Acute otitis media caused by Branhamella catarrhalis: biology and therapy - PubMed (original) (raw)
Clinical Trial
. 1987 Jan-Feb;9(1):16-27.
doi: 10.1093/clinids/9.1.16.
- PMID: 3493519
- DOI: 10.1093/clinids/9.1.16
Clinical Trial
Acute otitis media caused by Branhamella catarrhalis: biology and therapy
G F Van Hare et al. Rev Infect Dis. 1987 Jan-Feb.
Abstract
Since 1980, we have observed an epidemic of otitis media caused by Branhamella catarrhalis. This event was characterized by studying the nasopharyngeal colonization of infants and children with B. catarrhalis and the clinical presentation and therapeutic outcome of acute otitis media caused by this organism. Pharyngeal colonization with B. catarrhalis was commoner in winter than summer. B. catarrhalis was present in middle-ear fluid (MEF) of 17% of children with otitis media, and was commoner in fall and winter (20%) than in spring and summer (11%, P less than .05). Seventy-five percent of isolates produced beta-lactamase (Ravasio type). In five of 20 patients, treatment with beta-lactamase-susceptible agents failed to sterilize B. catarrhalis-infected MEF. All of these five patients were infected with beta-lactamase-producing strains. The increasing prominence of antibiotic-resistant B. catarrhalis in acute otitis media may lead to a reevaluation of initial antibiotic therapy for acute otitis media, particularly in winter or in areas where colonization with such strains is prevalent.
Similar articles
- Therapy of acute otitis media caused by Branhamella catarrhalis. Preliminary report.
Shurin PA, Van Hare GF. Shurin PA, et al. Drugs. 1986;31 Suppl 3:122-4. doi: 10.2165/00003495-198600313-00027. Drugs. 1986. PMID: 3488191 - Acute otitis media in Sweden. Role of Branhamella catarrhalis and the rationale for choice of antimicrobial therapy.
Lundgren K, Ingvarsson L. Lundgren K, et al. Drugs. 1986;31 Suppl 3:125-31. doi: 10.2165/00003495-198600313-00028. Drugs. 1986. PMID: 3488192 - [Nasopharyngeal and middle ear flora in children with acute otitis media].
Zielnik-Jurkiewicz B, Kolczyńska M. Zielnik-Jurkiewicz B, et al. Otolaryngol Pol. 2005;59(4):537-42. Otolaryngol Pol. 2005. PMID: 16273858 Polish. - Pharmacotherapy of otitis media.
Thoene DE, Johnson CE. Thoene DE, et al. Pharmacotherapy. 1991;11(3):212-21. Pharmacotherapy. 1991. PMID: 1862012 Review. - [Clinical, diagnostic and therapeutic aspects of Moraxella catarrhalis infections].
Bourgeois F, Lambert-Zechovsky N, Bingen E. Bourgeois F, et al. Pathol Biol (Paris). 1993 Jun;41(6):555-61. Pathol Biol (Paris). 1993. PMID: 8247636 Review. French.
Cited by
- Profiling bacterial community in upper respiratory tracts.
Yi H, Yong D, Lee K, Cho YJ, Chun J. Yi H, et al. BMC Infect Dis. 2014 Nov 13;14:583. doi: 10.1186/s12879-014-0583-3. BMC Infect Dis. 2014. PMID: 25391813 Free PMC article. - Molecular epidemiological characterization of respiratory isolates of Moraxella catarrhalis in a pediatric intensive care unit.
Matlow AG, Low DE, Paret G, Jarrett S, Bohn D, Barker G, Boulanger J, Ford-Jones EL. Matlow AG, et al. Can J Infect Dis. 1992 Jul;3(4):189-92. doi: 10.1155/1992/370326. Can J Infect Dis. 1992. PMID: 22514369 Free PMC article. - Impact of bacterial colonization on the severity, and accompanying airway inflammation, of virus-induced wheezing in children.
Yu D, Wei L, Zhengxiu L, Jian L, Lijia W, Wei L, Xiqiang Y, Xiaodong Z, Zhou F, Enmei L. Yu D, et al. Clin Microbiol Infect. 2010 Sep;16(9):1399-404. doi: 10.1111/j.1469-0691.2009.03147.x. Clin Microbiol Infect. 2010. PMID: 20041894 Free PMC article. - Characteristics of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus isolated from the nasopharynx of healthy children attending day-care centres in the Czech Republic.
Zemlicková H, Urbásková P, Adámková V, Motlová J, Lebedová V, Procházka B. Zemlicková H, et al. Epidemiol Infect. 2006 Dec;134(6):1179-87. doi: 10.1017/S0950268806006157. Epub 2006 May 10. Epidemiol Infect. 2006. PMID: 16684402 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources
Medical