Phagocytosis of unopsonized zymosan by human monocyte-derived macrophages: maturation and inhibition by mannan - PubMed (original) (raw)

Phagocytosis of unopsonized zymosan by human monocyte-derived macrophages: maturation and inhibition by mannan

D P Speert et al. J Leukoc Biol. 1985 Nov.

Abstract

Human monocyte-derived macrophages phagocytosed zymosan in the absence of serum opsonins. The capacity to ingest zymosan developed after the cells were cultured in vitro for 3 days and was inhibited completely by mannan. We conclude that human monocyte-derived macrophages phagocytose unopsonized zymosan predominantly via mannose receptors.

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