A model of brain abscess: septic homologous blood clot emboli in rats - PubMed (original) (raw)

A model of brain abscess: septic homologous blood clot emboli in rats

H Matsuura et al. J Neurosurg. 1986 Jan.

Abstract

Brain abscesses in rats were produced by intra-arterial injection of septic homologous blood clot emboli. The production rate was 100% and the histopathological features closely resembled those seen in other animal models and in spontaneously occurring brain abscesses in humans. This small-animal model may be useful for systematic study of the development of brain abscesses as well as for evaluation of various therapeutic procedures.

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