Renal mesangial cell cultures as a model for study of erythropoietin production - PubMed (original) (raw)
Renal mesangial cell cultures as a model for study of erythropoietin production
A Kurtz et al. Proc Natl Acad Sci U S A. 1983 Jul.
Abstract
Mesangial cells derived from isolated glomeruli of rat kidney were grown as homogeneous cell lines in culture. They released, into the culture medium, erythropoietin that had free terminal galactosyl residues and was therefore not active in vivo. The production of erythropoietin by these cells was significantly enhanced by either lowering the PO2 in the incubation atmosphere or by adding cobalt chloride to the culture medium. Therefore, mesangial cells in culture may be considered as an in vitro system in which the regulation of erythropoietin production can be studied under well-defined conditions.
Similar articles
- The functional characteristics of cultured rat mesangial cell.
Tanaka T, Fujiwara Y, Orita Y, Sasaki E, Kitamura H, Abe H. Tanaka T, et al. Jpn Circ J. 1984 Sep;48(9):1017-29. doi: 10.1253/jcj.48.1017. Jpn Circ J. 1984. PMID: 6541259 - Erythropoietin production in cultures of goat renal glomeruli.
Burlington H, Cronkite EP, Reincke U, Zanjani ED. Burlington H, et al. Proc Natl Acad Sci U S A. 1972 Dec;69(12):3547-50. doi: 10.1073/pnas.69.12.3547. Proc Natl Acad Sci U S A. 1972. PMID: 4509312 Free PMC article. - Erythropoietin production in cultures of rat renal mesangial cells.
Kurtz A, Jelkmann W, Pfeilschifter J, Bauer C. Kurtz A, et al. Contrib Nephrol. 1986;50:175-87. doi: 10.1159/000412998. Contrib Nephrol. 1986. PMID: 3026727 No abstract available. - Mesangial cells derived from rat glomeruli produce an erythropoiesis stimulating factor in cell culture.
Kurtz A, Jelkmann W, Bauer C. Kurtz A, et al. FEBS Lett. 1982 Jan 11;137(1):129-32. doi: 10.1016/0014-5793(82)80330-x. FEBS Lett. 1982. PMID: 7067818 No abstract available. - Pharmacologic modulation of erythropoietin production.
Fisher JW. Fisher JW. Annu Rev Pharmacol Toxicol. 1988;28:101-22. doi: 10.1146/annurev.pa.28.040188.000533. Annu Rev Pharmacol Toxicol. 1988. PMID: 3289482 Review.
Cited by
- Serum erythropoietin concentration and its correlation with stage of diabetic retinopathy.
Davidović S, Babić N, Jovanović S, Barišić S, Grković D, Miljković A. Davidović S, et al. BMC Ophthalmol. 2019 Nov 14;19(1):227. doi: 10.1186/s12886-019-1240-9. BMC Ophthalmol. 2019. PMID: 31727007 Free PMC article. - Critical role of the cAMP-PKA pathway in hyperglycemia-induced epigenetic activation of fibrogenic program in the kidney.
Deb DK, Bao R, Li YC. Deb DK, et al. FASEB J. 2017 May;31(5):2065-2075. doi: 10.1096/fj.201601116R. Epub 2017 Feb 1. FASEB J. 2017. PMID: 28148567 Free PMC article. - Oxygen-dependent expression of the erythropoietin gene in rat hepatocytes in vitro.
Eckardt KU, Pugh CW, Ratcliffe PJ, Kurtz A. Eckardt KU, et al. Pflugers Arch. 1993 Jun;423(5-6):356-64. doi: 10.1007/BF00374928. Pflugers Arch. 1993. PMID: 8351193 - Production of platelet-derived growth factorlike protein by rat mesangial cells in culture.
Abboud HE, Poptic E, DiCorleto P. Abboud HE, et al. J Clin Invest. 1987 Sep;80(3):675-83. doi: 10.1172/JCI113121. J Clin Invest. 1987. PMID: 3624483 Free PMC article. - Physiologic and molecular biology of erythropoietin.
Erslev AJ, Caro J. Erslev AJ, et al. Med Oncol Tumor Pharmacother. 1986;3(3-4):159-64. doi: 10.1007/BF02934992. Med Oncol Tumor Pharmacother. 1986. PMID: 3543529 Review.
References
- Virchows Arch A Pathol Anat Histol. 1982;394(3):207-20 - PubMed
- Am J Physiol. 1979 Nov;237(5):F333-43 - PubMed
- Proc Soc Exp Biol Med. 1979 Oct;162(1):65-70 - PubMed
- J Lab Clin Med. 1982 Dec;100(6):829-43 - PubMed
- Proc Natl Acad Sci U S A. 1972 Dec;69(12):3547-50 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources