary Syndrome with Hyperandrogenism. Journal of Nanjing University of Traditional Chinese Medicine 2020;36(4):498-503.

Higgins 2002

1. 1. Higgins JP, Thompson SG. Quantifying heterogeneity in a metaanalysis. Statistics in Medicine 2002;21(11):1539-58. - PubMed

Higgins 2011

1. 1. Higgins JP, Green S editor(s). Cochrane Handbook for Systematic Reviews of Interventions. Version 5.1.0 [updated March 2011]. The Cochrane Collaboration, 2011. Available from training.cochrane.org/handbook/archive/v5.1/.

Hou 2012

1. 1. Hou F, Shi YQ. The progress on etiology of polycystic ovary syndrome in traditional Chinese medicine. Journal of Changchun University of Traditional Chinese Medicine 2012;28(5):932-34.

Huang C 2019

1. 1. Huang C, Zhao W. [Experience of professor ZHAO Wei on treatment of the infertility caused by PCOS]. Journal of Zhejiang Chinese Medical University 2019;43(4):346-9.

ICHEWG 1997

1. 1. International Conference on Harmonisation Expert Working Group. International conference on harmonisation of technical requirements for registration of pharmaceuticals for human use. ICH harmonised tripartite guideline. Guideline for good clinical practice. CFR & ICH Guidelines. 1st edition. Needham, Massachusetts, USA: Barnett International/PAREXEL, 1997.

Jadad 1996

1. 1. Jadad AR, Moore RA, Carroll D, Jenkinson C, Reynolds DJ, Gavaghan DJ, et al. Assessing the quality of reports of randomized clinical trials: is blinding necessary? Controlled Clinical Trials 1996;17(1):1-12. - PubMed

Jin 1986

1. 1. Jin WX, Sun SX, Wang CY. Research on Luole in treating female ovulatory disorder. Journal of Fujian College of Traditional Chinese Medicine 1986;10(2):11-3.

Jin 2018

1. 1. Jin CB. Advances in the treatment of insulin resistance molecular mechanisms in Traditional Chinese medicine and active ingredients. Diet Health 2018;5(4):295-6.

Jüni 2001

1. 1. Jüni P, Altman DG, Egger M. Systematic reviews in health care: Assessing the quality of controlled clinical trials. BMJ 2001;323(7303):42-6. - PMC - PubMed

Kim 2013

1. 1. Kim J H, Kwong E M, Chung V C, Lee J C, Wong T, Goggins W B. Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese. BMC Complement Altern Med 2013;13:336. - PMC - PubMed

Kjaergard 2001

1. 1. Kjaergard LL, Villumsen J, Gluud C. Reported methodological quality and discrepancies between large and small randomized trials in meta-analyses. Annals of Internal Medicine 2001;135(11):982-9. - PubMed

Lampert 2002

1. 1. Lampert N, Xu Y. Chinese herbal nephropathy. The Lancet 2002;359(9308):796-7. - PubMed

Lee 2021

1. 1. Lee J W, Hyun M K, Kim H J, Kim D I. Acupuncture and herbal medicine for female infertility: an overview of systematic reviews. Integr Med Res 2021;10(3):100694. - PMC - PubMed

Legro 1999

1. 1. Legro RS, Kunselman AR, Dodson WC, Dunaif A. Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome a prospective, controlled study in 254 affected women. Journal of Clinical Endocrinology and Metabolism 1999;84(1):165-9. - PubMed

Legro 2001

1. 1. Legro RS, Kunselman AR, Dunaif A. Prevalence and predictors of dyslipidemia in women with polycystic ovary syndrome. American Journal of Medicine 2001;111(8):607-13. - PubMed

Li 2006

1. 1. Li CP. [Effective observation on Bushen Tiaozhou Method in treating 30 infertility patients with PCOS]. New Journal of Traditional Chinese Medicine 2006;38(1):50-1.

Lim 2019

1. 1. Lim S S, Hutchison S K, Van Ryswyk E, Norman R J, Teede H J, Moran L J. Lifestyle changes in women with polycystic ovary syndrome. Cochrane Database Syst Rev 2019;3(3):Cd007506. - PMC - PubMed

Liu 2005

1. 1. Liu Y, Lu XY. Traditional Chinese medicine in treating 12 PCOS. New Journal of Traditional Chinese Medicine 2005;37(8):74-5.

