In vivo sequence requirements of the SV40 early promotor region - PubMed (original) (raw)

. 1981 Mar 26;290(5804):304-10.

doi: 10.1038/290304a0.

• PMID: 6259538
• DOI: 10.1038/290304a0

In vivo sequence requirements of the SV40 early promotor region

C Benoist et al. Nature. 1981.

Abstract

To investigate the sequences necessary for proper initiation of transcription of SV40 early genes, we have constructed several deletion mutants in the promoter region. The TATA box region is apparently involved in fixing initiation precisely within a narrow area, but is dispensable for gene expression, while the sequences located more than 150 base pairs upstream are indispensable.

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