The association between low birth weight and caffeine consumption during pregnancy - PubMed (original) (raw)
The association between low birth weight and caffeine consumption during pregnancy
T R Martin et al. Am J Epidemiol. 1987 Nov.
Abstract
In a prospective study of 3,891 antenatal patients at Yale-New Haven Hospital between 1980 and 1982, 76.7% consumed caffeine from coffee, tea, colas, and drugs. A dose response of caffeine intake to increased risk for delivering low birth weight (less than 2,500 g) singleton newborns was observed. This relation was observed in deliveries after 36 weeks gestational age. When comparison was made with women who had no caffeine exposure, the relative risks of low birth weight after adjustment for confounding factors were 1.4 (95% confidence interval (CI) 0.7-3.0) for 1-150 mg of caffeine daily; 2.3 (95% CI 1.1-5.2) for 151-300 mg; and 4.6 (95% CI 2.0-10.5) for over 300 mg. Decreases in mean birth weight were 6, 31, and 105 g, respectively. Gestational age did not appear to be related to caffeine consumption in the crude or adjusted analysis. Maternal caffeine intake seems to exert an effect on birth weight through growth retardation in term newborns.
Similar articles
- Relation of caffeine intake during pregnancy to intrauterine growth retardation and preterm birth.
Fortier I, Marcoux S, Beaulac-Baillargeon L. Fortier I, et al. Am J Epidemiol. 1993 May 1;137(9):931-40. doi: 10.1093/oxfordjournals.aje.a116763. Am J Epidemiol. 1993. PMID: 8317450 - Association of maternal caffeine consumption with decrements in fetal growth.
Bracken MB, Triche EW, Belanger K, Hellenbrand K, Leaderer BP. Bracken MB, et al. Am J Epidemiol. 2003 Mar 1;157(5):456-66. doi: 10.1093/aje/kwf220. Am J Epidemiol. 2003. PMID: 12615610 - Caffeine consumption during pregnancy and fetal growth.
Fenster L, Eskenazi B, Windham GC, Swan SH. Fenster L, et al. Am J Public Health. 1991 Apr;81(4):458-61. doi: 10.2105/ajph.81.4.458. Am J Public Health. 1991. PMID: 2003624 Free PMC article. - Teratogen update: evaluation of the reproductive and developmental risks of caffeine.
Christian MS, Brent RL. Christian MS, et al. Teratology. 2001 Jul;64(1):51-78. doi: 10.1002/tera.1047. Teratology. 2001. PMID: 11410911 Review. - [Caffeine consumption during pregnancy and prevalence of low birth weight and prematurity: a systematic review].
Pacheco AH, Barreiros NS, Santos IS, Kac G. Pacheco AH, et al. Cad Saude Publica. 2007 Dec;23(12):2807-19. doi: 10.1590/s0102-311x2007001200002. Cad Saude Publica. 2007. PMID: 18157323 Review. Portuguese.
Cited by
- Exploring the caffeine-induced teratogenicity on neurodevelopment using early chick embryo.
Ma ZL, Qin Y, Wang G, Li XD, He RR, Chuai M, Kurihara H, Yang X. Ma ZL, et al. PLoS One. 2012;7(3):e34278. doi: 10.1371/journal.pone.0034278. Epub 2012 Mar 28. PLoS One. 2012. PMID: 22470550 Free PMC article. - Maternal caffeine consumption has irreversible effects on reproductive parameters and fertility in male offspring rats.
Dorostghoal M, Erfani Majd N, Nooraei P. Dorostghoal M, et al. Clin Exp Reprod Med. 2012 Dec;39(4):144-52. doi: 10.5653/cerm.2012.39.4.144. Epub 2012 Dec 31. Clin Exp Reprod Med. 2012. PMID: 23346524 Free PMC article. - Methodological challenges in the study of fetal growth.
Abell TD. Abell TD. Hum Nat. 1994 Mar;5(1):23-67. doi: 10.1007/BF02692191. Hum Nat. 1994. PMID: 24214463 - Low-birth-weight effects of demographic and socioeconomic variables and prenatal care in Pima County, Arizona.
Schwartz IL. Schwartz IL. West J Med. 1990 Jun;152(6):725-8. West J Med. 1990. PMID: 2353489 Free PMC article. - Cigarette, alcohol, and coffee consumption and prematurity.
McDonald AD, Armstrong BG, Sloan M. McDonald AD, et al. Am J Public Health. 1992 Jan;82(1):87-90. doi: 10.2105/ajph.82.1.87. Am J Public Health. 1992. PMID: 1536341 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical