Killing capacity of human polymorphonuclear leukocytes in aerobic and anaerobic conditions - PubMed (original) (raw)
Comparative Study
Killing capacity of human polymorphonuclear leukocytes in aerobic and anaerobic conditions
W A Vel et al. J Med Microbiol. 1984 Oct.
Abstract
The killing by human polymorphonuclear leukocytes of several species of bacteria, some of which were catalase positive, was examined in vitro in aerobic and anaerobic conditions. When all conditions other than the oxygen tension were identical, killing after 30 min was slightly greater in aerobic than in anaerobic conditions. However, after 60 and 120 min the difference between aerobic and anaerobic killing was smaller, and killing was nearly complete for all strains tested. These results conflict with the common opinion that oxygen is essential for efficient killing. Minor differences in experimental conditions can greatly influence results, and may be responsible for the discrepancy between this study and some previous studies on this subject.
Similar articles
- Phagocytosis and killing of bacteria in aerobic and anaerobic conditions.
Ingham HR, Sisson PR, Middleton RL, Narang HK, Codd AA, Selkon JB. Ingham HR, et al. J Med Microbiol. 1981 Nov;14(4):391-9. doi: 10.1099/00222615-14-4-391. J Med Microbiol. 1981. PMID: 6796693 - Bactericidal activity of aerobic and anaerobic polymorphonuclear neutrophils.
Mandell GL. Mandell GL. Infect Immun. 1974 Feb;9(2):337-41. doi: 10.1128/iai.9.2.337-341.1974. Infect Immun. 1974. PMID: 4361295 Free PMC article. - Effect of anaerobic bacteria on killing of Proteus mirabilis by human polymorphonuclear leukocytes.
Namavar F, Verweij AM, Bal M, van Steenbergen TJ, de Graaff J, MacLaren DM. Namavar F, et al. Infect Immun. 1983 Jun;40(3):930-5. doi: 10.1128/iai.40.3.930-935.1983. Infect Immun. 1983. PMID: 6133837 Free PMC article. - Interactions of polymorphonuclear leukocytes with anaerobic bacteria.
Klempner MS. Klempner MS. Rev Infect Dis. 1984 Mar-Apr;6 Suppl 1:S40-4. doi: 10.1093/clinids/6.supplement_1.s40. Rev Infect Dis. 1984. PMID: 6372036 Review. - [Endogenous aerobic and anaerobic flora of the skin in healthy people and its role in the development of suppurative processes].
Ivashkevich GA, Zvezdenkin OA. Ivashkevich GA, et al. Vestn Khir Im I I Grek. 1990 Jan;144(1):142-5. Vestn Khir Im I I Grek. 1990. PMID: 2165301 Review. Russian. No abstract available.
Cited by
- Dynamic interactions of neutrophils and biofilms.
Hirschfeld J. Hirschfeld J. J Oral Microbiol. 2014 Dec 17;6:26102. doi: 10.3402/jom.v6.26102. eCollection 2014. J Oral Microbiol. 2014. PMID: 25523872 Free PMC article. - What really happens in the neutrophil phagosome?
Hurst JK. Hurst JK. Free Radic Biol Med. 2012 Aug 1;53(3):508-20. doi: 10.1016/j.freeradbiomed.2012.05.008. Epub 2012 May 15. Free Radic Biol Med. 2012. PMID: 22609248 Free PMC article. Review. - Purification, primary structure, and antimicrobial activities of a guinea pig neutrophil defensin.
Selsted ME, Harwig SS. Selsted ME, et al. Infect Immun. 1987 Sep;55(9):2281-6. doi: 10.1128/iai.55.9.2281-2286.1987. Infect Immun. 1987. PMID: 3623703 Free PMC article. - Influence of rosmarinic acid on opsonization and intracellular killing of Escherichia coli and Staphylococcus aureus by porcine and human polymorphonuclear leucocytes.
Verweij-van Vught AM, Appelmelk BJ, Groeneveld AB, Sparrius M, Thijs LG, MacLaren DM. Verweij-van Vught AM, et al. Agents Actions. 1987 Dec;22(3-4):288-94. doi: 10.1007/BF02009058. Agents Actions. 1987. PMID: 3328496 - Assessment of neutrophil function--II. Laboratory tests of neutrophil function.
Wardle EN. Wardle EN. Postgrad Med J. 1986 Dec;62(734):1089-92. doi: 10.1136/pgmj.62.734.1089. Postgrad Med J. 1986. PMID: 3309911 Free PMC article. Review. No abstract available.