Cluster of Angiostrongyliasis Cases Following Consumption of Raw Monitor Lizard in the Lao People's Democratic Republic and Review of the Literature - PubMed (original) (raw)
Case Reports
Cluster of Angiostrongyliasis Cases Following Consumption of Raw Monitor Lizard in the Lao People's Democratic Republic and Review of the Literature
Leeyounjera Yang et al. Trop Med Infect Dis. 2021.
Abstract
Angiostrongyliasis in humans causes a range of symptoms from mild headache and myalgia to neurological complications, coma and death. Infection is caused by the consumption of raw or undercooked intermediate or paratenic hosts infected with Angiostrongylus cantonensis or via contaminated vegetables or water. We describe a cluster of cases involved in the shared meal of wild raw monitor lizard in the Lao PDR. Seven males, aged 22-36 years, reported headaches, abdominal pain, arthralgia, myalgia, nausea/vomiting, diarrhea, neurological effects and loss of appetite. Five were admitted to hospital. The final diagnosis was made by clinical presentation and case history, and positive A. cantonensis PCR for two cases. All hospitalized patients recovered fully following supportive treatment. The remaining two individuals sought local home remedies and made full recovery. Whilst most published reports concern infections via consumption of molluscs, few detailed reports exist on infections that result from the consumption of reptiles and there exists little awareness in Lao PDR. This case cluster, which originates from a single meal, highlights the potential public health risk of the consumption of raw and wild-caught meat in Lao PDR and the Southeast Asia region. Without specific diagnostics, clinical history and the consideration of recent food consumption are important when evaluating patients.
Keywords: Angiostrongylus cantonensis; Laos; angiostrongyliasis; eosinophilic meningitis; zoonosis.
Conflict of interest statement
The authors declare no conflict of interest.
Figures
Figure 1
Live monitor lizard sold at a local wet market in the Lao PDR.
Figure 2
Timeline for cases 1 to 5. HCC = Healthcare clinic; DH = District Hospital; PH = Provincial Hospital.
Similar articles
- An Overview of Angiostrongylus cantonensis (Nematoda: Angiostrongylidae), an Emerging Cause of Human Angiostrongylosis on the Indian Subcontinent.
Pandian D, Najer T, Modrý D. Pandian D, et al. Pathogens. 2023 Jun 20;12(6):851. doi: 10.3390/pathogens12060851. Pathogens. 2023. PMID: 37375541 Free PMC article. Review. - Angiostrongylus cantonensis: a review of its distribution, molecular biology and clinical significance as a human pathogen.
Barratt J, Chan D, Sandaradura I, Malik R, Spielman D, Lee R, Marriott D, Harkness J, Ellis J, Stark D. Barratt J, et al. Parasitology. 2016 Aug;143(9):1087-118. doi: 10.1017/S0031182016000652. Epub 2016 May 26. Parasitology. 2016. PMID: 27225800 Review. - Unusual Larva in the CSF and Unique MRI Findings in a Case of Eosinophilic Meningitis.
Rai S, Madi D, Pai S, Baliga S. Rai S, et al. J Clin Imaging Sci. 2014 Dec 31;4:76. doi: 10.4103/2156-7514.148303. eCollection 2014. J Clin Imaging Sci. 2014. PMID: 25806134 Free PMC article. - Three cases of intestinal capillariasis in Lao People's Democratic Republic.
Soukhathammavong P, Sayasone S, Harimanana AN, Akkhavong A, Thammasack S, Phoumindr N, Choumlivong K, Choumlivong K, Keoluangkhot V, Phongmany S, Akkhavong K, Hatz C, Strobel M, Odermatt P. Soukhathammavong P, et al. Am J Trop Med Hyg. 2008 Nov;79(5):735-8. Am J Trop Med Hyg. 2008. PMID: 18981514
Cited by
- Angiostrongyliasis: A Changing Scenario?
Bruschi F. Bruschi F. Pathogens. 2023 Oct 3;12(10):1214. doi: 10.3390/pathogens12101214. Pathogens. 2023. PMID: 37887730 Free PMC article. - An Overview of Angiostrongylus cantonensis (Nematoda: Angiostrongylidae), an Emerging Cause of Human Angiostrongylosis on the Indian Subcontinent.
Pandian D, Najer T, Modrý D. Pandian D, et al. Pathogens. 2023 Jun 20;12(6):851. doi: 10.3390/pathogens12060851. Pathogens. 2023. PMID: 37375541 Free PMC article. Review. - Neuroangiostrongyliasis: Global Spread of an Emerging Tropical Disease.
Cowie RH, Ansdell V, Panosian Dunavan C, Rollins RL. Cowie RH, et al. Am J Trop Med Hyg. 2022 Nov 7;107(6):1166-1172. doi: 10.4269/ajtmh.22-0360. Print 2022 Dec 14. Am J Trop Med Hyg. 2022. PMID: 36343594 Free PMC article. - Paratenic hosts of Angiostrongylus cantonensis and their relation to human neuroangiostrongyliasis globally.
Turck HC, Fox MT, Cowie RH. Turck HC, et al. One Health. 2022 Aug 6;15:100426. doi: 10.1016/j.onehlt.2022.100426. eCollection 2022 Dec. One Health. 2022. PMID: 36277113 Free PMC article. Review. - Sociocultural Factors Influencing Human Streptococcus suis Disease in Southeast Asia.
Kerdsin A, Segura M, Fittipaldi N, Gottschalk M. Kerdsin A, et al. Foods. 2022 Apr 20;11(9):1190. doi: 10.3390/foods11091190. Foods. 2022. PMID: 35563913 Free PMC article. Review.
References
- Jarvi S.I., Quarta S., Jacquier S., Howe K., Bicakci D., DaSalla C., Lovesy N., Snook K., McHugh R., Niebuhr C.N. High prevalence of Angiostrongylus cantonensis (rat lungworm) on eastern Hawai’i Island: A closer look at life cycle traits and patterns of infection in wild rats (Rattus spp.) PLoS ONE. 2017;12:e0189458. doi: 10.1371/journal.pone.0189458. - DOI - PMC - PubMed
Publication types
LinkOut - more resources
Full Text Sources