Myoglobinuria, rhabdomyolysis and marathon running - PubMed (original) (raw)
. 1978 Oct;47(188):463-72.
- PMID: 751088
Myoglobinuria, rhabdomyolysis and marathon running
H B Schiff et al. Q J Med. 1978 Oct.
Abstract
Rhabdomyolysis, secondary to exertion is known to result in myoglobinuria and is occasionally associated with acute renal failure. In this study myoglobinaemia occurred in 25 of 44 runners completing a 99 km marathon. A marked rise in the values of myoglobin, lactate and the enzymes creatine kinase (CPK), aspartate transaminase (AST) and lactic dehydrogenase (LDH) was noted. A linear correlation was demonstrated between the level of serum myoglobin and the serum concentrations of urate, CPK, AST and LDH. Both the myoglobin itself and the increased concentration of urate may contribute to the acute renal failure. The pathophysiology of rhabdomyolysis during exertion is discussed in the context of other causes of myoglobinuria. A classification of rhabdomyolysis and myoglobinuria is suggested.
Similar articles
- Rhabdomyolysis and acute renal failure in a marathon runner in Israel.
Bar-Sela S, Tur-Kaspa R, Eliakim M. Bar-Sela S, et al. Isr J Med Sci. 1979 May;15(5):464-6. Isr J Med Sci. 1979. PMID: 447519 No abstract available. - Exercise myoglobinemia and acute exertional rhabdomyolysis.
Demos MA, Gitin EL, Kagen LJ. Demos MA, et al. Arch Intern Med. 1974 Oct;134(4):669-73. Arch Intern Med. 1974. PMID: 4472107 No abstract available. - Acute renal failure in severe exertional rhabdomyolysis.
Uberoi HS, Dugal JS, Kasthuri AS, Kolhe VS, Kumar AK, Cruz SA. Uberoi HS, et al. J Assoc Physicians India. 1991 Sep;39(9):677-9. J Assoc Physicians India. 1991. PMID: 1814900 - [Myoglobinuria. Clinical aspects].
Pokrzywnicki W, Strojek K, Grzeszczak W. Pokrzywnicki W, et al. Wiad Lek. 1994 May;47(9-10):364-7. Wiad Lek. 1994. PMID: 7817595 Review. Polish. - [Rhabdomyolysis in a medical student induced by body-building exercise (rhabdomyolysis following acute muscular exertion)].
Arányi J, Radó J. Arányi J, et al. Orv Hetil. 1992 Aug 2;133(31):1965-7. Orv Hetil. 1992. PMID: 1495807 Review. Hungarian.
Cited by
- Perspectives on Exertional Rhabdomyolysis.
Rawson ES, Clarkson PM, Tarnopolsky MA. Rawson ES, et al. Sports Med. 2017 Mar;47(Suppl 1):33-49. doi: 10.1007/s40279-017-0689-z. Sports Med. 2017. PMID: 28332112 Free PMC article. Review. - Vascular and myofibrillar lesions in acute myoglobinuria associated with carnitine-palmityl-transferase deficiency.
Mantz J, Hindelang C, Mantz JM, Stoeckel ME. Mantz J, et al. Virchows Arch A Pathol Anat Histopathol. 1992;421(1):57-64. doi: 10.1007/BF01607140. Virchows Arch A Pathol Anat Histopathol. 1992. PMID: 1636250 - Pacing During and Physiological Response After a 12-Hour Ultra-Marathon in a 95-Year-Old Male Runner.
Knechtle B, Jastrzebski Z, Rosemann T, Nikolaidis PT. Knechtle B, et al. Front Physiol. 2019 Jan 4;9:1875. doi: 10.3389/fphys.2018.01875. eCollection 2018. Front Physiol. 2019. PMID: 30687109 Free PMC article. - Do some marathon runners bleed into the gut?
Porter AM. Porter AM. Br Med J (Clin Res Ed). 1983 Nov 12;287(6403):1427. doi: 10.1136/bmj.287.6403.1427. Br Med J (Clin Res Ed). 1983. PMID: 6416441 Free PMC article. No abstract available. - Exertional rhabdomyolysis in a collegiate american football player after preventive cold-water immersion: a case report.
Kahanov L, Eberman LE, Wasik M, Alvey T. Kahanov L, et al. J Athl Train. 2012 Mar-Apr;47(2):228-32. doi: 10.4085/1062-6050-47.2.228. J Athl Train. 2012. PMID: 22488291 Free PMC article.