Chromosomal mapping of the simian sarcoma virus onc gene analogue in human cells - PubMed (original) (raw)

Chromosomal mapping of the simian sarcoma virus onc gene analogue in human cells

D C Swan et al. Proc Natl Acad Sci U S A. 1982 Aug.

Abstract

The primate cell-derived transforming gene (v-sis) of simian sarcoma virus (SSV) is represented as a single copy marker within cellular DNAs of mammalian species including human. The human analogue of v-sis can be distinguished from its rodent counterparts by Southern blotting analysis of EcoRI-restricted DNAs. By testing for the presence of the human v-sis-related fragment, c-sis (human), in somatic cell hybrids possessing varying numbers of human chromosome, as well as in segregants of such hybrids, it was possible to assign c-sis to human chromosome 22.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Proc Natl Acad Sci U S A. 1967 Sep;58(3):1104-11 - PubMed
    1. Proc Natl Acad Sci U S A. 1968 Apr;59(4):1132-5 - PubMed
    1. J Natl Cancer Inst. 1971 Oct;47(4):881-9 - PubMed
    1. Lancet. 1971 Oct 30;2(7731):971-2 - PubMed
    1. J Histochem Cytochem. 1973 Dec;21(12):1066-81 - PubMed

MeSH terms

LinkOut - more resources