Genetic transformation of putative cariogenic properties in Streptococcus mutans - PubMed (original) (raw)

Genetic transformation of putative cariogenic properties in Streptococcus mutans

D Perry et al. Infect Immun. 1983 Aug.

Abstract

Rough colonial morphology and bacteriocin production, two properties which may be associated with the cariogenicity of Streptococcus mutans, were transformed into several strain GS-5 mutants defective in each respective property. Transformation was determined by observing the frequency of cotransfer of these properties with different reference markers. The rough colonial transformants were identical to the parental GS-5 strain with respect to ability to synthesize water-insoluble glucans and undergo in vitro sucrose-dependent colonization of glass surfaces. Alterations in the growth medium and the concentration of the initial cell inoculum resulted in an approximate 10-fold increase in the frequency of transformation of strain GS-5 compared to previous observations.

PubMed Disclaimer

Similar articles

• Comparison of glucan-binding proteins in cariogenicity of Streptococcus mutans.
  Matsumoto-Nakano M, Fujita K, Ooshima T. Matsumoto-Nakano M, et al. Oral Microbiol Immunol. 2007 Feb;22(1):30-5. doi: 10.1111/j.1399-302X.2007.00318.x. Oral Microbiol Immunol. 2007. PMID: 17241168
• Virulence factors of Streptococcus mutans and dental caries prevention.
  Hamada S, Koga T, Ooshima T. Hamada S, et al. J Dent Res. 1984 Mar;63(3):407-11. doi: 10.1177/00220345840630031001. J Dent Res. 1984. PMID: 6230378
• [Evaluation of cariogenic potential of Streptococcus mutans isolated from caries-free and -active persons: abilities to synthesize water-soluble and -insoluble glucans].
  Huang X, Liu T, Yang J, Chen Z, Liu J. Huang X, et al. Hua Xi Kou Qiang Yi Xue Za Zhi. 2000 Dec;18(6):419-21. Hua Xi Kou Qiang Yi Xue Za Zhi. 2000. PMID: 12539476 Chinese.
• Biology, immunology, and cariogenicity of Streptococcus mutans.
  Hamada S, Slade HD. Hamada S, et al. Microbiol Rev. 1980 Jun;44(2):331-84. doi: 10.1128/mr.44.2.331-384.1980. Microbiol Rev. 1980. PMID: 6446023 Free PMC article. Review. No abstract available.
• Genetic analysis of Streptococcus mutans virulence.
  Curtiss R 3rd. Curtiss R 3rd. Curr Top Microbiol Immunol. 1985;118:253-77. doi: 10.1007/978-3-642-70586-1_14. Curr Top Microbiol Immunol. 1985. PMID: 2932305 Review. No abstract available.

Cited by

• LuxS-based signaling affects Streptococcus mutans biofilm formation.
  Yoshida A, Ansai T, Takehara T, Kuramitsu HK. Yoshida A, et al. Appl Environ Microbiol. 2005 May;71(5):2372-80. doi: 10.1128/AEM.71.5.2372-2380.2005. Appl Environ Microbiol. 2005. PMID: 15870324 Free PMC article.
• Role of serotype-specific polysaccharide in the resistance of Streptococcus mutans to phagocytosis by human polymorphonuclear leukocytes.
  Tsuda H, Yamashita Y, Toyoshima K, Yamaguchi N, Oho T, Nakano Y, Nagata K, Koga T. Tsuda H, et al. Infect Immun. 2000 Feb;68(2):644-50. doi: 10.1128/IAI.68.2.644-650.2000. Infect Immun. 2000. PMID: 10639428 Free PMC article.
• Role of the charged tail in localization of a surface protein antigen of Streptococcus mutans.
  Murakami Y, Yamashita Y, Nakano Y, Ito HO, Yu H, Koga T. Murakami Y, et al. Infect Immun. 1997 Apr;65(4):1531-5. doi: 10.1128/iai.65.4.1531-1535.1997. Infect Immun. 1997. PMID: 9119499 Free PMC article.
• Defects in D-alanyl-lipoteichoic acid synthesis in Streptococcus mutans results in acid sensitivity.
  Boyd DA, Cvitkovitch DG, Bleiweis AS, Kiriukhin MY, Debabov DV, Neuhaus FC, Hamilton IR. Boyd DA, et al. J Bacteriol. 2000 Nov;182(21):6055-65. doi: 10.1128/JB.182.21.6055-6065.2000. J Bacteriol. 2000. PMID: 11029425 Free PMC article.
• Genes involved in bacitracin resistance in Streptococcus mutans.
  Tsuda H, Yamashita Y, Shibata Y, Nakano Y, Koga T. Tsuda H, et al. Antimicrob Agents Chemother. 2002 Dec;46(12):3756-64. doi: 10.1128/AAC.46.12.3756-3764.2002. Antimicrob Agents Chemother. 2002. PMID: 12435673 Free PMC article. Review.

References

1. 1. Infect Immun. 1974 Jul;10(1):189-96 - PubMed
2. 1. Infect Immun. 1975 Apr;11(4):656-64 - PubMed
3. 1. Annu Rev Med. 1975;26:121-36 - PubMed
4. 1. Infect Immun. 1975 Oct;12(4):738-49 - PubMed
5. 1. J Bacteriol. 1977 Jan;129(1):351-7 - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Atypon
  • Europe PubMed Central
  • PubMed Central

• Other Literature Sources

  • The Lens - Patent Citations Database

• Medical

  • MedlinePlus Health Information