Growth-phase regulation of plasmid virulence genes in Salmonella - PubMed (original) (raw)
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Growth-phase regulation of plasmid virulence genes in Salmonella
D G Guiney et al. Trends Microbiol. 1995 Jul.
Abstract
Virulence genes in the genus Salmonella are regulated by growth phase and by environmental signals, which allows a sequential program of expression during infection. Conditions that promote the expression of loci required in systemic infection, including the plasmid-encoded spv genes, are the opposite of the factors that induce genes involved in the invasion of epithelial cells in the gastrointestinal tract.