Ultrasensitive stain for proteins in polyacrylamide gels shows regional variation in cerebrospinal fluid proteins - PubMed (original) (raw)
Ultrasensitive stain for proteins in polyacrylamide gels shows regional variation in cerebrospinal fluid proteins
C R Merril et al. Science. 1981.
Abstract
A new silver stain for electrophoretically separated polypeptides can be rapidly and easily used and can detect as little as 0.01 nanogram of protein per square millimeter. When employed with two-dimensional electrophoresis, it should permit qualitative and quantitative characterization of protein distributions in body fluids and tissues. It has been used to demonstrate regional variations in cerebrospinal fluid proteins.
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