Receptors for pyelonephritogenic Escherichia coli in primates - PubMed (original) (raw)

Receptors for pyelonephritogenic Escherichia coli in primates

J A Roberts et al. J Urol. 1984 Jan.

Abstract

P-fimbriated Escherichia coli adhere to uroepithelial cells of monkeys by binding to receptors which are identical or very similar to those of man. In atraumatic experimental infections of monkeys, a P-fimbriated Escherichia coli strain induced ureteral malfunction with subsequent pyelonephritis. A non-P-fimbriated Escherichia coli strain did not. Thus, P-fimbriation of Escherichia coli represents a true virulence factor in the acquisition of pyelonephritis.

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