Effect of vitamin C supplements on cell-mediated immunity in old people - PubMed (original) (raw)
Clinical Trial
Effect of vitamin C supplements on cell-mediated immunity in old people
B Kennes et al. Gerontology. 1983.
Abstract
Both ageing and vitamin C (VC) deficiency result in immune defect. Since low serum and tissue levels of VC are found in the elderly, we have in a placebo-controlled study, tested the effect of VC supplements (500 mg/day i.m. for 1 month) on various immune parameters. Indeed, VC enhances the proliferative response of T lymphocytes in vitro, and the tuberculin skin hypersensitivity in vivo. Neither the serum concentrations of IgA, IgG and IgM, nor the proportion of E-rosette-forming cells were modified. No significant change was observed in the placebo-treated group.
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