Clinical and manometric findings in benign peptic strictures of the esophagus - PubMed (original) (raw)

Clinical and manometric findings in benign peptic strictures of the esophagus

G Ahtaridis et al. Dig Dis Sci. 1979 Nov.

Abstract

To determine the possible factors that may contribute to the development of peptic stricture of the esophagus, clinical and manometric features were compared in patients with symptomatic gastroesophageal reflux and those with peptic strictures of the esophagus. Patients with stricture were older and had a longer duration of heartburn than patients without a stricture. Most importantly, patients with stricture had a more marked decrease in lower esophageal sphincter (LES) pressure, 4.9 +/- 0.5 mm Hg, than patients without a stricture, 7.5 +/- 0.6 mm Hg, P less than 0.01. The LES pressure in all patients with stricture was below 8 mm Hg, and did not overlap with normal values. Patients with stricture had either a nonspecific motor abnormality of aperistalsis (64%), compared to patients with symptomatic reflux (32%), P less than 0.05. Thus, peptic stricture of the esophagus is commonly associated with a long duration of reflux symptoms in patients with a very low LES pressure and esophageal motor disorder.

PubMed Disclaimer

Similar articles

• Esophageal function in patients with reflux-induced strictures and its relevance to surgical treatment.
  Zaninotto G, DeMeester TR, Bremner CG, Smyrk TC, Cheng SC. Zaninotto G, et al. Ann Thorac Surg. 1989 Mar;47(3):362-70. doi: 10.1016/0003-4975(89)90374-3. Ann Thorac Surg. 1989. PMID: 2930301
• Effect of dilatation of peptic esophageal strictures on gastroesophageal reflux, dysphagia, and stricture diameter.
  Penagini R, Al Dabbagh M, Misiewicz JJ, Evans PF, Trotman IF. Penagini R, et al. Dig Dis Sci. 1988 Apr;33(4):389-92. doi: 10.1007/BF01536019. Dig Dis Sci. 1988. PMID: 3349883
• Short esophagus and esophageal stricture.
  Hoang CD, Koh PS, Maddaus MA. Hoang CD, et al. Surg Clin North Am. 2005 Jun;85(3):433-51. doi: 10.1016/j.suc.2005.01.019. Surg Clin North Am. 2005. PMID: 15927642 Review.
• Esophageal function in systemic sclerosis: a prospective evaluation of motility and acid reflux in 36 patients.
  Yarze JC, Varga J, Stampfl D, Castell DO, Jimenez SA. Yarze JC, et al. Am J Gastroenterol. 1993 Jun;88(6):870-6. Am J Gastroenterol. 1993. PMID: 8503383
• Surgery for peptic strictures.
  Mamazza J, Schlachta CM, Poulin EC. Mamazza J, et al. Gastrointest Endosc Clin N Am. 1998 Apr;8(2):399-413. Gastrointest Endosc Clin N Am. 1998. PMID: 9583013 Review.

Cited by

• Effects of omeprazole on mechanisms of gastroesophageal reflux in childhood.
  Cucchiara S, Minella R, Campanozzi A, Salvia G, Borrelli O, Ciccimarra E, Emiliano M. Cucchiara S, et al. Dig Dis Sci. 1997 Feb;42(2):293-9. doi: 10.1023/a:1018853516206. Dig Dis Sci. 1997. PMID: 9052509 Clinical Trial.
• Cycling, a manometric phenomenon due to repetitive episodes of gastroesophageal reflux and clearance.
  Shay SS, Eggli D, Oliver G, Peura DA, Johnson LF. Shay SS, et al. Dig Dis Sci. 1989 Sep;34(9):1340-8. doi: 10.1007/BF01538066. Dig Dis Sci. 1989. PMID: 2766900
• Does healing of esophagitis improve esophageal motor function?
  Eckardt VF. Eckardt VF. Dig Dis Sci. 1988 Feb;33(2):161-5. doi: 10.1007/BF01535727. Dig Dis Sci. 1988. PMID: 3338364
• Precipitating causes of acid reflux episodes in ambulant patients with gastro-oesophageal reflux disease.
  Barham CP, Gotley DC, Mills A, Alderson D. Barham CP, et al. Gut. 1995 Apr;36(4):505-10. doi: 10.1136/gut.36.4.505. Gut. 1995. PMID: 7737554 Free PMC article.

References

1. 1. Am J Dig Dis. 1978 Jun;23(6):498-509 - PubMed
2. 1. Surg Gynecol Obstet. 1973 Apr;136(4):564-6 - PubMed
3. 1. Ann Thorac Surg. 1972 Jun;13(6):543-51 - PubMed
4. 1. Gastroenterology. 1970 Feb;58(2):175-84 - PubMed
5. 1. Gastroenterology. 1976 Aug;71(2):328-9 - PubMed

MeSH terms