Antigenic differences between macrophages and lymphocytes - PubMed (original) (raw)

• PMID: 5477728
• PMCID: PMC1712815

Antigenic differences between macrophages and lymphocytes

A W Marsman et al. Clin Exp Immunol. 1970 Jun.

Abstract

Antisera against guinea-pig lymphocytes and guinea-pig macrophages were prepared by injecting rabbits with purified blood lymphocytes or peritoneal macrophages. Both antisera contained antibodies of at least two different specificities, one reacting with an antigen common to lymphocytes and macrophages and one specific for either lymphocytes or macrophages.

Opsonic adherence and phagocytosis of sensitized red cells by macrophages were inhibited by the anti-macrophage serum. The anti-lymphocyte serum showed no such inhibition, when previously absorbed with macrophages.

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