Peripheral blood eosinophil counts and bronchial responsiveness - PubMed (original) (raw)

Peripheral blood eosinophil counts and bronchial responsiveness

K J Taylor et al. Thorax. 1987 Jun.

Abstract

Bronchial responsiveness (histamine PC20) and peripheral blood eosinophil counts were measured in 23 asthmatic subjects, of whom 14 were atopic and nine non-atopic. In the group as a whole there was an inverse correlation between baseline eosinophil count and histamine PC20 (r = -0.71; p less than 0.001). For atopic subjects a relationship between eosinophil count and histamine PC20 was observed (r = -0.74; p less than 0.01), but there was no correlation between eosinophil count and baseline FEV1 or baseline FEV1 and histamine PC20. For the non-atopic subjects a similar relationship between eosinophil count and histamine PC20 was seen (r = -0.68; p less than 0.05) and a less significant inverse correlation between baseline eosinophil count and baseline FEV1 (r = -0.65; p less than 0.05). These results show a relationship between eosinophil count and non-specific bronchial responsiveness in both atopic and non-atopic asthma.

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References

    1. J Immunol. 1979 Dec;123(6):2925-7 - PubMed
    1. J Allergy Clin Immunol. 1984 Jul;74(1):41-8 - PubMed
    1. Acta Allergol. 1977 Oct;32(5):301-3 - PubMed
    1. Am Rev Respir Dis. 1978 Aug;118(2):287-94 - PubMed
    1. Clin Allergy. 1977 May;7(3):235-43 - PubMed

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