Complete nucleotide sequence of the nucleoprotein gene of influenza B virus - PubMed (original) (raw)
Comparative Study
Complete nucleotide sequence of the nucleoprotein gene of influenza B virus
D R Londo et al. J Virol. 1983 Sep.
Abstract
A DNA copy of influenza B/Singapore/222/79 viral RNA segment 5, containing the gene coding for the nucleoprotein (NP), has been cloned in Escherichia coli plasmid pBR322, and its nucleotide sequence has been determined. The influenza B NP gene contains 1,839 nucleotides and codes for a protein of 560 amino acids with a molecular weight of 61,593. Comparison of the influenza B NP amino acid sequence with that of influenza A NP (A/PR/8/34) reveals 37% direct homology in the aligned regions, indicating a common ancestor. However, influenza B NP has an additional 50 amino acids at its N-terminal end. As is the case with influenza A NP, influenza B NP is a basic protein, with its charged residues relatively evenly distributed rather than clustered. The structural homology suggests functional similarity between the NP of influenza A and B viruses.
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References
- J Virol. 1972 Oct;10(4):689-97 - PubMed
- J Virol. 1975 Oct;16(4):790-6 - PubMed
- Virology. 1976 Sep;73(2):327-38 - PubMed
- Proc Natl Acad Sci U S A. 1977 Feb;74(2):560-4 - PubMed
- J Virol. 1978 Feb;25(2):685-6 - PubMed
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