Fertility and sibship size in a psychiatric patient population. A comparison with national census data - PubMed (original) (raw)

• Reduced Fertility and Fecundity among Patients with Bipolar I Disorder and Schizophrenia in Egypt.
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• Large recurrent microdeletions associated with schizophrenia.
  Stefansson H, Rujescu D, Cichon S, Pietiläinen OP, Ingason A, Steinberg S, Fossdal R, Sigurdsson E, Sigmundsson T, Buizer-Voskamp JE, Hansen T, Jakobsen KD, Muglia P, Francks C, Matthews PM, Gylfason A, Halldorsson BV, Gudbjartsson D, Thorgeirsson TE, Sigurdsson A, Jonasdottir A, Jonasdottir A, Bjornsson A, Mattiasdottir S, Blondal T, Haraldsson M, Magnusdottir BB, Giegling I, Möller HJ, Hartmann A, Shianna KV, Ge D, Need AC, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Paunio T, Toulopoulou T, Bramon E, Di Forti M, Murray R, Ruggeri M, Vassos E, Tosato S, Walshe M, Li T, Vasilescu C, Mühleisen TW, Wang AG, Ullum H, Djurovic S, Melle I, Olesen J, Kiemeney LA, Franke B; GROUP; Sabatti C, Freimer NB, Gulcher JR, Thorsteinsdottir U, Kong A, Andreassen OA, Ophoff RA, Georgi A, Rietschel M, Werge T, Petursson H, Goldstein DB, Nöthen MM, Peltonen L, Collier DA, St Clair D, Stefansson K. Stefansson H, et al. Nature. 2008 Sep 11;455(7210):232-6. doi: 10.1038/nature07229. Nature. 2008. PMID: 18668039 Free PMC article.
• At issue: is natural selection rendering schizophrenia less severe?
  McGlashan TH. McGlashan TH. Schizophr Bull. 2006 Jul;32(3):428-9. doi: 10.1093/schbul/sbj081. Epub 2006 May 17. Schizophr Bull. 2006. PMID: 16707775 Free PMC article. No abstract available.
• Paternal age and risk of schizophrenia in adult offspring.
  Brown AS, Schaefer CA, Wyatt RJ, Begg MD, Goetz R, Bresnahan MA, Harkavy-Friedman J, Gorman JM, Malaspina D, Susser ES. Brown AS, et al. Am J Psychiatry. 2002 Sep;159(9):1528-33. doi: 10.1176/appi.ajp.159.9.1528. Am J Psychiatry. 2002. PMID: 12202273 Free PMC article.
• Mitochondrial genetic analyses suggest selection against maternal lineages in bipolar affective disorder.
  Kirk R, Furlong RA, Amos W, Cooper G, Rubinsztein JS, Walsh C, Paykel ES, Rubinsztein DC. Kirk R, et al. Am J Hum Genet. 1999 Aug;65(2):508-18. doi: 10.1086/302507. Am J Hum Genet. 1999. PMID: 10417293 Free PMC article.