Understudied proteins: opportunities and challenges for functional proteomics - PubMed (original) (raw)

Architecture of the outbred brown fat proteome defines regulators of metabolic physiology.

Xiao H, Bozi LHM, Sun Y, Riley CL, Philip VM, Chen M, Li J, Zhang T, Mills EL, Emont MP, Sun W, Reddy A, Garrity R, Long J, Becher T, Vitas LP, Laznik-Bogoslavski D, Ordonez M, Liu X, Chen X, Wang Y, Liu W, Tran N, Liu Y, Zhang Y, Cypess AM, White AP, He Y, Deng R, Schöder H, Paulo JA, Jedrychowski MP, Banks AS, Tseng YH, Cohen P, Tsai LT, Rosen ED, Klein S, Chondronikola M, McAllister FE, Van Bruggen N, Huttlin EL, Spiegelman BM, Churchill GA, Gygi SP, Chouchani ET. Xiao H, et al. Cell. 2022 Nov 23;185(24):4654-4673.e28. doi: 10.1016/j.cell.2022.10.003. Epub 2022 Nov 4. Cell. 2022. PMID: 36334589 Free PMC article.

Locus-specific proteome decoding reveals Fpt1 as a chromatin-associated negative regulator of RNA polymerase III assembly.

van Breugel ME, van Kruijsbergen I, Mittal C, Lieftink C, Brouwer I, van den Brand T, Kluin RJC, Hoekman L, Menezes RX, van Welsem T, Del Cortona A, Malik M, Beijersbergen RL, Lenstra TL, Verstrepen KJ, Pugh BF, van Leeuwen F. van Breugel ME, et al. Mol Cell. 2023 Dec 7;83(23):4205-4221.e9. doi: 10.1016/j.molcel.2023.10.037. Epub 2023 Nov 22. Mol Cell. 2023. PMID: 37995691 Free PMC article.