DNA sequences similar to those around the simian virus 40 origin of replication are present in the monkey genome - PubMed (original) (raw)
Comparative Study
DNA sequences similar to those around the simian virus 40 origin of replication are present in the monkey genome
T F McCutchan et al. Proc Natl Acad Sci U S A. 1981 Jan.
Abstract
We report the molecular cloning of African green monkey genomic DNA segments that include regions of homology to the origin of replication of simian virus 40 (SV40). Three clearly different cloned segments 14 to 17 kilobase pairs (kb) long were isolated from a genomic library in lambda phage. We estimate that each of the three is repeated fewer than four times in the monkey genome. The SV40-like regions represent a small portion of the cloned segments, and these regions cross hybridize only weakly with one another. One of the three segments is described here in detail. Although the entire segment occurs only once or twice in the monkey genome, it contains DNA sequences (other than the SV40-like sequences) that are repeated elsewhere in the genome including in the other two cloned segments. The homology to SV40 is contained within about 300 base pairs of monkey DNA and is limited to the region around the viral replication origin. The nucleotide sequence of the SV40-like region was determined. It contains a large number of short stretches homologous to three specific noncoding domains around the SV40 origin of replication: the 27-base-pair region of dyad symmetry, the first set of (short) repeats that occur just on the late side of the origin, and, further in the late direction, the two 72-base-pair-long repeats. Although these components are grouped in the monkey DNA, as they are in SV40 DNA, their relative juxtaposition is scrambled.
Similar articles
- Transcription from SV 40-like monkey DNA sequences.
Saffer JD, Singer MF. Saffer JD, et al. Nucleic Acids Res. 1984 Jun 11;12(11):4769-88. doi: 10.1093/nar/12.11.4769. Nucleic Acids Res. 1984. PMID: 6330683 Free PMC article. - Three segments from the monkey genome that hybridize to simian virus 40 have common structural elements.
Queen C, Lord ST, McCutchan TF, Singer MF. Queen C, et al. Mol Cell Biol. 1981 Dec;1(12):1061-8. doi: 10.1128/mcb.1.12.1061-1068.1981. Mol Cell Biol. 1981. PMID: 6287216 Free PMC article. - Isolation and characterization of human DNA fragments with nucleotide sequence homologies with the simian virus 40 regulatory region.
Conrad SE, Botchan MR. Conrad SE, et al. Mol Cell Biol. 1982 Aug;2(8):949-65. doi: 10.1128/mcb.2.8.949-965.1982. Mol Cell Biol. 1982. PMID: 6290874 Free PMC article. - A model for initiation at origins of DNA replication.
Bramhill D, Kornberg A. Bramhill D, et al. Cell. 1988 Sep 23;54(7):915-8. doi: 10.1016/0092-8674(88)90102-x. Cell. 1988. PMID: 2843291 Review. - SV40 virus expression vectors.
Naim HY, Roth MG. Naim HY, et al. Methods Cell Biol. 1994;43 Pt A:113-36. doi: 10.1016/s0091-679x(08)60601-9. Methods Cell Biol. 1994. PMID: 7823859 Review.
Cited by
- An amplified chromosomal sequence that includes the gene for dihydrofolate reductase initiates replication within specific restriction fragments.
Heintz NH, Hamlin JL. Heintz NH, et al. Proc Natl Acad Sci U S A. 1982 Jul;79(13):4083-7. doi: 10.1073/pnas.79.13.4083. Proc Natl Acad Sci U S A. 1982. PMID: 6955792 Free PMC article. - Unusual class of Alu sequences containing a potential Z-DNA segment.
Saffer JD, Lerman MI. Saffer JD, et al. Mol Cell Biol. 1983 May;3(5):960-4. doi: 10.1128/mcb.3.5.960-964.1983. Mol Cell Biol. 1983. PMID: 6865948 Free PMC article. - Transcription from SV 40-like monkey DNA sequences.
Saffer JD, Singer MF. Saffer JD, et al. Nucleic Acids Res. 1984 Jun 11;12(11):4769-88. doi: 10.1093/nar/12.11.4769. Nucleic Acids Res. 1984. PMID: 6330683 Free PMC article. - A cytomegalovirus DNA sequence containing tracts of tandemly repeated CA dinucleotides hybridizes to highly repetitive dispersed elements in mammalian cell genomes.
Jeang KT, Hayward GS. Jeang KT, et al. Mol Cell Biol. 1983 Aug;3(8):1389-402. doi: 10.1128/mcb.3.8.1389-1402.1983. Mol Cell Biol. 1983. PMID: 6312291 Free PMC article. - Repeat array in Epstein-Barr virus DNA is related to cell DNA sequences interspersed on human chromosomes.
Heller M, Henderson A, Kieff E. Heller M, et al. Proc Natl Acad Sci U S A. 1982 Oct;79(19):5916-20. doi: 10.1073/pnas.79.19.5916. Proc Natl Acad Sci U S A. 1982. PMID: 6310555 Free PMC article.
References
- Cell. 1978 Oct;15(2):687-701 - PubMed
- Science. 1978 May 5;200(4341):494-502 - PubMed
- J Biol Chem. 1979 Jun 25;254(12):5506-14 - PubMed
- Cell. 1979 Feb;16(2):453-66 - PubMed
- Cell. 1979 Jul;17(3):705-13 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources