Complete transcription by the transcriptase of vesicular stomatitis virus - PubMed (original) (raw)

Complete transcription by the transcriptase of vesicular stomatitis virus

D H Bishop. J Virol. 1971 Apr.

Abstract

Vesicular stomatitis virus (VSV) transcriptase completely transcribes the VSV genome into messenger-size ribonucleic acid (RNA) species. The replicating complexes of template and product RNA, generated in vitro by VSV transcriptase, exhibit a mass parity between product and template molecules. Purified product RNA, after annealing to small amounts of viral RNA, rendered 92% of the viral RNA ribonuclease-resistant. It is calculated that, under optimal conditions, 60 min is required before the VSV genome is completely transcribed.

PubMed Disclaimer

References

    1. Proc Natl Acad Sci U S A. 1970 Jun;66(2):572-6 - PubMed
    1. Nature. 1970 Mar 7;225(5236):944-5 - PubMed
    1. Proc Natl Acad Sci U S A. 1963 May;49(5):654-62 - PubMed
    1. J Mol Biol. 1967 Jun 28;26(3):373-87 - PubMed
    1. Virology. 1970 Dec;42(4):946-57 - PubMed

MeSH terms

Substances

LinkOut - more resources