The sequence of the nucleoprotein gene of human influenza A virus, strain A/NT/60/68 - PubMed (original) (raw)
Comparative Study
The sequence of the nucleoprotein gene of human influenza A virus, strain A/NT/60/68
J A Huddleston et al. Nucleic Acids Res. 1982.
Free PMC article
Abstract
The nucleotide sequence of the nucleoprotein gene of influenza A/NT/60/68 was established after using improved cloning methods to obtain full length cDNA clones in pBr322. The gene is 1565 residues long and codes for a basic protein of 498 amino acids. There are only 30 amino acid differences between it and the homologous sequence in A/PR/8/35, all occurring as point mutations. Assuming a common lineage, the evolutionary rate of divergence of the two strains is 0.18% amino acid per year. This confirms there is a slow but significant rate of evolution.
Similar articles
- Complete nucleotide sequence of the nucleoprotein gene from the human influenza strain A/PR/8/34 (HON1).
Van Rompuy L, Min Jou W, Huylebroeck D, Devos R, Fiers W. Van Rompuy L, et al. Eur J Biochem. 1981 May 15;116(2):347-53. doi: 10.1111/j.1432-1033.1981.tb05341.x. Eur J Biochem. 1981. PMID: 6166474 - Complete nucleotide sequence of the nucleoprotein gene of influenza B virus.
Londo DR, Davis AR, Nayak DP. Londo DR, et al. J Virol. 1983 Sep;47(3):642-8. doi: 10.1128/JVI.47.3.642-648.1983. J Virol. 1983. PMID: 6688639 Free PMC article. - Influenza virus RNA.
Ghendon YZ. Ghendon YZ. Acta Virol. 1982 Jul;26(4):295-300. Acta Virol. 1982. PMID: 6182780 Review. No abstract available. - [Molecular evolution of influenza A virus].
Nakajima K, Nobusawa E, Nakajima S. Nakajima K, et al. Uirusu. 1986 Dec;36(2):253-62. doi: 10.2222/jsv.36.253. Uirusu. 1986. PMID: 3551324 Review. Japanese. No abstract available.
Cited by
- Genetic Characterization of Influenza A Viruses in Japanese Swine in 2015 to 2019.
Mine J, Uchida Y, Takemae N, Saito T. Mine J, et al. J Virol. 2020 Jul 1;94(14):e02169-19. doi: 10.1128/JVI.02169-19. Print 2020 Jul 1. J Virol. 2020. PMID: 32350072 Free PMC article. - Surveillance of equine respiratory viruses in Ontario.
Diaz-Mendez A, Viel L, Hewson J, Doig P, Carman S, Chambers T, Tiwari A, Dewey C. Diaz-Mendez A, et al. Can J Vet Res. 2010 Oct;74(4):271-8. Can J Vet Res. 2010. PMID: 21197227 Free PMC article. - Comparing the ability of a series of viral protein-expressing plasmid DNAs to protect against H5N1 influenza virus.
Chen Q, Kuang H, Wang H, Fang F, Yang Z, Zhang Z, Zhang X, Chen Z. Chen Q, et al. Virus Genes. 2009 Feb;38(1):30-8. doi: 10.1007/s11262-008-0305-2. Epub 2008 Dec 10. Virus Genes. 2009. PMID: 19067149 - Caspase-dependent N-terminal cleavage of influenza virus nucleocapsid protein in infected cells.
Zhirnov OP, Konakova TE, Garten W, Klenk H. Zhirnov OP, et al. J Virol. 1999 Dec;73(12):10158-63. doi: 10.1128/JVI.73.12.10158-10163.1999. J Virol. 1999. PMID: 10559331 Free PMC article. - Generation of influenza A viruses entirely from cloned cDNAs.
Neumann G, Watanabe T, Ito H, Watanabe S, Goto H, Gao P, Hughes M, Perez DR, Donis R, Hoffmann E, Hobom G, Kawaoka Y. Neumann G, et al. Proc Natl Acad Sci U S A. 1999 Aug 3;96(16):9345-50. doi: 10.1073/pnas.96.16.9345. Proc Natl Acad Sci U S A. 1999. PMID: 10430945 Free PMC article.
References
- Proc Natl Acad Sci U S A. 1975 Oct;72(10):3961-5 - PubMed
- J Virol. 1977 Oct;24(1):401-5 - PubMed
- Nucleic Acids Res. 1978 Apr;5(4):1207-19 - PubMed
- Curr Top Microbiol Immunol. 1978;80:139-69 - PubMed
- Br Med Bull. 1979 Jan;35(1):39-46 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Research Materials