Effects of cocaine on cortisol secretion in humans - PubMed (original) (raw)

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Effects of cocaine on cortisol secretion in humans

C M Heesch et al. Am J Med Sci. 1995 Aug.

Abstract

The effects of acute cocaine administration on the pituitary adrenal axis in humans without a history of drug abuse are unknown. The authors studied 12 male volunteers twice in a double-blinded, placebo-controlled, randomized fashion. After intranasal administration of 2 mg/kg cocaine, cortisol levels were significantly higher than after placebo administration. The authors concluded that acute administration of cocaine to humans increases cortisol secretion.

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