Chromosomal assignment of a family of human oncogenes - PubMed (original) (raw)

Chromosomal assignment of a family of human oncogenes

J Ryan et al. Proc Natl Acad Sci U S A. 1983 Jul.

Abstract

A family of human transforming genes, previously shown to share homology with the ras family of viral oncogenes, maps to three different human chromosomes. A well-characterized mouse-human hybrid cell panel, combined with Southern blotting, was used in this study. The transforming gene of the T24 bladder carcinoma cell line maps to human chromosome 11. An oncogene isolated from the lung carcinoma cell line SK-Calu-1 maps to human chromosome 12. The third ras-related gene, cloned from SK-N-SH, a neuroblastoma cell line, maps to human chromosome 1.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Cytogenet Cell Genet. 1975;14(3-6):279-81 - PubMed
    1. J Mol Biol. 1975 Nov 5;98(3):503-17 - PubMed
    1. Nature. 1976 Mar 11;260(5547):170-3 - PubMed
    1. Science. 1977 Apr 22;196(4288):390-405 - PubMed
    1. Cancer Res. 1977 May;37(5):1364-71 - PubMed

Publication types

MeSH terms

LinkOut - more resources