The matrix protein gene determines amantadine-sensitivity of influenza viruses - PubMed (original) (raw)
The matrix protein gene determines amantadine-sensitivity of influenza viruses
A J Hay et al. J Gen Virol. 1979 Jan.
Abstract
The genetic composition of several recombinant strains, produced by mixed infection with an amantadine-sensitive and an amantadine-resistant influenza virus, have been compared with their response to amantadine. It is concluded that transfer of resistance or sensitivity to amantadine is determined by a single gene, that coding for the matrix protein.
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