Effects of Whey Protein Supplement on 4-Week Resistance Exercise-Induced Improvements in Muscle Mass and Isokinetic Muscular Function under Dietary Control - PubMed (original) (raw)
Randomized Controlled Trial
. 2023 Feb 16;15(4):1003.
doi: 10.3390/nu15041003.
Affiliations
- PMID: 36839361
- PMCID: PMC9963065
- DOI: 10.3390/nu15041003
Randomized Controlled Trial
Effects of Whey Protein Supplement on 4-Week Resistance Exercise-Induced Improvements in Muscle Mass and Isokinetic Muscular Function under Dietary Control
Chae-Been Kim et al. Nutrients. 2023.
Abstract
(1) The purpose of this study was to investigate the effect of whey protein supplementation under dietary control on improvements in muscle mass and function following resistance exercise training. (2) Thirty-two men were randomly assigned to a whey protein supplementation group taking whey protein isolate (PSG, n = 17) and a placebo group (CON, n = 15). Participants were provided with three meals per day corresponding to the estimated individual daily energy intake. The supervised resistance exercise program was conducted 60 min per day, six days per week, for four weeks. (3) Post-intervention, there was a significant interaction between groups in terms of muscle mass increase (p = 0.033, η2 = 0.14), with a greater increase in the PSG. There were also significant interactions between the groups and increases in peak torque of the dominant knee flexors (p = 0.048, η2 = 0.12), dominant shoulder extensors, and non-dominant shoulder extensors (p = 0.028, η2 = 0.15; p = 0.015, η2 = 0.18), and the total work of the dominant knee and shoulder extensors (p = 0.012, η2 = 0.19; p = 0.013, η2 = 0.19), with greater increases in the PSG. (4) These results suggest that whey protein supplementation enhances resistance exercise-induced increase in muscle mass and overall muscular strength and endurance, independent of dietary influence.
Keywords: dietary control; isokinetic muscular function; muscle mass; whey protein supplementation.
Conflict of interest statement
The authors declare no conflict of interest.
Figures
Figure 1
Changes in muscle mass after 4 weeks of resistance exercise. PSG, protein supplement group; CON, placebo group; * Significant difference pre versus post at p = 0.033; # significant interaction between the group and the change in muscle mass at p = 0.033.
Figure 2
(A) Changes in knee peak torque; (B) Changes in shoulder peak torque. PSG, protein supplement group; CON, placebo group; Ext, extensors; Flx, flexors; D, dominant; ND, non-dominant; Nm, Newton-meter. Assessments of peak torque consisted of 60°/s during joint flexion-extension. ** Significantly different within the group at p < 0.01; # significant interaction between the group and the change in peak torque at p < 0.05.
Figure 3
(A) Changes in knee joint total work; (B) Changes in shoulder joint total work. PSG, protein supplement group; CON, placebo group; Ext, extensors; Flx, flexors; D, dominant; ND, non-dominant joint; J, joule. Assessments of total work were performed at 180°/s during joint flexion-extension. * Significantly different within the group at p < 0.05, ** significantly different within the group at p < 0.01, *** significantly different within the group at p < 0.001; # significant interaction between groups and the change in total work at p < 0.05.
Figure 3
(A) Changes in knee joint total work; (B) Changes in shoulder joint total work. PSG, protein supplement group; CON, placebo group; Ext, extensors; Flx, flexors; D, dominant; ND, non-dominant joint; J, joule. Assessments of total work were performed at 180°/s during joint flexion-extension. * Significantly different within the group at p < 0.05, ** significantly different within the group at p < 0.01, *** significantly different within the group at p < 0.001; # significant interaction between groups and the change in total work at p < 0.05.
Similar articles
- Intake of whey isolate supplement and muscle mass gains in young healthy adults when combined with resistance training: a blinded randomized clinical trial (pilot study).
Duarte NM, Cruz AL, Silva DC, Cruz GM. Duarte NM, et al. J Sports Med Phys Fitness. 2020 Jan;60(1):75-84. doi: 10.23736/S0022-4707.19.09741-X. Epub 2019 Sep 23. J Sports Med Phys Fitness. 2020. PMID: 31565912 Clinical Trial. - The effects of whey protein with or without carbohydrates on resistance training adaptations.
