A large particle associated with the perimeter of the nuclear pore complex - PubMed (original) (raw)
A large particle associated with the perimeter of the nuclear pore complex
P N Unwin et al. J Cell Biol. 1982 Apr.
Abstract
The three-dimensional structure of the nuclear pore complex has been determined to a resolution of approximately 90 A by electron microscopy using nuclear envelopes from Xenopus oocytes. It is shown to be an assembly of several discrete constituents arranged with octagonal symmetry about a central axis. There are apparent twofold axes perpendicular to the octad axis which suggest that the framework of the pore complex is constructed from two equal but oppositely facing halves. The half facing the cytoplasm is in some instances decorated by large particles, similar in appearance and size to ribosomes.
Similar articles
- Correlation between structure and mass distribution of the nuclear pore complex and of distinct pore complex components.
Reichelt R, Holzenburg A, Buhle EL Jr, Jarnik M, Engel A, Aebi U. Reichelt R, et al. J Cell Biol. 1990 Apr;110(4):883-94. doi: 10.1083/jcb.110.4.883. J Cell Biol. 1990. PMID: 2324201 Free PMC article. - Movement of a karyophilic protein through the nuclear pores of oocytes.
Feldherr CM, Kallenbach E, Schultz N. Feldherr CM, et al. J Cell Biol. 1984 Dec;99(6):2216-22. doi: 10.1083/jcb.99.6.2216. J Cell Biol. 1984. PMID: 6501421 Free PMC article. - Structural and functional organization of the nuclear envelope.
Goldberg MW, Allen TD. Goldberg MW, et al. Curr Opin Cell Biol. 1995 Jun;7(3):301-9. doi: 10.1016/0955-0674(95)80083-2. Curr Opin Cell Biol. 1995. PMID: 7662358 Review. - Nuclear envelopes from amphibian oocytes--from morphology to protein inventory.
Scheer U, Dabauvalle MC, Krohne G, Peiman Zahedi R, Sickmann A. Scheer U, et al. Eur J Cell Biol. 2005 Mar;84(2-3):151-62. doi: 10.1016/j.ejcb.2004.12.001. Eur J Cell Biol. 2005. PMID: 15819397 Review. No abstract available.
Cited by
- Integral membrane proteins specific to the inner nuclear membrane and associated with the nuclear lamina.
Senior A, Gerace L. Senior A, et al. J Cell Biol. 1988 Dec;107(6 Pt 1):2029-36. doi: 10.1083/jcb.107.6.2029. J Cell Biol. 1988. PMID: 3058715 Free PMC article. - Ion channels in murine nuclei during early development and in fully differentiated adult cells.
Mazzanti M, DeFelice LJ, Smith EF. Mazzanti M, et al. J Membr Biol. 1991 Apr;121(2):189-98. doi: 10.1007/BF01870532. J Membr Biol. 1991. PMID: 1715405 - Implications of a multiscale structure of the yeast nuclear pore complex.
Akey CW, Echeverria I, Ouch C, Nudelman I, Shi Y, Wang J, Chait BT, Sali A, Fernandez-Martinez J, Rout MP. Akey CW, et al. Mol Cell. 2023 Sep 21;83(18):3283-3302.e5. doi: 10.1016/j.molcel.2023.08.025. Mol Cell. 2023. PMID: 37738963 Free PMC article. - Functionalization of a nanopore: the nuclear pore complex paradigm.
Peters R. Peters R. Biochim Biophys Acta. 2009 Oct;1793(10):1533-9. doi: 10.1016/j.bbamcr.2009.06.003. Epub 2009 Jul 9. Biochim Biophys Acta. 2009. PMID: 19596381 Free PMC article. Review. - nup1 mutants exhibit pleiotropic defects in nuclear pore complex function.
Bogerd AM, Hoffman JA, Amberg DC, Fink GR, Davis LI. Bogerd AM, et al. J Cell Biol. 1994 Oct;127(2):319-32. doi: 10.1083/jcb.127.2.319. J Cell Biol. 1994. PMID: 7929578 Free PMC article.
References
- J Biophys Biochem Cytol. 1959 Oct;6:147-56 - PubMed
- J Cell Biol. 1967 Feb;32(2):391-9 - PubMed
- J Mol Biol. 1965 Aug;13(1):1-12 - PubMed
- J Mol Biol. 1966 Aug;19(2):503-24 - PubMed
- J Sci Instrum. 1969 May;2(5):385-7 - PubMed