Lo 2006a

1. 1. Lo JC, Feigenbaum SL, Escobar GJ, Yang J, Crites YM, Ferrara A. Increased prevalence of gestational diabetes mellitus among women with diagnosed polycystic ovary syndrome a population based study. Diabetes Care 2006;29(8):1915-7. - PubMed

Lo 2006b

1. 1. Lo JC, Feigenbaum SL, Yang J, Pressman AR, Selby JV, Go AS. Epidemiology and adverse cardiovascular risk profile of diagnosed polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 2006;91(4):1357-63. - PubMed

Lord 2001

1. 1. Lord GM, Cook T, Arlt VM, Schmeiser HH, Williams G, Pusey CD. Urothelial malignant disease and Chinese herbal nephropathy. The Lancet 2001;358(9292):1515-6. - PubMed

Moher 1998

1. 1. Moher D, PhamB, Jones A, Cook DJ, Jadad A, Moher M, et al. Does quality of reports of randomised trials affect estimates of intervention efficacy reported in meta-analysis. The Lancet 1998;352(9128):609-13. - PubMed

Moini 2019

1. 1. Moini Jazani A, Nasimi Doost Azgomi H, Nasimi Doost Azgomi A, Nasimi Doost Azgomi R. A comprehensive review of clinical studies with herbal medicine on polycystic ovary syndrome (PCOS). Daru: Journal of Faculty of Pharmacy, Tehran University of Medical Sciences 2019;27(2):863-77. - PMC - PubMed

Ni 2007

1. 1. Ni HY, Gong J. Research progress on Chinese herbal medicine in treating PCOS. Liaoning Journal of Traditional Chinese Medicine 2007;34(1):123-4.

Ning 2004

1. 1. Ning MH, Liu YJ, Ning XG. Clinical observation on Yishenxiaozheng decoction for the treatment of 85 cases of polycystic ovarian disease. Hunan Guiding Journal of Traditional Chinese Medicine 2004;10(3):27-8.

Nortier 2000

1. 1. Nortier JL, Martinez MC, Schmeiser HH, Arlt VM, Bieler CA, Petein M, et al. Urothelial carcinoma associated with the use of a Chinese herb (Aristolochia fangchi). The New England Journal of Medicine 2000;342(23):1686-92. - PubMed

Ozcan 2017

1. 1. Ozcan Dag Z, Alpua M, Isik Y, Buturak S V, Tulmac O B, Turkel Y. The evaluation of temperament and quality of life in patients with polycystic ovary syndrome. Gynecol Endocrinol 2017;33(3):250-3. - PubMed

Peng 2019

1. 1. Peng XJ, Xu HY, Chen YB, Yang CH, Xu G, Liu YH, et al. Analysis of Danggui Liuhuang Decoction for Treatment of Diabetes Based on Network Pharmacology. Traditional Chinese Drug Research and Clinical Pharmacology 2019;30(8):952-8.

Rajkhowa 1997

1. 1. Rajkhowa M, Neary RH, Kumpatla P, Garne FL, Jones PW, Obhrai MS, et al. Altered composition of high density lipoproteins in women with the polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 1997;82(10):3389-94. - PubMed

Rao 2019

1. 1. Rao L, Zhu H. Progress in the treatment of infertility caused by polycystic ovary syndrome with traditional Chinese and Western Medicine. Hubei Journal of Traditional Chinese Medicine 2019;41(7):60-2.

RevMan 2014 [Computer program]

1. 1. Review Manager (RevMan). Version 5.3. Copenhagen: The Nordic Cochrane Centre, The Cochrane Collaboration, 2014.

Ried 2015

1. 1. Ried K. Chinese herbal medicine for female infertility: an updated meta-analysis. Complement Ther Med 2015;23(1):116-28. - PubMed

Schulz 1995

1. 1. Schulz KF, Chalmers I, Hayes RJ, Altman DG. Empirical evidence of bias. Dimensions of methodological quality associated with estimates of treatment effects in controlled trials. JAMA 1995;273(5):408-12. - PubMed

Sinawat 2012

1. 1. Sinawat S, Buppasiri P, Lumbiganon P, Pattanittum P. Long versus short course treatment with metformin and clomiphene citrate for ovulation induction in women with PCOS. Cochrane Database of Systematic Reviews 2012, Issue 10. Art. No: CD006226. [DOI: 10.1002/14651858.CD006226.pub3] - DOI - PubMed

Sun 1981

1. 1. Sun YL, Guo HR, Yu J, Li CJ. [133 cases of polycystic ovarian syndrome treated by the method 'nourishing kidney and sputum-reducing']. Shanghai Journal of Traditional Chinese Medicine 1981;15(06):14.

