Influence of delta infection on severity of hepatitis B - PubMed (original) (raw)
. 1982 Oct 30;2(8305):945-7.
doi: 10.1016/s0140-6736(82)90156-8.
P Farci, G Verme, F Caredda, A Cargnel, N Caporaso, P Dentico, C Trepo, P Opolon, A Gimson, D Vergani, R Williams, M Rizzetto
- PMID: 6127458
- DOI: 10.1016/s0140-6736(82)90156-8
Influence of delta infection on severity of hepatitis B
A Smedile et al. Lancet. 1982.
Abstract
The prevalence of serum markers of primary delta infection was determined in 532 patients with acute benign hepatitis B seen in Italy, and in 111 patients with fulminant hepatitis B seen in Italy, France and England. Patients with fulminant hepatitis had significantly higher prevalence of delta markers (43/111, 39%) than did those with benign hepatitis (101/532, 19%). In 25 of the 43 patients with delta-positive fulminant hepatitis, serum markers indicated a primary hepatitis B infection while in the remaining 18, IgM antibody to hepatitis B core antigen was absent, indicating that hepatitis B preceded superinfection with the delta agent. The increased morbidity of HBsAg hepatitis with delta infection may result from the cumulative simultaneous exposure to hepatitis B virus and delta, or from superinfection of HBsAg carriers with delta.
Similar articles
- Fulminant B viral hepatitis: role of delta agent.
Govindarajan S, Chin KP, Redeker AG, Peters RL. Govindarajan S, et al. Gastroenterology. 1984 Jun;86(6):1417-20. Gastroenterology. 1984. PMID: 6714570 - Delta hepatitis in inapparent carriers of hepatitis B surface antigen. A disease simulating acute hepatitis B progressive to chronicity.
Farci P, Smedile A, Lavarini C, Piantino P, Crivelli O, Caporaso N, Toti M, Bonino F, Rizzetto M. Farci P, et al. Gastroenterology. 1983 Sep;85(3):669-73. Gastroenterology. 1983. PMID: 6873613 - Viral markers of hepatitis.
Velasco M. Velasco M. Lab Res Methods Biol Med. 1983;7:103-17. Lab Res Methods Biol Med. 1983. PMID: 6413796 Review. No abstract available. - Treatment of hepatitis Delta.
Wedemeyer H, Hardtke S, Manns MP. Wedemeyer H, et al. Clin Liver Dis (Hoboken). 2013 Dec 20;2(6):237-239. doi: 10.1002/cld.254. eCollection 2013 Dec. Clin Liver Dis (Hoboken). 2013. PMID: 30992871 Free PMC article. Review. No abstract available.
Cited by
- Hepatitis Delta Virus and Hepatocellular Carcinoma.
Lombardo D, Franzè MS, Caminiti G, Pollicino T. Lombardo D, et al. Pathogens. 2024 Apr 27;13(5):362. doi: 10.3390/pathogens13050362. Pathogens. 2024. PMID: 38787214 Free PMC article. Review. - The Forgotten Virus, Hepatitis D: A Review of Epidemiology, Diagnosis, and Current Treatment Strategies.
Khattak A, Vongsavath T, Haque L, Narwan A, Gish RG. Khattak A, et al. J Clin Exp Hepatol. 2024 Sep-Oct;14(5):101395. doi: 10.1016/j.jceh.2024.101395. Epub 2024 Mar 9. J Clin Exp Hepatol. 2024. PMID: 38617106 Review. - Diagnostic Efficacy of Serological Antibody Detection Tests for Hepatitis Delta Virus: A Systematic Review and Meta-Analysis.
Pan Z, Chen S, Xu L, Gao Y, Cao Y, Fan Z, Tian Y, Zhang X, Duan Z, Ren F. Pan Z, et al. Viruses. 2023 Nov 29;15(12):2345. doi: 10.3390/v15122345. Viruses. 2023. PMID: 38140586 Free PMC article. Review. - Cellular Factors Involved in the Hepatitis D Virus Life Cycle.
Thiyagarajah K, Basic M, Hildt E. Thiyagarajah K, et al. Viruses. 2023 Aug 3;15(8):1687. doi: 10.3390/v15081687. Viruses. 2023. PMID: 37632029 Free PMC article. Review. - An Insight Into the Factors Affecting the Prevalence and Natural History of Hepatitis D.
Abbas Z, Abbas M. Abbas Z, et al. Cureus. 2023 Aug 12;15(8):e43362. doi: 10.7759/cureus.43362. eCollection 2023 Aug. Cureus. 2023. PMID: 37593072 Free PMC article. Review.
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical