The nucleotide sequence complexity of avian tumor virus RNA - PubMed (original) (raw)
The nucleotide sequence complexity of avian tumor virus RNA
M A Billeter et al. Proc Natl Acad Sci U S A. 1974 Sep.
Abstract
The nucleotide sequence complexity of 60-70S RNA of Rous sarcoma virus was determined from the molar yields of 11 pure oligonucleotides of known chain length, obtained from [(32)P]RNA of Rous sarcoma virus by T1 RNase digestion and two-dimensional polyacrylamide gel electrophoresis. We calculate an apparent chain length of about 9800 nucleotides, corresponding to a molecular weight of 3.4 x 10(6). Assuming the molecular weight of 60-70S RNA of Rous sarcoma virus to be about 10(7), our data suggest that the virus genome consists of identical, or very similar, nucleotide sequences repeated three to four times.
Similar articles
- Evidence for common nucleotide sequences in the RNA subunits comprising Rous sarcoma virus 70 S RNA.
Quade K, Smith RE, Nichols JL. Quade K, et al. Virology. 1974 Sep;61(1):287-91. doi: 10.1016/0042-6822(74)90263-3. Virology. 1974. PMID: 4370009 No abstract available. - Poly(riboadenylic acid) and adjacent nucleotides in Rous sarcoma virus RNA.
Quade K, Smith RE, Nichols JL. Quade K, et al. Virology. 1974 Nov;62(1):60-70. doi: 10.1016/0042-6822(74)90303-1. Virology. 1974. PMID: 4370608 No abstract available. - Characterization of the low-molecular-weight RNAs associated with the 70S RNA of Rous sarcoma virus.
Faras AJ, Garapin AC, Levinson WE, Bishop JM, Goodman HM. Faras AJ, et al. J Virol. 1973 Aug;12(2):334-42. doi: 10.1128/JVI.12.2.334-342.1973. J Virol. 1973. PMID: 4355935 Free PMC article. - Small RNAs of Rous sarcoma virus: characterization by two-dimensional polyacrylamide gel electrophoresis and fingerprint analysis.
Sawyer RC, Dahlberg JE. Sawyer RC, et al. J Virol. 1973 Dec;12(6):1226-37. doi: 10.1128/JVI.12.6.1226-1237.1973. J Virol. 1973. PMID: 4357505 Free PMC article. - Qualitative and quantitative measurements of oligonucleotides in gene therapy: Part II in vivo models.
Tewary HK, Iversen PL. Tewary HK, et al. J Pharm Biomed Anal. 1997 May;15(8):1127-35. doi: 10.1016/s0731-7085(97)01942-0. J Pharm Biomed Anal. 1997. PMID: 9215965 Review.
Cited by
- Terminal redundancy and the origin of replication of Rous sarcoma virus RNA.
Coffin JM, Haseltine WA. Coffin JM, et al. Proc Natl Acad Sci U S A. 1977 May;74(5):1908-12. doi: 10.1073/pnas.74.5.1908. Proc Natl Acad Sci U S A. 1977. PMID: 68472 Free PMC article. - Ribonucleotide sequence homology among avian oncornaviruses.
Shoyab M, Baluda MA. Shoyab M, et al. J Virol. 1975 Jan;17(1):106-113. doi: 10.1128/JVI.17.1.106-113.1976. J Virol. 1975. PMID: 173876 Free PMC article. - Evidence for the identity of shared 5'-terminal sequences between genome RNA and subgenomic mRNA's of B77 avian sarcoma virus.
Stoltzfus CM, Kuhnert LK. Stoltzfus CM, et al. J Virol. 1979 Nov;32(2):536-45. doi: 10.1128/JVI.32.2.536-545.1979. J Virol. 1979. PMID: 228077 Free PMC article. - Independent regulation of endogenous and exogenous avian RNA tumor virus genes.
Hayward WS, Hanafusa H. Hayward WS, et al. Proc Natl Acad Sci U S A. 1976 Jul;73(7):2259-63. doi: 10.1073/pnas.73.7.2259. Proc Natl Acad Sci U S A. 1976. PMID: 181750 Free PMC article.
References
- Proc Natl Acad Sci U S A. 1965 Jul;54(1):137-44 - PubMed
- Biochemistry. 1968 Feb;7(2):865-74 - PubMed
- Proc Natl Acad Sci U S A. 1968 Aug;60(4):1511-8 - PubMed
- J Gen Virol. 1969 Apr;4(3):449-52 - PubMed
- Nature. 1969 Sep 6;223(5210):1009-14 - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources