Cutaneous masking. II. Geometry of excitatory andinhibitory receptive fields of single units in somatosensory cortex of the cat - PubMed (original) (raw)
Cutaneous masking. II. Geometry of excitatory andinhibitory receptive fields of single units in somatosensory cortex of the cat
S E Laskin et al. J Neurophysiol. 1979 Jul.
Abstract
1. The responses of single neurons in the primary somatosensory cortex of the cat to brief air-pulse stimuli were quantitatively examined. These controlled natural stimuli activated almost exclusively rapidly adapting hair units which, on systematic movement of the stimulus through the receptive field, gave unit-response profiles that showed the classical unimodal tent-shaped distribution. 2. Conditioning stimulus-induced inhibition of a response evoked by a fixed test stimulus was measured by systematically moving the conditioning stimulus through the receptive field. The spatial distribution of in-field inhibitory activity was unimodal and highly covariant with that of the conditioning excitation, the peak inhibition corresponding to the functional center of the excitatory receptive field. 3. Nearly one-half of the units studied evidenced inhibition extending beyond the excitatory receptive field, forming a "surround" inhibitory region; but these were usually restricted areas with rather weak inhibitory effects. 4. Time-course measuring revealed, on the average, inhibition effects measureable from 10 ms before to some 70 ms following conditioning stimulation, with peak inhibition delayed some 10--15 ms from the conditioning stimulus onset. We showed the backward inhibition, occurring with the test stimulus delivered before the onset of the conditioning stimulus, to be a property of the test response duration. Inhibition measured in the surround areas had essentially the same time course as the inhibition calculated from measurements made within the receptive fields. 5. The spatial and temporal profiles of the excitatory and inhibitory cortical unitary activity are thus very similar to the parametric features of psychophysical enhancement and masking. These findings suggest that the excitatory and inhibitory activities related to individual stimuli interact in multipoint stimulus paradigms so that simple unimodal composite profiles are synthesized.
Similar articles
- Cutaneous masking. I. Psychophysical observations on interactions of multipoint stimuli in man.
Laskin SE, Spencer WA. Laskin SE, et al. J Neurophysiol. 1979 Jul;42(4):1048-60. doi: 10.1152/jn.1979.42.4.1048. J Neurophysiol. 1979. PMID: 573312 - Removal of GABAergic inhibition alters subthreshold input in neurons in forepaw barrel subfield (FBS) in rat first somatosensory cortex (SI) after digit stimulation.
Li CX, Callaway JC, Waters RS. Li CX, et al. Exp Brain Res. 2002 Aug;145(4):411-28. doi: 10.1007/s00221-002-1124-7. Epub 2002 Jul 3. Exp Brain Res. 2002. PMID: 12172653 - Spatial and temporal features of afferent inhibition of thalamocortical relay cells.
Jänig W, Spencer WA, Younkin SG. Jänig W, et al. J Neurophysiol. 1979 Sep;42(5):1450-60. doi: 10.1152/jn.1979.42.5.1450. J Neurophysiol. 1979. PMID: 490202 - Time course of forward masking tuning curves in cat primary auditory cortex.
Brosch M, Schreiner CE. Brosch M, et al. J Neurophysiol. 1997 Feb;77(2):923-43. doi: 10.1152/jn.1997.77.2.923. J Neurophysiol. 1997. PMID: 9065859 - Quantitative sensory assessment in toxicology and occupational medicine: applications, theory, and critical appraisal.
Maurissen JP. Maurissen JP. Toxicol Lett. 1988 Oct;43(1-3):321-43. doi: 10.1016/0378-4274(88)90036-7. Toxicol Lett. 1988. PMID: 3051524 Review.
Cited by
- Interrupted processing of paired somatosensory stimuli in short interstimulus intervals: role of thalamo-cortical oscillations.
Tepe N, Boran HE, Gedük S, Dileköz E, Ulusoy İ, Bolay H. Tepe N, et al. Turk J Med Sci. 2022 Aug;52(4):1371-1377. doi: 10.55730/1300-0144.5444. Epub 2022 Aug 10. Turk J Med Sci. 2022. PMID: 36326364 Free PMC article. - Tactile suppression stems from specific sensorimotor predictions.
Fuehrer E, Voudouris D, Lezkan A, Drewing K, Fiehler K. Fuehrer E, et al. Proc Natl Acad Sci U S A. 2022 May 17;119(20):e2118445119. doi: 10.1073/pnas.2118445119. Epub 2022 May 9. Proc Natl Acad Sci U S A. 2022. PMID: 35533281 Free PMC article. - Sensory Processing in the Dorsolateral Striatum: The Contribution of Thalamostriatal Pathways.
Alloway KD, Smith JB, Mowery TM, Watson GDR. Alloway KD, et al. Front Syst Neurosci. 2017 Jul 25;11:53. doi: 10.3389/fnsys.2017.00053. eCollection 2017. Front Syst Neurosci. 2017. PMID: 28790899 Free PMC article. - Chronic recordings reveal tactile stimuli can suppress spontaneous activity of neurons in somatosensory cortex of awake and anesthetized primates.
Qi HX, Reed JL, Franca JG, Jain N, Kajikawa Y, Kaas JH. Qi HX, et al. J Neurophysiol. 2016 Apr;115(4):2105-23. doi: 10.1152/jn.00634.2015. Epub 2016 Feb 24. J Neurophysiol. 2016. PMID: 26912593 Free PMC article. - Early and moderate sensory stimulation exerts a protective effect on perilesion representations of somatosensory cortex after focal ischemic damage.
Xerri C, Zennou-Azogui Y. Xerri C, et al. PLoS One. 2014 Jun 10;9(6):e99767. doi: 10.1371/journal.pone.0099767. eCollection 2014. PLoS One. 2014. PMID: 24914807 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Miscellaneous