Myelination in rabbit optic nerves is accelerated by artificial eye opening - PubMed (original) (raw)

Myelination in rabbit optic nerves is accelerated by artificial eye opening

H Tauber et al. Neurosci Lett. 1980 Mar.

Abstract

Artificial opening of the eyes of young rabbits on the 5th postnatal day led to accelerated myelination: the myelin-specific basic and proteolipid proteins nearly doubled between the 7th and the 10th postnatal days when compared to controls; 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNP) activity also increased by about 60%. Conversely, lowered AChE activities presumably reflected elevated myelin/axolemma ratios. Myelination in treated animals normalized during later ontogenetic stages (greater than 20th postnatal day).

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