APACHE II: a severity of disease classification system - PubMed (original) (raw)

Comparative Study

. 1985 Oct;13(10):818-29.

• PMID: 3928249

Comparative Study

APACHE II: a severity of disease classification system

W A Knaus et al. Crit Care Med. 1985 Oct.

Abstract

This paper presents the form and validation results of APACHE II, a severity of disease classification system. APACHE II uses a point score based upon initial values of 12 routine physiologic measurements, age, and previous health status to provide a general measure of severity of disease. An increasing score (range 0 to 71) was closely correlated with the subsequent risk of hospital death for 5815 intensive care admissions from 13 hospitals. This relationship was also found for many common diseases. When APACHE II scores are combined with an accurate description of disease, they can prognostically stratify acutely ill patients and assist investigators comparing the success of new or differing forms of therapy. This scoring index can be used to evaluate the use of hospital resources and compare the efficacy of intensive care in different hospitals or over time.

PubMed Disclaimer

Similar articles

• Verification of the Acute Physiology and Chronic Health Evaluation scoring system in a Hong Kong intensive care unit.
  Oh TE, Hutchinson R, Short S, Buckley T, Lin E, Leung D. Oh TE, et al. Crit Care Med. 1993 May;21(5):698-705. doi: 10.1097/00003246-199305000-00013. Crit Care Med. 1993. PMID: 8482091
• Acute physiology and chronic health evaluation (APACHE II) and Medicare reimbursement.
  Wagner DP, Draper EA. Wagner DP, et al. Health Care Financ Rev. 1984;Suppl(Suppl):91-105. Health Care Financ Rev. 1984. PMID: 10311080 Free PMC article.
• Statistical validation of a severity of illness measure.
  Wagner DP, Knaus WA, Draper EA. Wagner DP, et al. Am J Public Health. 1983 Aug;73(8):878-84. doi: 10.2105/ajph.73.8.878. Am J Public Health. 1983. PMID: 6408937 Free PMC article.
• [Prognostic scores in intensive care].
  Unertl K, Kottler BM. Unertl K, et al. Anaesthesist. 1997 Jun;46(6):471-80. doi: 10.1007/s001010050426. Anaesthesist. 1997. PMID: 9297377 Review. German.
• Severity scores in respiratory intensive care: APACHE II predicted mortality better than SAPS II.
  Del Bufalo C, Morelli A, Bassein L, Fasano L, Quarta CC, Pacilli AM, Gunella G. Del Bufalo C, et al. Respir Care. 1995 Oct;40(10):1042-7. Respir Care. 1995. PMID: 10152703 Review.

Cited by

• Association between D-dimer-to-albumin ratio and 28-days all-cause mortality in patients with sepsis.
  Lu J, Fang W, Lei Y, Yang J. Lu J, et al. Sci Rep. 2024 Nov 16;14(1):28361. doi: 10.1038/s41598-024-79911-0. Sci Rep. 2024. PMID: 39550487 Free PMC article.
• Heterogeneous Treatment Effects of High-Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome: A Post Hoc Analysis of the Oscillation for Acute Respiratory Distress Syndrome Treated Early (OSCILLATE) Trial.
  Kobayashi H, Angriman F, Ferguson ND, Adhikari NKJ. Kobayashi H, et al. Crit Care Explor. 2024 Nov 7;6(11):e1178. doi: 10.1097/CCE.0000000000001178. eCollection 2024 Nov. Crit Care Explor. 2024. PMID: 39525347 Free PMC article. Clinical Trial.
• Development and validation of a risk prediction model for feeding intolerance in neurocritical patients with enteral nutrition.
  Yuan R, Liu L, Mi J, Li X, Yang F, Mao S. Yuan R, et al. Front Nutr. 2024 Oct 23;11:1481279. doi: 10.3389/fnut.2024.1481279. eCollection 2024. Front Nutr. 2024. PMID: 39507904 Free PMC article.
• Heart rate variability in acute pancreatitis: a narrative review.
  Liau MYQ, Liau JYJ, Selvakumar SV, Chan KS, Shelat VG. Liau MYQ, et al. Transl Gastroenterol Hepatol. 2024 Aug 21;9:68. doi: 10.21037/tgh-24-22. eCollection 2024. Transl Gastroenterol Hepatol. 2024. PMID: 39503030 Free PMC article. Review.

Publication types

MeSH terms

LinkOut - more resources

• Full Text Sources

  • Ovid Technologies, Inc.

• Other Literature Sources

  • The Lens - Patent Citations Database

• Medical

  • MedlinePlus Health Information