Recombination and chromosome segregation during the single division meiosis in SPO12-1 and SPO13-1 diploids - PubMed (original) (raw)

Recombination and chromosome segregation during the single division meiosis in SPO12-1 and SPO13-1 diploids

S Klapholz et al. Genetics. 1980 Nov.

Abstract

This paper reports a study of chromosome segregation and recombination during sporulation of spo12-1 and spo13-1 diploid strains of S. cerevisiae. These strains undergo a single division to form asci containing two diploid or near-diploid spores. The segregation of centromere-linked markers in the two-spored (dyad) products indicates that the division is generally equational. However, in a small percentage of the spo12-1 and spo13-1 cells, it appears that a meiosis I-like division occurs. Aberrant segregation of the MAT locus on chromosome III, yielding a monosomic and a trisomic spores pair, occurs in 12% of all dyads. The segregation patterns of markers at various distances from their centromeres and several pairs of markers on the same chromosome indicate that recombination takes place in both strains at nearly standard meiotic levels.

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References

1. 1. Genetics. 1978 Apr;88(4 Pt 1):651-71 - PubMed
2. 1. J Cell Sci. 1974 Dec;16(3):519-27 - PubMed
3. 1. Genetics. 1955 Jul;40(4):546-61 - PubMed
4. 1. Genetics. 1966 Jan;53(1):165-73 - PubMed
5. 1. Genetics. 1971 Apr;67(4):483-95 - PubMed

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