Expression of MHC antigens by mouse thymic dendritic cells - PubMed (original) (raw)
. 1979 Jun;122(6):2508-15.
- PMID: 376735
Expression of MHC antigens by mouse thymic dendritic cells
R V Rouse et al. J Immunol. 1979 Jun.
Abstract
Thymic epithelial cells express MHC antigens in several different patterns. I-A is present throughout the thymic cortex on dendritic cells. The remainder of the I region and H-2K/D are expressed on dendritic cells apparently only variably in the cortex (at least in some haplotypes). All MHC antigens tested are present in the medulla on epithelial cells; expression on medullary lymphocytes cannot be evaluated. Monoclonal anti-MHC antibodies confirm these results. The significance of these findings to T cell maturation is discussed.
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