Orientation of nucleosomes and linker DNA in calf thymus chromatin determined by photochemical dichroism - PubMed (original) (raw)

. 1984 Mar;308(5956):247-50.

doi: 10.1038/308247a0.

• PMID: 6700728
• DOI: 10.1038/308247a0

Orientation of nucleosomes and linker DNA in calf thymus chromatin determined by photochemical dichroism

S Mitra et al. Nature. 1984 Mar.

Abstract

The dichroism for photochemical attachment of a psoralen derivative to Mg2+-stabilized chromatin fibres is used to deduce the orientation of nucleosomal disks and linker DNA in the 30-nm fibre. The new technique of photochemical electric dichroism should have general applicability to problems of nucleic acid organization in cellular subunits and viruses.

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