Genetic mapping of the mouse proto-oncogene c-sis to chromosome 15 - PubMed (original) (raw)

Genetic mapping of the mouse proto-oncogene c-sis to chromosome 15

C A Kozak et al. Science. 1983.

Abstract

The mouse homolog (c-sis) of the transforming gene of the simian sarcoma virus was mapped to chromosome 15 by the Southern blot analysis of DNA's from hamster-mouse somatic cell hybrids. Alterations in c-sis expression may thus play a role in the various murine neoplastic diseases characterized by rearrangements or duplications of chromosome 15.

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