"Pink" diarrhoea: osmotic diarrhoea from a sorbitol-containing vitamin C supplement - PubMed (original) (raw)
Case Reports
"Pink" diarrhoea: osmotic diarrhoea from a sorbitol-containing vitamin C supplement
R E Hill et al. Med J Aust. 1982.
Abstract
Sorbitol was the sole cause of protracted diarrhoea in seven children seen in two paediatric-gastroenterology outpatient departments. The sorbitol had been administered in the form of a vitamin C supplement in all seven children. Pink staining of napkins was a prominent feature in five of these seven patients, and was attributed to the cochineal dye contained in the vitamin C supplement. In children with chronic or intermittent watery diarrhoea, a careful dietary history should be obtained. If sorbitol ingestion is documented, a trial of sorbitol exclusion is recommended before embarking on extensive investigations.
Similar articles
- 'Halloween diarrhea'. An unexpected trick of sorbitol-containing candy.
Breitenbach RA. Breitenbach RA. Postgrad Med. 1992 Oct;92(5):63-6. doi: 10.1080/00325481.1992.11701482. Postgrad Med. 1992. PMID: 1409181 - Sorbitol: Often forgotten cause of osmotic diarrhea.
Liauw S, Saibil F. Liauw S, et al. Can Fam Physician. 2019 Aug;65(8):557-558. Can Fam Physician. 2019. PMID: 31413027 Free PMC article. No abstract available. - Rice gruel and rice starch reduce sorbitol-induced diarrhoea in cecectomized rats.
Islam MS, Nishiyama A, Sakaguchi E. Islam MS, et al. Digestion. 2005;72(1):13-21. doi: 10.1159/000087398. Epub 2005 Aug 10. Digestion. 2005. PMID: 16103671 - [Sugar substitutes in the diabetic diet].
Mehnert H. Mehnert H. Int Z Vitam Ernahrungsforsch Beih. 1976;15:295-324. Int Z Vitam Ernahrungsforsch Beih. 1976. PMID: 783058 Review. German. - Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection.
Humphreys EH, Smith NA, Azman H, McLeod D, Rutherford GW. Humphreys EH, et al. Cochrane Database Syst Rev. 2010 Jun 16;(6):CD008563. doi: 10.1002/14651858.CD008563. Cochrane Database Syst Rev. 2010. PMID: 20556793 Review.
Cited by
- A modern view of excipient effects on bioequivalence: case study of sorbitol.
Chen ML, Straughn AB, Sadrieh N, Meyer M, Faustino PJ, Ciavarella AB, Meibohm B, Yates CR, Hussain AS. Chen ML, et al. Pharm Res. 2007 Jan;24(1):73-80. doi: 10.1007/s11095-006-9120-4. Epub 2006 Oct 18. Pharm Res. 2007. PMID: 17048115 Clinical Trial. - Hypernatremia associated with cathartics in overdose management.
Caldwell JW, Nava AJ, de Haas DD. Caldwell JW, et al. West J Med. 1987 Nov;147(5):593-6. West J Med. 1987. PMID: 3424825 Free PMC article. No abstract available.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical