Portal Vein Thrombosis and Pyogenic Liver Abscess With Concomitant Bacteroides Bacteremia in a Patient With COVID-19 Infection: A Case Report and Brief Review - PubMed (original) (raw)

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Portal Vein Thrombosis and Pyogenic Liver Abscess With Concomitant Bacteroides Bacteremia in a Patient With COVID-19 Infection: A Case Report and Brief Review

George Trad et al. J Investig Med High Impact Case Rep. 2022 Jan-Dec.

Abstract

The 2019 coronavirus disease (COVID-19) can present with a wide variety of clinical manifestations, including a hypercoagulable state leading to both arterial and venous thrombosis. Portal vein thrombosis (PVT) in the setting of COVID-19 has rarely been reported in the medical literature. Pylephlebitis with concomitant liver abscess is a rare complication of intra-abdominal infection. Here, we present the case of a 49-year-old man who initially presented with intermittent fevers and generalized weakness of 1-month duration and was subsequently found to have COVID-19 infection, PVT, and Bacteroides fragilis bacteremia with associated pyogenic liver abscess. The patient was treated with intravenous antibiotics and oral anticoagulation with plan to follow up outpatient with gastroenterology in 3 months to ensure resolution of PVT and liver abscess.

Keywords: gastroenterology; hematology oncology; infectious disease; pulmonary critical care.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.

Figure 1.

Computed tomography of the abdomen and pelvis showing a 6.2 cm × 5.2 cm mass in the posterior segment of the right hepatic lobe with an associated 1.6 cm central abscess.

Figure 2.

Figure 2.

Computed tomography of the abdomen and pelvis demonstrated infiltrative lesion in the right lobe of the liver with thrombosis of the right portal vein.

Figure 3.

Figure 3.

Magnetic resonance imaging of the abdomen showing a 5 cm × 3.5 cm multiloculated hepatic abscess (a) and thrombosis of the posterior branch of the right portal vein (b).

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