X-ray diffraction studies of nucleohistone: a polyhelical model of chromosome organization - PubMed (original) (raw)
X-ray diffraction studies of nucleohistone: a polyhelical model of chromosome organization
J A Subirana et al. Proc Natl Acad Sci U S A. 1974 May.
Abstract
The possibility that nucleohistone is constituted by a helical arrangement of DNA molecules is analyzed in this paper. A polyhelical model of nucleohistone in plectanemic double coils of variable dimensions is found to be compatible with the x-ray diffraction results obtained in this and other laboratories. The radius of the coils varies between 35 and 45 A, whereas the pitch varies between 200 and 120 A. Another part of nucleohistone is much less coiled and contributes to the "background" scattering of the sample. This model is compatible with a lampbrush organization of the chromosome.
Similar articles
- Molecular arrangement of DNA in nucleohistone.
Basu S. Basu S. Z Naturforsch C Biosci. 1975 Sep-Oct;30(5):575-85. doi: 10.1515/znc-1975-9-1005. Z Naturforsch C Biosci. 1975. PMID: 129987 - X-ray diffraction studies on oriented nucleohistone gels.
Pardon JF, Richards BM, Cotter RI. Pardon JF, et al. Cold Spring Harb Symp Quant Biol. 1974;38:75-81. doi: 10.1101/sqb.1974.038.01.010. Cold Spring Harb Symp Quant Biol. 1974. PMID: 4524787 No abstract available. - A super-coil model for nucleohistone.
Pardon JF, Wilkins MH. Pardon JF, et al. J Mol Biol. 1972 Jul 14;68(1):115-24. doi: 10.1016/0022-2836(72)90267-7. J Mol Biol. 1972. PMID: 5050359 No abstract available. - [Planar model of nucleosome and chromatin structure of high orders].
Priiatkina TN. Priiatkina TN. Biokhimiia. 1977 Nov;42(11):1923-33. Biokhimiia. 1977. PMID: 338036 Review. Russian. - [Structure of nucleohistone and its biological significance, with special emphasis on inhibition of RNA synthesis in vitro].
Kurashina Y, Oba Y. Kurashina Y, et al. Tanpakushitsu Kakusan Koso. 1970 Jan;15(1):2-9. Tanpakushitsu Kakusan Koso. 1970. PMID: 4908988 Review. Japanese. No abstract available.
Cited by
- Chromatin model calculations: Arrays of spherical nu bodies.
Carlson RD, Olins DE. Carlson RD, et al. Nucleic Acids Res. 1976 Jan;3(1):89-100. doi: 10.1093/nar/3.1.89. Nucleic Acids Res. 1976. PMID: 1250708 Free PMC article. - Chromatin and nucleosome structure.
Mandel R, Fasman GD. Mandel R, et al. Nucleic Acids Res. 1976 Aug;3(8):1839-55. doi: 10.1093/nar/3.8.1839. Nucleic Acids Res. 1976. PMID: 967679 Free PMC article.
References
- Nature. 1967 Jul 29;215(5100):508-9 - PubMed
- J Mol Biol. 1971 Feb 14;55(3):325-36 - PubMed
- J Cell Biol. 1972 Jun;53(3):715-36 - PubMed
- J Mol Biol. 1972 Jul 14;68(1):115-24 - PubMed
- Eur J Biochem. 1972 Dec 18;31(3):474-82 - PubMed
MeSH terms
Substances
LinkOut - more resources
Full Text Sources