Sleep state misperception: is there a CNS structural source? - PubMed (original) (raw)

Case Reports

Sleep state misperception: is there a CNS structural source?

Giselle de Martin Truzzi et al. Sleep Sci. 2021 Jan-Mar.

Abstract

Introduction: We describe a case of sleep state misperception in a patient with a neurotoxoplasmosis lesion in the left nucleocapsular region.

Case report: A 40-year-old female patient presented relating sleeplessness over the past 2 years, concurrent with progressive headaches, dizziness and motor and sensory deficits in the right upper and lower limbs. She had a history of AIDS, on irregular antiretroviral therapy and neurotoxoplasmosis. A polysomnography confirmed the hypothesis of sleep state misperception, and magnetic resonance imaging revealed a residual lesion in the left nucleocapsular region.

Conclusion: Different models consider that the sleep state misperception could be correlated to structural abnormalities of the central nervous system. A recent study showed that the medial prefrontal cortex had a lower activation in patients with unrefreshing sleep due to chronic fatigue syndrome. This case report highlights the possibility of sleep state misperception having - at least partially - an anatomical substrate in the left nucleocapsular region.

Keywords: Acquired Immunodeficiency Syndrome; Sleep; Sleep Initiation and Maintenance Disorders; Toxoplasmosis, Cerebral.

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Figures

Figure 1

MRI of the brain shows a residual lesion in the left nucleocapsular region (red arrow).

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References

1. 1. van der Walt JP, Johannsen E. The dangeardien and its significance in the taxonomy of the ascomycetous yeasts. J Urol. 1974 May;111(5):630–636. - PubMed
2. 1. Ito E, Inoue Y. International Classification of Sleep Disorders - third edition (ICSD-3). American Academy of Sleep Medicine. Nihon Rinsho. 2015 Jun;73(6):916–923. - PubMed
3. 1. Choi SJ, Suh S, Ong J, Joo E Y. Sleep misperception in chronic insomnia patients with obstructive sleep apnea syndrome: implications for clinical assessment. J Clin Sleep Med. 2016 Nov;12(11):1517–1525. - PMC - PubMed
4. 1. Harvey AG, Tang NK. (Mis)perception of sleep in insomnia: a puzzle and a resolution. Psychol Bull. 2012;138(1):77–101. - PMC - PubMed
5. 1. Bianchi MT, Williams KL, McKinney S, Ellenbogen JM. The subjective-objective mismatch in sleep perception among those with insomnia and sleep apnea. J Sleep Res. 2013 Oct;22(5):557–568. - PubMed

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