The use of sample genealogies for studying a selectively neutral m-loci model with recombination - PubMed (original) (raw)
The use of sample genealogies for studying a selectively neutral m-loci model with recombination
N Kaplan et al. Theor Popul Biol. 1985 Dec.
Abstract
A selectively neutral m-loci model with recombination is studied. A general method is developed to calculate the variance of the number of segregating sites in samples of arbitrary size and the m-loci homozygosity. The method is based on properties of the genealogy of the sample rather than diffusion approximations. To demonstrate the scope of the method several calculations are presented.
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