Talbott 1998

1. 1. Talbott I, Clerici A, Berga SL, Kuller L, Guzick D, Detre K, et al. Adverse lipid and coronary heart disease risk profiles in young women with polycystic ovary syndrome results of a case control study. Journal of Clinical Epidemiology 1998;51(5):415-22. - PubMed

Tan 2012

1. 1. Tan L, Tong Y, Sze S C, Xu M, Shi Y, Song X Y, et al. Chinese herbal medicine for infertility with anovulation: a systematic review. J Altern Complement Med 2012;18(12):1087-100. - PubMed

Tang 2012a

1. 1. Tang T, Lord JM, Norman RJ, Yasmin E, Balen AH. Insulin-sensitising drugs (metformin, rosiglitazone, pioglitazone, D-chiro-inositol) for women with polycystic ovary syndrome, oligo amenorrhoea and subfertility. Cochrane Database of Systematic Reviews 2012, Issue 5. Art. No: CD003053. [DOI: 10.1002/14651858.CD003053.pub5] - DOI - PubMed

Wang 1982

1. 1. Wang ZQ, Shi LY, Wang DZ. The effect of "Long Dan Xie Gan Tang" treat polycystic ovary syndrome. Shanghai Journal of Traditional Chinese Medicine 1982;(12):16-7.

Wang 2005

1. 1. Wang ZH, Yang YS, Zhang YL. Clinical study of Ganshao capsule in treating clomiphene-resistant polycystic ovarian syndrome. Zhongguo Zhong Xi Yi Jie He Za Zhi [Chinese Journal of Integrated Traditional and Western Medicine] 2005;25(8):704-6. - PubMed

Wang 2008

1. 1. Wang BQ, Ling M. Research development of Chinese herbal medicine for PCOS. Shandong Journal of Traditional Chinese Medicine 2008;27(2):138-40.

Weiss 2015

1. 1. Weiss NS, Nahuis M, Bayram N, Mol BWJ, Van der Veen F, Wely M. Gonadotrophins for ovulation induction in women with polycystic ovarian syndrome. Cochrane Database of Systematic Reviews 2015, Issue 9. Art. No: CD010290. [DOI: 10.1002/14651858.CD010290.pub2] - DOI - PubMed

Xu L 2017

1. 1. Xu L, Qiao X. Acupuncture is not as effective as infertility treatment in women with PCOS. Evid Based Med 2017;22(6):229-30. - PMC - PubMed

Yang 2006

1. 1. Yang ZW, You ZL, Zhang XH, Wang Y, Zeng M. Research on influence of Bushen Huoxue Method on menstrual cyclicity and reproductive hormone in PCOS. Chinese Journal of Traditional Medical Science and Technology 2006;13(1):5-6.

Yildiz 2012

1. 1. Yildiz BO, Bozdag G, Yapici Z, Esinler I, Yarali H. Prevalence, phenotype and cardiometabolic risk of polycystic ovary syndrome under different diagnostic criteria. Hum Reprod 2012;27(10):3067-73. - PubMed

Yuan 2003

1. 1. Yuan XF. Traditional Chinese Mdeicine periodical treatment on 38 PCOS. Fujian Journal of Traditional Chinese Medicine 2003;34(2):22.

Yv 1981

1. 1. Yv XL, Li YA. 99 cases of Chinese and Western treatment of polycystic ovary syndrome. Shanghai Medical Journal 1981;4(1):50.

Zhang 2004

1. 1. Zhang QP. Bushen Huoxue Method in treating PCOS. Chinese Journal of Information on Traditional Chinese Medicine 2004;11(11):1014-5.

References to other published versions of this review

Zhang 2009

1. 1. Zhang J, Zhou L, Tang L, Wu T, Lim CED. Chinese herbal medicine for subfertile women with polycystic ovarian syndrome. Cochrane Database of Systematic Reviews 2009, Issue 1. Art. No: CD007535. [DOI: 10.1002/14651858.CD007535] - DOI - PubMed

Zhang 2010

1. 1. Zhang J, Li T, Zhou L, Tang L, Xu L, Wu T, et al. Chinese herbal medicine for subfertile women with polycystic ovarian syndrome. Cochrane Database of Systematic Reviews 2010, Issue 9. Art. No: CD007535. [DOI: 10.1002/14651858.CD007535.pub2] - DOI - PubMed

Zhou 2016

1. 1. Zhou K, Zhang J, Xu L, Wu T, Lim CED. Chinese herbal medicine for subfertile women with polycystic ovarian syndrome. Cochrane Database Syst Rev 2016;10:Cd007535. - PMC - PubMed