Hulmi JJ, Laakso M, Mero AA, Häkkinen K, Ahtiainen JP, Peltonen H. Hulmi JJ, et al. J Int Soc Sports Nutr. 2015 Dec 16;12:48. doi: 10.1186/s12970-015-0109-4. eCollection 2015. J Int Soc Sports Nutr. 2015. PMID: 26677350 Free PMC article. Clinical Trial. - Effects of resistance exercise and whey protein supplementation on skeletal muscle strength, mass, physical function, and hormonal and inflammatory biomarkers in healthy active older men: a randomised, double-blind, placebo-controlled trial.
Griffen C, Duncan M, Hattersley J, Weickert MO, Dallaway A, Renshaw D. Griffen C, et al. Exp Gerontol. 2022 Feb;158:111651. doi: 10.1016/j.exger.2021.111651. Epub 2021 Dec 9. Exp Gerontol. 2022. PMID: 34896568 Clinical Trial. - Effects of Whey Protein Supplementation Pre- or Post-Resistance Training on Muscle Mass, Muscular Strength, and Functional Capacity in Pre-Conditioned Older Women: A Randomized Clinical Trial.
Nabuco HCG, Tomeleri CM, Sugihara Junior P, Fernandes RR, Cavalcante EF, Antunes M, Ribeiro AS, Teixeira DC, Silva AM, Sardinha LB, Cyrino ES. Nabuco HCG, et al. Nutrients. 2018 May 3;10(5):563. doi: 10.3390/nu10050563. Nutrients. 2018. PMID: 29751507 Free PMC article. Clinical Trial. - Effect of whey protein supplementation after resistance exercise on the muscle mass and physical function of healthy older women: A randomized controlled trial.
Mori H, Tokuda Y. Mori H, et al. Geriatr Gerontol Int. 2018 Sep;18(9):1398-1404. doi: 10.1111/ggi.13499. Epub 2018 Aug 16. Geriatr Gerontol Int. 2018. PMID: 30113122 Clinical Trial.
Cited by
- The Top 5 Can't-Miss Sport Supplements.
Antonio J, Pereira F, Curtis J, Rojas J, Evans C. Antonio J, et al. Nutrients. 2024 Sep 26;16(19):3247. doi: 10.3390/nu16193247. Nutrients. 2024. PMID: 39408214 Free PMC article. Review. - Combined Effects of Physical Activity and Diet on Cancer Patients: A Systematic Review and Meta-Analysis.
Dinas PC, On Behalf Of The Students Of Module Introduction To Systematic Reviews, Karaventza M, Liakou C, Georgakouli K, Bogdanos D, Metsios GS. Dinas PC, et al. Nutrients. 2024 Jun 2;16(11):1749. doi: 10.3390/nu16111749. Nutrients. 2024. PMID: 38892682 Free PMC article. Review. - Facilitators and barriers to the implementation of dietary nutrition interventions for community-dwelling older adults with physical frailty and sarcopenia: A qualitative meta-synthesis.
Chen L, Huang H, Jiang S, Yao H, Xu L, Huang Q, Xiao M, Zhao Q. Chen L, et al. Int J Nurs Sci. 2023 Dec 13;11(1):18-30. doi: 10.1016/j.ijnss.2023.12.007. eCollection 2024 Jan. Int J Nurs Sci. 2023. PMID: 38352282 Free PMC article. Review. - Effects of resistance training and protein supplementation interventions on muscle volume and muscle function: sex differences in humans.
Noh KW, Park S. Noh KW, et al. Phys Act Nutr. 2023 Dec;27(4):15-25. doi: 10.20463/pan.2023.0033. Epub 2023 Dec 31. Phys Act Nutr. 2023. PMID: 38297472 Free PMC article.
References
- Park Y., Park H., Kim J., Hwang H., Jung Y., Kreider R., Lim K. Effects of whey protein supplementation prior to, and following, resistance exercise on body composition and training responses: A randomized double-blind placebo-controlled study. J. Exerc. Nutr. Biochem. 2019;23:34. doi: 10.20463/jenb.2019.0015. - DOI - PMC - PubMed
- Burnley E.C.D., Olson A.N., Sharp R.L., Baier S.M., Alekel D.L. Impact of protein supplements on muscle recovery after exercise-induced muscle soreness. J. Exerc. Sci. Fit. 2010;8:89–96. doi: 10.1016/S1728-869X(10)60014-7. - DOI
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources