Clathrin light chains contain brain-specific insertion sequences and a region of homology with intermediate filaments - PubMed (original) (raw)

Comparative Study

. 1987 Mar;326(6109):154-9.

doi: 10.1038/326154a0.

• PMID: 3821891
• DOI: 10.1038/326154a0

Comparative Study

Clathrin light chains contain brain-specific insertion sequences and a region of homology with intermediate filaments

A P Jackson et al. Nature. 1987 Mar.

Abstract

The primary structures of four bovine clathrin light chains have been determined. Light chains LCa and LCb are homologous proteins encoded by different genes. In the brain the messenger RNA from these genes undergoes differential splicing to yield proteins having centrally inserted brain-specific sequences. A potentially alpha-helical region of the clathrin light chains shows homology with intermediate filament proteins.

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