[DNAse II from phagocytes in the study of the pathogenesis of systemic lupus erythematosus] - PubMed (original) (raw)
. 1986 Jan-Feb;32(1):32-4.
[Article in Russian]
- PMID: 3953009
[DNAse II from phagocytes in the study of the pathogenesis of systemic lupus erythematosus]
[Article in Russian]
L I Matul'skaia et al. Vopr Med Khim. 1986 Jan-Feb.
Abstract
Activity of acid DNAase (DNAase II) was shown to decrease in neutrophils from peripheric blood of patients with systemic lupus erythematosus as well as in macrophages of liver tissue from mice of the F1(NZB/w) strain during development of the lupus syndrome. Inhibition of the DNAase II activity in phagocytic cells might be among the reasons of accumulation of extracellular highly polymeric DNA in blood of the patients with systemic lupus erythematosus and to play a definite role in pathogenesis of the disease.
Similar articles
- The uptake and degradation of DNA is impaired in macrophages and dendritic cells from NZB/W F(1) mice.
Ogawa Y, Yoshinaga T, Yasuda K, Nishikawa M, Takakura Y. Ogawa Y, et al. Immunol Lett. 2005 Oct 15;101(1):32-40. doi: 10.1016/j.imlet.2005.05.003. Immunol Lett. 2005. PMID: 15979158 - Identification of systemically expanded activated T cell clones in MRL/lpr and NZB/W F1 lupus model mice.
Zhou G, Fujio K, Sadakata A, Okamoto A, Yu R, Yamamoto K. Zhou G, et al. Clin Exp Immunol. 2004 Jun;136(3):448-55. doi: 10.1111/j.1365-2249.2004.02473.x. Clin Exp Immunol. 2004. PMID: 15147346 Free PMC article. - T cell cytokine imbalance towards production of IFN-gamma and IL-10 in NZB/W F1 lupus-prone mice is associated with autoantibody levels and nephritis.
Enghard P, Langnickel D, Riemekasten G. Enghard P, et al. Scand J Rheumatol. 2006 May-Jun;35(3):209-16. doi: 10.1080/03009740500417791. Scand J Rheumatol. 2006. PMID: 16766368 - Anti-nucleosome antibodies and T-cell response in systemic lupus erythematosus.
Fournel S, Muller S. Fournel S, et al. Ann Med Interne (Paris). 2002 Dec;153(8):513-9. Ann Med Interne (Paris). 2002. PMID: 12610425 Review. - Experimental use of murine lupus models.
Peng SL. Peng SL. Methods Mol Med. 2004;102:227-72. doi: 10.1385/1-59259-805-6:227. Methods Mol Med. 2004. PMID: 15286389 Review.
Cited by
- Defects in lysosomal maturation facilitate the activation of innate sensors in systemic lupus erythematosus.
Monteith AJ, Kang S, Scott E, Hillman K, Rajfur Z, Jacobson K, Costello MJ, Vilen BJ. Monteith AJ, et al. Proc Natl Acad Sci U S A. 2016 Apr 12;113(15):E2142-51. doi: 10.1073/pnas.1513943113. Epub 2016 Mar 28. Proc Natl Acad Sci U S A. 2016. PMID: 27035940 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Other Literature Sources
Medical