The molecular biology of immunoglobulin D - PubMed (original) (raw)
. 1984 Feb;307(5950):417-22.
doi: 10.1038/307417a0.
- PMID: 6420708
- DOI: 10.1038/307417a0
The molecular biology of immunoglobulin D
F R Blattner et al. Nature. 1984 Feb.
Abstract
Immunoglobulin D (IgD) is co-expressed with immunoglobulin M (IgM) on the membranes of most B cells, yet its biological function has remained a mystery. Recent detailed information on the structure and transcription of the unusual IgD heavy chain (delta) gene in mouse suggests a complex genetic control. A model is presented for the developmental regulation of IgM and IgD and roles suggested for the membrane and secreted forms of IgD in the immune network.
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