Lateral transmission of tension in frog myofibers: a myofibrillar network and transverse cytoskeletal connections are possible transmitters - PubMed (original) (raw)
Lateral transmission of tension in frog myofibers: a myofibrillar network and transverse cytoskeletal connections are possible transmitters
S F Street. J Cell Physiol. 1983 Mar.
Abstract
The extensibility of the sarcolemma of single myofibers can be reduced locally by leaving a segment covered by a sleeve of surrounding tissue composed of cut myofibers, blood vessels, and connective tissue, hereafter referred to as "the splint." Splinted fibers from frog semitendinosus muscle were used to study mechanical connections (transverse coupling) between myofibrillar components and sarcolemma. The transverse coupling is strong enough to insure a tight correlation between myofibril length and overlying sarcolemma length in both resting and activated fibers and to transmit nearly maximum isometric tension to the splint. Lateral transmission of active tension was demonstrated with a preparation which had the distal two-thirds of an intact fiber covered by a splint and the proximal third dissected clean. When the outer end of the splint was pinned down and only the distal tendon was held, tension generated in the splinted fiber was transmitted to, and recorded from, the splint. Parameters of isometric tension transmitted laterally were not significantly different from those of tension transmitted longitudinally. Myofibrils branch profusely and form a network that may act as a unitary force generator and transmitter. In splinted fibers its output is possibly picked up circumferentially and transmitted across the sarcolemma by a microfilament network. A cap of relatively inextensible sarcolemma "splints" myofiber ends. Resting tension is transmitted to and from the myofibrils by transverse coupling beyond the cap and the region of short sarcomere spacing it covers. Transverse cytoskeletal connections at Z and M regions are described. Immobilization of the sarcolemma allows study of myofibril-sarcolemma linkage in intact fibers. Both active and resting tension were transmitted laterally.
Similar articles
- Visualization of the transverse cytoskeletal network in insect-flight muscle by scanning-electron microscopy.
Trombitás K, Pollack GH. Trombitás K, et al. Cell Motil Cytoskeleton. 1995;32(3):226-32. doi: 10.1002/cm.970320306. Cell Motil Cytoskeleton. 1995. PMID: 8581977 - Lattice shrinkage with increasing resting tension in stretched, single skinned fibers of frog muscle.
Higuchi H, Umazume Y. Higuchi H, et al. Biophys J. 1986 Sep;50(3):385-9. doi: 10.1016/S0006-3495(86)83474-9. Biophys J. 1986. PMID: 3489489 Free PMC article. - Examination of intrafascicular muscle fiber terminations: implications for tension delivery in series-fibered muscles.
Young M, Paul A, Rodda J, Duxson M, Sheard P. Young M, et al. J Morphol. 2000 Aug;245(2):130-45. doi: 10.1002/1097-4687(200008)245:2<130::AID-JMOR4>3.0.CO;2-R. J Morphol. 2000. PMID: 10906747 - The cytoskeleton of skeletal muscle: is it affected by exercise? A brief review.
Waterman-Storer CM. Waterman-Storer CM. Med Sci Sports Exerc. 1991 Nov;23(11):1240-9. Med Sci Sports Exerc. 1991. PMID: 1766338 Review. - [Lateral mechanics of muscle fibres and its role in signaling].
Ogneva IV, Lebedev DV, Shenkman BS. Ogneva IV, et al. Biofizika. 2009 May-Jun;54(3):522-8. Biofizika. 2009. PMID: 19569516 Review. Russian.
Cited by
- Effects of Aging on Collagen in the Skeletal Muscle of Mice.
Kanazawa Y, Miyachi R, Higuchi T, Sato H. Kanazawa Y, et al. Int J Mol Sci. 2023 Aug 23;24(17):13121. doi: 10.3390/ijms241713121. Int J Mol Sci. 2023. PMID: 37685934 Free PMC article. - Transcriptome Profiling Reveals Enhanced Mitochondrial Activity as a Cold Adaptive Strategy to Hypothermia in Zebrafish Muscle.
Cahill T, Chan S, Overton IM, Hardiman G. Cahill T, et al. Cells. 2023 May 11;12(10):1366. doi: 10.3390/cells12101366. Cells. 2023. PMID: 37408201 Free PMC article. - Exercise metabolism and adaptation in skeletal muscle.
Smith JAB, Murach KA, Dyar KA, Zierath JR. Smith JAB, et al. Nat Rev Mol Cell Biol. 2023 Sep;24(9):607-632. doi: 10.1038/s41580-023-00606-x. Epub 2023 May 24. Nat Rev Mol Cell Biol. 2023. PMID: 37225892 Free PMC article. Review. - Structure-Function relationships in the skeletal muscle extracellular matrix.
Lieber RL, Meyer G. Lieber RL, et al. J Biomech. 2023 May;152:111593. doi: 10.1016/j.jbiomech.2023.111593. Epub 2023 Apr 17. J Biomech. 2023. PMID: 37099932 Free PMC article. Review. - Morphology of proximal and distal human semitendinosus compartments and the effects of distal tendon harvesting for anterior cruciate ligament reconstruction.
Kositsky A, Maas H, Barrett RS, Kennedy B, Stenroth L, Korhonen RK, Vertullo CJ, Diamond LE, Saxby DJ. Kositsky A, et al. J Anat. 2023 Aug;243(2):297-310. doi: 10.1111/joa.13869. Epub 2023 Apr 13. J Anat. 2023. PMID: 37057314 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous