Distinctive sequence of human mitochondrial ribosomal RNA genes - PubMed (original) (raw)

Comparative Study

. 1980 Jul 31;286(5772):460-7.

doi: 10.1038/286460a0.

Comparative Study

Distinctive sequence of human mitochondrial ribosomal RNA genes

I C Eperon et al. Nature. 1980.

Abstract

The nucleotide sequence spanning the ribosomal RNA (rRNA) genes of cloned human mitochondrial DNA reveals an extremely compact genome organization wherein the putative tRNA genes are probably 'butt-jointed' around the two rRNA genes. The sequences of the rRNA genes are significantly homologous in some regions to eukaryotic and prokaryotic sequences, but distinctive; the tRNA genes also have unusual nucleotide sequences. It seems that human mitochondria did not originate from recognizable relatives of present day organisms.

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