Passive immunization of hamsters against experimental infection with the Lyme disease spirochete - PubMed (original) (raw)

Passive immunization of hamsters against experimental infection with the Lyme disease spirochete

R C Johnson et al. Infect Immun. 1986 Sep.

Abstract

Hamsters passively immunized with as little as 0.0125 ml of immune rabbit serum (indirect fluorescent-antibody titer, 1:8,192) were protected from challenge with 1,000 50% infective doses of Borrelia burgdorferi. Cross-protection studies with Minnesota and Connecticut isolates of B. burgdorferi indicated no major differences in their capacity to elicit mutually protective antibodies in rabbits.

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References

    1. Ann Intern Med. 1977 Jun;86(6):685-98 -PubMed
    1. Science. 1982 Jun 18;216(4552):1317-9 -PubMed
    1. J Exp Med. 1982 Nov 1;156(5):1312-24 -PubMed
    1. N Engl J Med. 1983 Mar 31;308(13):733-40 -PubMed
    1. N Engl J Med. 1983 Mar 31;308(13):740-2 -PubMed

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